{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:43:33Z","timestamp":1786725813400,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Social determinants of health (SDOH) impact whether a patient will report lower urinary tract symptoms (LUTS). Since management of benign prostatic hyperplasia is guided by symptoms, it is important to understand the drivers of symptom severity. This study investigated the relationship between neighborhood-level SDOH and the severity of LUTS in men.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Men who completed the International Prostate Symptom Score (IPSS) at a single institution from October 25, 2018, to July 31, 2024, were retrospectively analyzed. High social vulnerability index (SVI) neighborhoods were defined as those in the 75\n                      <jats:sup>th<\/jats:sup>\n                      percentile or above. IPSS scores were compared between high and low SVI groups. Results were stratified into storage, voiding, or quality of life (QOL) domains. Adjustment for confounding was achieved with linear regression models adjusting for age, race, ethnicity, and number of medical comorbidities.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study included 20,795 patients, with 1351 (6.5%) from high SVI communities. The high SVI group reported worse overall (10.5 vs. 9.6;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), storage (5.4 vs. 5.0;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), voiding (5.1 vs. 4.6;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), and QOL (2.8 vs. 2.5;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) scores. Age and number of comorbidities were independently associated with worse AUA-SI scores, while nonwhite race and Latinx ethnicity showed no association on multivariable analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>High SVI patients report more severe LUTS at initial urologic referral. Delayed access to primary and urologic care in high SVI patients may lead to worse symptoms. Our findings highlight the importance of lowering barriers to urologic care for underserved groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ua.ua_81_25","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T16:00:22Z","timestamp":1768924822000},"page":"37-40","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Neighborhood-level socioeconomic status impacts the severity of lower urinary tract symptoms in men"],"prefix":"10.4103","volume":"18","author":[{"given":"Carl A.","family":"Ceraolo","sequence":"first","affiliation":[{"name":"Department of Urology, University of Rochester Medical Center, Rochester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle C.","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Y.","family":"Song","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumya","family":"Konar","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Rochester Medical Center, Rochester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajat K.","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Rochester Medical Center, Rochester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott O.","family":"Quarrier","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Rochester Medical Center, Rochester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"R1-20260417","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1016\/S0140-6736(12)61729-2","article-title":"Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"Vos","year":"2012","journal-title":"Lancet"},{"key":"R2-20260417","doi-asserted-by":"crossref","first-page":"170","DOI":"10.4103\/0970-1591.126900","article-title":"Epidemiology and etiology of benign prostatic hyperplasia and bladder outlet obstruction","volume":"30","author":"Patel","year":"2014","journal-title":"Indian J Urol"},{"key":"R3-20260417","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1016\/j.juro.2008.07.059","article-title":"Race and socioeconomic status are independently associated with benign prostatic hyperplasia","volume":"180","author":"Fowke","year":"2008","journal-title":"J Urol"},{"key":"R4-20260417","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s11606-011-1776-8","article-title":"Association between socioeconomic status (SES) and lower urinary tract symptom (LUTS) severity among black and white men","volume":"26","author":"Fowke","year":"2011","journal-title":"J Gen Intern Med"},{"key":"R5-20260417","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1016\/S0140-6736(08)61690-6","article-title":"Closing the gap in a generation: Health equity through action on the social determinants of health","volume":"372","author":"Marmot","year":"2008","journal-title":"Lancet"},{"key":"R6-20260417","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1111\/j.1742-1241.2012.02988.x","article-title":"Sociodemographic and lifestyle factors affecting the self-perception period of lower urinary tract symptoms of international prostate symptom score items","volume":"66","author":"Kim","year":"2012","journal-title":"Int J Clin Pract"},{"key":"R7-20260417","doi-asserted-by":"crossref","first-page":"e13125","DOI":"10.1111\/and.13125","article-title":"Association between the symptoms of benign prostatic hyperplasia and social disparities: Does social capital promote prostate health?","volume":"50","author":"Park","year":"2018","journal-title":"Andrologia"},{"key":"R8-20260417","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/JU.0000000000003698","article-title":"Management of lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH): AUA guideline amendment 2023","volume":"211","author":"Sandhu","year":"2024","journal-title":"J Urol"},{"key":"R9-20260417","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/luts.12415","article-title":"How international is the international prostate symptom score? A literature review of validated translations of the IPSS, the most widely used self-administered patient questionnaire for male lower urinary tract symptoms","volume":"14","author":"Yao","year":"2022","journal-title":"Low Urin Tract Symptoms"},{"key":"R10-20260417","first-page":"1","article-title":"A Social Vulnerability Index for Disaster Management","volume":"8","author":"Flanagan","year":"2011","journal-title":"J Homel Secur Emerg"},{"key":"R11-20260417","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1097\/BRS.0000000000004977","article-title":"Disparities in patient-reported outcome measure completion rates and baseline function in newly presenting spine patients","volume":"49","author":"Johnson","year":"2024","journal-title":"Spine (Phila Pa 1976)"},{"key":"R12-20260417","doi-asserted-by":"crossref","first-page":"e30091","DOI":"10.1097\/MD.0000000000030091","article-title":"Factors associated with quality of life in patients with benign prostatic hyperplasia, 2009\u20132016","volume":"101","author":"Park","year":"2022","journal-title":"Medicine (Baltimore)"}],"container-title":["Urology Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ua.ua_81_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:26:04Z","timestamp":1786724764000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ua.ua_81_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ua.ua_81_25","relation":{},"ISSN":["0974-7796","0974-7834"],"issn-type":[{"value":"0974-7796","type":"print"},{"value":"0974-7834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-06-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}