{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:34:02Z","timestamp":1786649642340,"version":"build-2736575974"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"\n Background:<\/jats:title>\n Catheter-associated urinary tract infections (CAUTI) are among the most common healthcare-associated infections, particularly in hospitalised patients requiring prolonged catheterisation. Despite standard protocols, preventable lapses in catheter care and clinical practices contribute to the incidence of these infections.<\/jats:p>\n <\/jats:sec>\n \n Aims and Objectives:<\/jats:title>\n This study aimed to identify significant risk factors and develop a point-based CAUTI Risk Scoring System for early prediction and intervention.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n A prospective observational study was conducted over six months at a tertiary care hospital, including 100 catheterized adult inpatients. Demographic data, Clinical variables, and catheter practices were documented. CAUTI was confirmed by urine culture. A risk stratification model was developed by assigning weighted scores to statistically significant variables, categorising patients into low, moderate, and high CAUTI risk groups. A domain-wise heatmap visually represented the novelty and interdisciplinary relevance of the study\u2019s contributions across ten clinical research domains.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Among the 26% of study participants who had CAUTI overall, the important procedural predictors were open-type drainage systems (p < 0.00001), kinking of catheter tubing (p < 0.00001), and raised urobag placement (p < 0.00001). Clinical risk variables included diabetes mellitus (p = 0.00001), catheter duration greater than 7 days (p = 0.0043), female sex (p = 0.0023), and immobility (p = 0.0014). Strong early signals included turbid urine (p = 0.00004) and unexplained fever (p = 0.00001). A cumulative risk rating system placed patients into low (0\u20133), moderate (4\u20136), and high-risk (\u22657) categories.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n This study presents the first validated CAUTI Risk Scoring System, including clinical, procedural, and early bedside indicators. The scoring tool enables proactive intervention and serves as a necessary adjunct to infection prevention plans in hospital environments.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ua.ua_86_25","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T14:00:33Z","timestamp":1775829633000},"page":"127-140","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Closing the loop on catheter-associated urinary tract infections: A prospective risk assessment and scoring system for the early prediction and prevention of catheter-associated urinary tract infection"],"prefix":"10.4103","volume":"18","author":[{"given":"Rajan","family":"Ravichandran","sequence":"first","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshan Yedulla","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Velmurugan","family":"Palaniyandi","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hariharasudhan","family":"Sekar","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sriram","family":"Krishnamoorthy","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"key":"R1-20260415","doi-asserted-by":"crossref","first-page":"342","DOI":"10.3201\/eid0702.010240","article-title":"Engineering out the risk for infection with urinary catheters","volume":"7","author":"Maki","year":"2001","journal-title":"Emerg Infect Dis"},{"issue":"Suppl 1","key":"R2-20260415","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1016\/j.ijantimicag.2006.05.011","article-title":"Incidence of nosocomial urinary tract infections on a surgical intensive care unit and implications for management","volume":"28","author":"Wagenlehner","year":"2006","journal-title":"Int J Antimicrob Agents"},{"key":"R3-20260415","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.jhin.2005.07.013","article-title":"High prevalence of nosocomial infections in rehabilitation units accounted for by urinary tract infections in patients with spinal cord injury","volume":"62","author":"Girard","year":"2006","journal-title":"J Hosp Infect"},{"key":"R4-20260415","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1086\/503339","article-title":"Device-associated infection rates for non-intensive care unit patients","volume":"27","author":"Vonberg","year":"2006","journal-title":"Infect Control Hosp Epidemiol"},{"key":"R5-20260415","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1086\/518518","article-title":"Underresourced hospital infection control and prevention programs: Penny wise, pound foolish?","volume":"28","author":"Anderson","year":"2007","journal-title":"Infect Control Hosp Epidemiol"},{"key":"R6-20260415","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1001\/archinte.159.8.800","article-title":"Preventing catheter-related bacteriuria: Should we? 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