{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:47:48Z","timestamp":1777682868150,"version":"3.51.4"},"reference-count":62,"publisher":"XMLink","issue":"2","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2023-NR076997"],"award-info":[{"award-number":["RS-2023-NR076997"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["immunenetwork.org"],"crossmark-restriction":false},"short-container-title":["Immune Netw"],"DOI":"10.4110\/in.2026.26.e17","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:19:35Z","timestamp":1777450775000},"update-policy":"https:\/\/doi.org\/10.4110\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cigarette Smoke Induces the Pro-inflammatory Response of Lung Macrophages via Activation of the IL-33\/ST2-Dependent Pathway"],"prefix":"10.4110","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9838-5441","authenticated-orcid":false,"given":"Yujin","family":"Kim","sequence":"first","affiliation":[{"name":"Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 03080, Korea."},{"name":"Department of Translational Medicine, Seoul National University College of Medicine, Seoul 03080, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0095-4464","authenticated-orcid":false,"given":"Yosep","family":"Mo","sequence":"additional","affiliation":[{"name":"Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 03080, Korea."},{"name":"Department of Translational Medicine, Seoul National University College of Medicine, Seoul 03080, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6859-4595","authenticated-orcid":false,"given":"Ji-Young","family":"Bang","sequence":"additional","affiliation":[{"name":"Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 03080, Korea."},{"name":"Department of Translational Medicine, Seoul National University College of Medicine, Seoul 03080, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1222-0345","authenticated-orcid":false,"given":"Jihyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 03080, Korea."},{"name":"Department of Biomedical Science, Seoul National University College of Medicine, Seoul 03080, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6157-5631","authenticated-orcid":false,"given":"In-Gu","family":"Lee","sequence":"additional","affiliation":[{"name":"Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 03080, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5978-512X","authenticated-orcid":false,"given":"Hye Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 03080, Korea."},{"name":"Department of Biomedical Science, Seoul National University College of Medicine, Seoul 03080, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2317-4201","authenticated-orcid":false,"given":"Hye-Ryun","family":"Kang","sequence":"additional","affiliation":[{"name":"Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 03080, Korea."},{"name":"Department of Translational Medicine, Seoul National University College of Medicine, Seoul 03080, Korea."},{"name":"Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","published-online":{"date-parts":[[2026]]},"reference":[{"key":"10.4110\/in.2026.26.e17_ref1","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1136\/thoraxjnl-2017-210722","volume":"73","author":"Bhatt","year":"2018","journal-title":"Thorax"},{"key":"10.4110\/in.2026.26.e17_ref2","doi-asserted-by":"crossref","first-page":"808260","DOI":"10.1155\/2012\/808260","volume":"2012","author":"Oh","year":"2012","journal-title":"Pulm Med"},{"key":"10.4110\/in.2026.26.e17_ref3","doi-asserted-by":"crossref","first-page":"4111","DOI":"10.3390\/ijerph7124111","volume":"7","author":"Mazzone","year":"2010","journal-title":"Int J Environ Res Public Health"},{"key":"10.4110\/in.2026.26.e17_ref4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.resp.2013.01.013","volume":"187","author":"Rom","year":"2013","journal-title":"Respir Physiol Neurobiol"},{"key":"10.4110\/in.2026.26.e17_ref5","doi-asserted-by":"crossref","first-page":"e0248535","DOI":"10.1371\/journal.pone.0248535","volume":"16","author":"Chang","year":"2021","journal-title":"PLoS One"},{"key":"10.4110\/in.2026.26.e17_ref6","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1136\/thx.2010.143800","volume":"66","author":"Hedman","year":"2011","journal-title":"Thorax"},{"key":"10.4110\/in.2026.26.e17_ref7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/SHK.0000000000001601","volume":"55","author":"Mu","year":"2021","journal-title":"Shock"},{"key":"10.4110\/in.2026.26.e17_ref8","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1136\/thoraxjnl-2020-216296","volume":"77","author":"Lugg","year":"2022","journal-title":"Thorax"},{"key":"10.4110\/in.2026.26.e17_ref9","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1080\/15412555.2021.1978419","volume":"18","author":"Tajbakhsh","year":"2021","journal-title":"COPD"},{"key":"10.4110\/in.2026.26.e17_ref10","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.biopha.2016.09.093","volume":"84","author":"Xu","year":"2016","journal-title":"Biomed Pharmacother"},{"key":"10.4110\/in.2026.26.e17_ref11","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.4049\/jimmunol.180.2.1169","volume":"180","author":"Doz","year":"2008","journal-title":"J Immunol"},{"key":"10.4110\/in.2026.26.e17_ref12","doi-asserted-by":"crossref","first-page":"L46","DOI":"10.1152\/ajplung.00241.2005","volume":"291","author":"Yang","year":"2006","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.4110\/in.2026.26.e17_ref13","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1165\/rcmb.2018-0294OC","volume":"62","author":"Suzuki","year":"2020","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.4110\/in.2026.26.e17_ref14","doi-asserted-by":"crossref","first-page":"4232","DOI":"10.1128\/IAI.00305-09","volume":"77","author":"Mart\u00ed-Lliteras","year":"2009","journal-title":"Infect Immun"},{"key":"10.4110\/in.2026.26.e17_ref15","doi-asserted-by":"crossref","first-page":"1602434","DOI":"10.1183\/13993003.02434-2016","volume":"50","author":"Le Rouzic","year":"2017","journal-title":"Eur Respir J"},{"key":"10.4110\/in.2026.26.e17_ref16","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.intimp.2012.09.011","volume":"14","author":"Wang","year":"2012","journal-title":"Int Immunopharmacol"},{"key":"10.4110\/in.2026.26.e17_ref17","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.toxlet.2022.02.004","volume":"360","author":"Russell","year":"2022","journal-title":"Toxicol Lett"},{"key":"10.4110\/in.2026.26.e17_ref18","doi-asserted-by":"crossref","first-page":"959","DOI":"10.2147\/COPD.S155754","volume":"13","author":"Liang","year":"2018","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"10.4110\/in.2026.26.e17_ref19","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/j.jaci.2021.09.031","volume":"149","author":"Shin","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.4110\/in.2026.26.e17_ref20","first-page":"350727","volume":"2013","author":"Duan","year":"2013","journal-title":"Clin Dev Immunol"},{"key":"10.4110\/in.2026.26.e17_ref21","doi-asserted-by":"crossref","first-page":"571","DOI":"10.3389\/fimmu.2015.00571","volume":"6","author":"Roberts","year":"2015","journal-title":"Front Immunol"},{"key":"10.4110\/in.2026.26.e17_ref22","first-page":"385352","volume":"2014","author":"Zheng","year":"2014","journal-title":"J Immunol Res"},{"key":"10.4110\/in.2026.26.e17_ref23","doi-asserted-by":"crossref","first-page":"4432","DOI":"10.4049\/jimmunol.0900576","volume":"183","author":"Bradshaw","year":"2009","journal-title":"J Immunol"},{"key":"10.4110\/in.2026.26.e17_ref24","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s12931-023-02357-x","volume":"24","author":"Choi","year":"2023","journal-title":"Respir Res"},{"key":"10.4110\/in.2026.26.e17_ref25","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1183\/09031936.04.00032904","volume":"25","author":"Lind\u00e9n","year":"2005","journal-title":"Eur Respir J"},{"key":"10.4110\/in.2026.26.e17_ref26","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nri3600","volume":"14","author":"Hussell","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"10.4110\/in.2026.26.e17_ref27","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0147-9571(94)90009-4","volume":"17","author":"Ortega","year":"1994","journal-title":"Comp Immunol Microbiol Infect Dis"},{"key":"10.4110\/in.2026.26.e17_ref28","doi-asserted-by":"crossref","first-page":"13392","DOI":"10.1038\/s41598-017-13888-x","volume":"7","author":"Eapen","year":"2017","journal-title":"Sci Rep"},{"key":"10.4110\/in.2026.26.e17_ref29","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.3390\/ijms18091940","volume":"18","author":"Oliveira da Silva","year":"2017","journal-title":"Int J Mol Sci"},{"key":"10.4110\/in.2026.26.e17_ref30","doi-asserted-by":"crossref","first-page":"1325090","DOI":"10.3389\/fimmu.2024.1325090","volume":"15","author":"Wohnhaas","year":"2024","journal-title":"Front Immunol"},{"key":"10.4110\/in.2026.26.e17_ref31","doi-asserted-by":"crossref","first-page":"e40","DOI":"10.4110\/in.2022.22.e40","volume":"22","author":"Mo","year":"2022","journal-title":"Immune Netw"},{"key":"10.4110\/in.2026.26.e17_ref32","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.3389\/fphar.2019.01387","volume":"10","author":"Marone","year":"2019","journal-title":"Front Pharmacol"},{"key":"10.4110\/in.2026.26.e17_ref33","doi-asserted-by":"crossref","first-page":"928134","DOI":"10.3389\/fimmu.2022.928134","volume":"13","author":"Liu","year":"2022","journal-title":"Front Immunol"},{"key":"10.4110\/in.2026.26.e17_ref34","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.it.2004.09.015","volume":"25","author":"Mantovani","year":"2004","journal-title":"Trends Immunol"},{"key":"10.4110\/in.2026.26.e17_ref35","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1038\/ni1488","volume":"8","author":"Zhou","year":"2007","journal-title":"Nat Immunol"},{"key":"10.4110\/in.2026.26.e17_ref36","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1038\/ni1496","volume":"8","author":"Acosta-Rodriguez","year":"2007","journal-title":"Nat Immunol"},{"key":"10.4110\/in.2026.26.e17_ref37","doi-asserted-by":"crossref","first-page":"105151","DOI":"10.1016\/j.isci.2022.105151","volume":"25","author":"Zeng","year":"2022","journal-title":"iScience"},{"key":"10.4110\/in.2026.26.e17_ref38","doi-asserted-by":"crossref","first-page":"949","DOI":"10.3389\/fimmu.2017.00949","volume":"8","author":"Trist\u00e3o","year":"2017","journal-title":"Front Immunol"},{"key":"10.4110\/in.2026.26.e17_ref39","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.bbrc.2014.05.073","volume":"450","author":"Wu","year":"2014","journal-title":"Biochem Biophys Res Commun"},{"key":"10.4110\/in.2026.26.e17_ref40","doi-asserted-by":"crossref","first-page":"L1192","DOI":"10.1152\/ajplung.00099.2012","volume":"302","author":"Robinson","year":"2012","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.4110\/in.2026.26.e17_ref41","doi-asserted-by":"crossref","first-page":"8765","DOI":"10.1073\/pnas.1601914113","volume":"113","author":"Gordon","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.4110\/in.2026.26.e17_ref42","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/intimm\/dxr006","volume":"23","author":"Louten","year":"2011","journal-title":"Int Immunol"},{"key":"10.4110\/in.2026.26.e17_ref43","doi-asserted-by":"crossref","first-page":"6469","DOI":"10.4049\/jimmunol.0901575","volume":"183","author":"Kurowska-Stolarska","year":"2009","journal-title":"J Immunol"},{"key":"10.4110\/in.2026.26.e17_ref44","doi-asserted-by":"crossref","first-page":"739489","DOI":"10.3389\/fmed.2021.739489","volume":"8","author":"Dong","year":"2021","journal-title":"Front Med (Lausanne)"},{"key":"10.4110\/in.2026.26.e17_ref45","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.cyto.2017.07.022","volume":"99","author":"Park","year":"2017","journal-title":"Cytokine"},{"key":"10.4110\/in.2026.26.e17_ref46","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.imlet.2019.12.003","volume":"218","author":"Park","year":"2020","journal-title":"Immunol Lett"},{"key":"10.4110\/in.2026.26.e17_ref47","first-page":"9543083","volume":"2022","author":"Cheng","year":"2022","journal-title":"J Immunol Res"},{"key":"10.4110\/in.2026.26.e17_ref48","doi-asserted-by":"crossref","first-page":"L429","DOI":"10.1152\/ajplung.00252.2011","volume":"302","author":"Cho","year":"2012","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.4110\/in.2026.26.e17_ref49","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1097\/ACI.0000000000000133","volume":"15","author":"Divekar","year":"2015","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.4110\/in.2026.26.e17_ref50","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.3390\/ijerph15051033","volume":"15","author":"Strzelak","year":"2018","journal-title":"Int J Environ Res Public Health"},{"key":"10.4110\/in.2026.26.e17_ref51","doi-asserted-by":"crossref","first-page":"e711","DOI":"10.1002\/iid3.711","volume":"10","author":"Lin","year":"2022","journal-title":"Immun Inflamm Dis"},{"key":"10.4110\/in.2026.26.e17_ref52","doi-asserted-by":"crossref","first-page":"e24097","DOI":"10.1371\/journal.pone.0024097","volume":"6","author":"Eltom","year":"2011","journal-title":"PLoS One"},{"key":"10.4110\/in.2026.26.e17_ref53","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1165\/rcmb.2010-0038OC","volume":"44","author":"Lucattelli","year":"2011","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.4110\/in.2026.26.e17_ref54","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1016\/j.bbadis.2014.06.009","volume":"1842","author":"Pace","year":"2014","journal-title":"Biochim Biophys Acta"},{"key":"10.4110\/in.2026.26.e17_ref55","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1136\/thoraxjnl-2020-214712","volume":"76","author":"Huang","year":"2021","journal-title":"Thorax"},{"key":"10.4110\/in.2026.26.e17_ref56","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.immuni.2015.02.011","volume":"42","author":"Kearley","year":"2015","journal-title":"Immunity"},{"key":"10.4110\/in.2026.26.e17_ref57","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.immuni.2015.02.014","volume":"42","author":"Liew","year":"2015","journal-title":"Immunity"},{"key":"10.4110\/in.2026.26.e17_ref58","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.cytogfr.2023.12.001","volume":"76","author":"He","year":"2024","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.4110\/in.2026.26.e17_ref59","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1186\/s12967-023-04782-4","volume":"21","author":"Zhou","year":"2023","journal-title":"J Transl Med"},{"key":"10.4110\/in.2026.26.e17_ref60","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.immuni.2005.09.015","volume":"23","author":"Schmitz","year":"2005","journal-title":"Immunity"},{"key":"10.4110\/in.2026.26.e17_ref61","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1139\/bcb-2014-0163","volume":"93","author":"Shang","year":"2015","journal-title":"Biochem Cell Biol"},{"key":"10.4110\/in.2026.26.e17_ref62","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.4049\/jimmunol.0803067","volume":"183","author":"Espinassous","year":"2009","journal-title":"J Immunol"}],"container-title":["Immune Network"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/immunenetwork.org\/pdf\/10.4110\/in.2026.26.e17","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/immunenetwork.org\/DOIx.php?id=10.4110\/in.2026.26.e17","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/immunenetwork.org\/DOIx.php?id=10.4110\/in.2026.26.e17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:44:21Z","timestamp":1777452261000},"score":1,"resource":{"primary":{"URL":"https:\/\/immunenetwork.org\/DOIx.php?id=10.4110\/in.2026.26.e17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":62,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4110\/in.2026.26.e17","relation":{},"ISSN":["1598-2629","2092-6685"],"issn-type":[{"value":"1598-2629","type":"print"},{"value":"2092-6685","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"2025-07-09","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-02","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-05","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-23","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2026. The Korean Association of Immunologists","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}],"article-number":"e17"}}