{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:27:10Z","timestamp":1790702830224,"version":"4.1.0"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Because the reports in the literature of radiologic investigations for upper tract urothelial cancer (UTUC) are limited by the number of patients, and included patients with different pathologies, we aimed to study the overall accuracy of computed tomography (CT) in the diagnosis of UTUC and their accuracy on predicting tumor location.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A retrospective review from 1990 to 2017 included patients who were treated for UTUC. Unenhanced CT scan was obtained first using Multi-Detector Computed Tomography (MDCT, Philips Medical Systems), then nonionic contrast medium, containing 350 mg iodine\/ml was injected at 4 mL\/s. Analysis was performed using SPSS\n                      <jats:sup>\u00ae<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of 275 patients, complete data on CT was available on 270 (98%) patients. CT reported only two false positive and six false negative results and the overall accuracy was 96-97%. In comparison to the final pathological reports, CT\/CTU detected 85% of the tumor location of in the renal pelvic and 50% of the calyceal tumors. In ureteric tumors, they detected distal (66\/71= 93%) more than proximal ureteric tumors (60%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In our cohort, CT\/ CTU has a high overall accuracy (97%) in diagnosing UTUC, capability to well visualize tumors of distal ureter and renal pelvis, but could miss calyceal tumors. The matter to rely only on CT without ureteroscopic biopsy in the diagnosis of UTUC especially if radical surgery is planned needs further prospective studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ua.ua_32_20","type":"journal-article","created":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T10:42:09Z","timestamp":1630579329000},"page":"356-361","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["The accuracy of computed tomography in the diagnosis of upper urinary tract urothelial carcinoma in correlation with the final histopathology"],"prefix":"10.4103","volume":"13","author":[{"given":"Rasha T.","family":"Abouelkheir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Mohamed","family":"Elawdy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diaa Eldin","family":"Taha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Abd","family":"El-Hamid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasser","family":"Osman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarek","family":"El-Diasty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20240828","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.juro.2006.09.065","article-title":"The role of computerized tomographic urography in the initial evaluation of hematuria","volume":"177","author":"Albani","year":"2007","journal-title":"J Urol"},{"key":"R2-6-20240828","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1148\/radiol.2472070798","article-title":"Small (<2-cm) upper-tract urothelial carcinoma: Evaluation with gadolinium-enhanced three-dimensional spoiled gradient-recalled echo MR urography","volume":"247","author":"Takahashi","year":"2008","journal-title":"Radiology"},{"key":"R3-6-20240828","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1016\/S0022-5347(05)64167-5","article-title":"Prospective comparison of computerized tomography and excretory urography in the initial evaluation of asymptomatic microhematuria","volume":"168","author":"Gray Sears","year":"2002","journal-title":"J Urol"},{"key":"R4-6-20240828","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1016\/j.juro.2010.02.028","article-title":"Tumor characteristics of urothelial carcinoma on multidetector computerized tomography urography","volume":"183","author":"Wang","year":"2010","journal-title":"J Urol"},{"key":"R5-6-20240828","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.crad.2009.11.003","article-title":"MR urography versus retrograde pyelography\/ureteroscopy for the exclusion of upper urinary tract malignancy","volume":"65","author":"Lee","year":"2010","journal-title":"Clin Radiol"},{"key":"R6-6-20240828","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.2214\/AJR.10.5249","article-title":"Comparison of CT urography and excretory urography in the detection and localization of urothelial carcinoma of the upper urinary tract","volume":"196","author":"Jinzaki","year":"2011","journal-title":"AJR Am J Roentgenol"},{"key":"R7-6-20240828","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1097\/00000478-199812000-00001","article-title":"The World Health Organization\/International Society of Urological Pathology consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder. 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