{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:34:21Z","timestamp":1786649661620,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"\n Background:<\/jats:title>\n Varicocele is a reversible cause of male infertility. However, there are conflicting data available concerning the benefit of varicocele repair for patients with nonobstructive azoospermia (NOA) and severe oligoasthenoteratozoospermia (OAT).<\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n To address the benefit of varicocelectomy in patients with severe OAT and NOA with regard to their semen parameters and surgical sperm retrieval rate in those who underwent testicular sperm extraction (TESE) or testicular sperm aspiration (TESA).<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n This retrospective cohort study was conducted on a sample of 13 patients diagnosed with NOA and severe OAT who underwent varicocelectomy for infertility treatment with no prespecified exclusion criteria.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Thirteen patients were enrolled. Five patients were diagnosed with NOA; eight were diagnosed with severe OAT. For improvements in the semen parameters postoperatively, the semen concentration of all patients was significantly increased compared to the preoperative concentration (3.59 \u00b1 10.0.8 vs. 0.25 \u00b1 0.31,\n P<\/jats:italic>\n = 0.02) and the remaining parameters were unchanged. Regarding sperm retrieval, three patients underwent TESE and two patients underwent TESA, in which all had positive results.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Varicocele repair was found to improve the semen parameters in patients with NOA and severe OAT and produced a successful surgical sperm retrieval rate in all patients who underwent TESA or TESE.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ua.ua_24_23","type":"journal-article","created":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T01:00:08Z","timestamp":1700096408000},"page":"60-63","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Varicocelectomy outcomes among patients with azoospermia and severe oligasthenoteratozoospermia"],"prefix":"10.4103","volume":"16","author":[{"given":"Abdullah","family":"Alkhayal","sequence":"first","affiliation":[{"name":"Division of Urology, Department of Surgery, Ministry of the National Guard \u2013 Health Affairs, King Abdulaziz Medical City, Riyadh, Saudi Arabia"},{"name":"King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar","family":"Aljumaiah","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery, Ministry of the National Guard \u2013 Health Affairs, King Abdulaziz Medical City, Riyadh, Saudi Arabia"},{"name":"King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Alyami","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery, Ministry of the National Guard \u2013 Health Affairs, King Abdulaziz Medical City, Riyadh, Saudi Arabia"},{"name":"King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad","family":"Abumelha","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery, Ministry of the National Guard \u2013 Health Affairs, King Abdulaziz Medical City, Riyadh, Saudi Arabia"},{"name":"King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid","family":"Alrabeeah","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery, Ministry of the National Guard \u2013 Health Affairs, King Abdulaziz Medical City, Riyadh, Saudi Arabia"},{"name":"King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,11,15]]},"reference":[{"key":"R2-20260428","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1016\/j.juro.2010.02.012","article-title":"Varicocele repair in patients with nonobstructive azoospermia: A meta-analysis","volume":"183","author":"Weedin","year":"2010","journal-title":"J Urol"},{"issue":"Suppl 1","key":"R3-20260428","doi-asserted-by":"crossref","first-page":"89","DOI":"10.6061\/clinics\/2013(Sup01)10","article-title":"The role of varicocele treatment in the management of non-obstructive azoospermia","volume":"68","author":"Inci","year":"2013","journal-title":"Clinics (Sao Paulo)"},{"key":"R4-20260428","doi-asserted-by":"crossref","first-page":"459.","DOI":"10.4103\/1008-682X.148719","article-title":"Clinical management of infertile men with non-obstructive azoospermia","volume":"17","author":"Esteves","year":"2015","journal-title":"Asian J Androl"},{"key":"R5-20260428","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.eururo.2010.12.008","article-title":"Does varicocele repair improve male infertility? An evidence-based perspective from a randomized, controlled trial","volume":"59","author":"Abdel-Meguid","year":"2011","journal-title":"Eur Urol"},{"key":"R6-20260428","doi-asserted-by":"crossref","first-page":"182","DOI":"10.4111\/icu.2018.59.3.182","article-title":"Microscopic varicocelectomy as a treatment option for patients with severe oligospermia","volume":"59","author":"Gupta","year":"2018","journal-title":"Investig Clin Urol"},{"key":"R7-20260428","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.urology.2017.10.010","article-title":"Men with severe oligospermia appear to benefit from varicocele repair: A cost-effectiveness analysis of assisted reproductive technology","volume":"111","author":"Dubin","year":"2018","journal-title":"Urology"},{"key":"R8-20260428","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1016\/j.fertnstert.2003.10.036","article-title":"Role of varicocelectomy in men with nonobstructive azoospermia","volume":"81","author":"Schlegel","year":"2004","journal-title":"Fertil Steril"},{"key":"R9-20260428","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0015-0282(98)00108-3","article-title":"Induction of spermatogenesis and achievement of pregnancy after microsurgical varicocelectomy in men with azoospermia and severe oligoasthenospermia","volume":"70","author":"Matthews","year":"1998","journal-title":"Fertil Steril"}],"container-title":["Urology Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ua.ua_24_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:56:38Z","timestamp":1786647398000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ua.ua_24_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,15]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ua.ua_24_23","relation":{},"ISSN":["0974-7796","0974-7834"],"issn-type":[{"value":"0974-7796","type":"print"},{"value":"0974-7834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,15]]},"assertion":[{"value":"2023-02-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}