{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T13:59:31Z","timestamp":1781359171261,"version":"3.54.1"},"reference-count":34,"publisher":"XMLink","issue":"6","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["icurology.org"],"crossmark-restriction":false},"short-container-title":["Investig Clin Urol"],"published-print":{"date-parts":[[2025]]},"DOI":"10.4111\/icu.20250310","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T05:51:26Z","timestamp":1760075486000},"page":"559","update-policy":"https:\/\/doi.org\/10.4111\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Induction of apoptosis and growth inhibition by silodosin and abiraterone acetate in PC-3 human prostate cancer cells"],"prefix":"10.4111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1518-8010","authenticated-orcid":false,"given":"Lukman","family":"Hakim","sequence":"first","affiliation":[{"name":"Department of Urology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia."},{"name":"Department of Urology, Rumah Sakit Universitas Airlangga Teaching Hospital, Surabaya, Indonesia."},{"name":"Department of Medicine, Faculty of Medicine and Health, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2442-0996","authenticated-orcid":false,"given":"Zakaria Aulia","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia."},{"name":"Department of Urology, Rumah Sakit Universitas Airlangga Teaching Hospital, Surabaya, Indonesia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7479-2704","authenticated-orcid":false,"given":"Furqan","family":"Hidayatullah","sequence":"additional","affiliation":[{"name":"Faculty of Science, Technology, and Health Sciences, Bina Bangsa Getsempena University, Aceh, Indonesia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1723-9646","authenticated-orcid":false,"given":"Anthony Chi-Fai","family":"Ng","sequence":"additional","affiliation":[{"name":"S.H. Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Shatin, Hong Kong."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.4111\/icu.20250310_ref1","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.eururo.2024.11.013","volume":"87","author":"Schafer","year":"2025","journal-title":"Eur Urol"},{"key":"10.4111\/icu.20250310_ref2","first-page":"365","volume":"4","author":"Chandrasekar","year":"2015","journal-title":"Transl Androl Urol"},{"key":"10.4111\/icu.20250310_ref3","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1158\/1078-0432.CCR-18-1431","volume":"25","author":"Mostaghel","year":"2019","journal-title":"Clin Cancer Res"},{"key":"10.4111\/icu.20250310_ref4","doi-asserted-by":"crossref","first-page":"466","DOI":"10.4111\/icu.20230128","volume":"64","author":"Jeong","year":"2023","journal-title":"Investig Clin Urol"},{"key":"10.4111\/icu.20250310_ref5","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.eururo.2021.06.021","volume":"80","author":"Sternberg","year":"2021","journal-title":"Eur Urol"},{"key":"10.4111\/icu.20250310_ref6","doi-asserted-by":"crossref","first-page":"3608","DOI":"10.1200\/JCO.22.01726","volume":"41","author":"Gillessen","year":"2023","journal-title":"J Clin Oncol"},{"key":"10.4111\/icu.20250310_ref7","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.prnil.2023.12.002","volume":"12","author":"Fujita","year":"2024","journal-title":"Prostate Int"},{"key":"10.4111\/icu.20250310_ref8","doi-asserted-by":"crossref","first-page":"793","DOI":"10.3892\/ijo.2015.3274","volume":"48","author":"Grossebrummel","year":"2016","journal-title":"Int J Oncol"},{"key":"10.4111\/icu.20250310_ref9","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s00210-019-01622-5","volume":"392","author":"Fragni","year":"2019","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.4111\/icu.20250310_ref10","doi-asserted-by":"crossref","first-page":"e948","DOI":"10.52225\/narra.v4i3.948","volume":"4","author":"Rahman","year":"2024","journal-title":"Narra J"},{"key":"10.4111\/icu.20250310_ref11","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1016\/j.clinthera.2009.11.024","volume":"31","author":"Schilit","year":"2009","journal-title":"Clin Ther"},{"issue":"5","key":"10.4111\/icu.20250310_ref12","first-page":"38","author":"Chapple","year":"2012","journal-title":"Urologiia"},{"key":"10.4111\/icu.20250310_ref13","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1002\/pros.23164","volume":"76","author":"Kawahara","year":"2016","journal-title":"Prostate"},{"key":"10.4111\/icu.20250310_ref14","first-page":"2959","volume":"5","author":"Kawahara","year":"2015","journal-title":"Am J Cancer Res"},{"key":"10.4111\/icu.20250310_ref15","first-page":"16","volume":"17","author":"Kaighn","year":"1979","journal-title":"Invest Urol"},{"key":"10.4111\/icu.20250310_ref16","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1111\/iju.14667","volume":"28","author":"Maesaka","year":"2021","journal-title":"Int J Urol"},{"key":"10.4111\/icu.20250310_ref17","doi-asserted-by":"crossref","first-page":"e385","DOI":"10.1016\/j.ijrobp.2011.04.026","volume":"81","author":"Tsumura","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.4111\/icu.20250310_ref18","doi-asserted-by":"crossref","first-page":"e680","DOI":"10.52225\/narra.v4i1.680","volume":"4","author":"Hidayatullah","year":"2024","journal-title":"Narra J"},{"key":"10.4111\/icu.20250310_ref19","first-page":"4941","volume":"21","author":"Masciovecchio","year":"2017","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.4111\/icu.20250310_ref20","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/pros.24297","volume":"82","author":"Moll","year":"2022","journal-title":"Prostate"},{"key":"10.4111\/icu.20250310_ref21","doi-asserted-by":"crossref","first-page":"100761","DOI":"10.1016\/j.drup.2021.100761","volume":"56","author":"Buck","year":"2021","journal-title":"Drug Resist Updat"},{"key":"10.4111\/icu.20250310_ref22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpba.2016.11.013","volume":"134","author":"Vishnuvardhan","year":"2017","journal-title":"J Pharm Biomed Anal"},{"key":"10.4111\/icu.20250310_ref23","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/s41391-019-0134-5","volume":"22","author":"Nickols","year":"2019","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.4111\/icu.20250310_ref24","doi-asserted-by":"crossref","first-page":"169170","DOI":"10.1155\/2012\/169170","volume":"2012","author":"Rodriguez-Berriguete","year":"2012","journal-title":"J Signal Transduct"},{"key":"10.4111\/icu.20250310_ref25","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s12079-022-00702-1","volume":"17","author":"Hashemi","year":"2023","journal-title":"J Cell Commun Signal"},{"key":"10.4111\/icu.20250310_ref26","doi-asserted-by":"crossref","first-page":"29365","DOI":"10.1074\/jbc.M109.007971","volume":"284","author":"Xiao","year":"2009","journal-title":"J Biol Chem"},{"key":"10.4111\/icu.20250310_ref27","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/sj.bjc.6604904","volume":"100","author":"Ang","year":"2009","journal-title":"Br J Cancer"},{"key":"10.4111\/icu.20250310_ref28","doi-asserted-by":"crossref","first-page":"13","DOI":"10.2147\/DDDT.S15850","volume":"6","author":"Rehman","year":"2012","journal-title":"Drug Des Devel Ther"},{"key":"10.4111\/icu.20250310_ref29","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1016\/j.febslet.2006.03.041","volume":"580","author":"Alimirah","year":"2006","journal-title":"FEBS Lett"},{"key":"10.4111\/icu.20250310_ref30","doi-asserted-by":"crossref","first-page":"700543","DOI":"10.3389\/fonc.2021.700543","volume":"11","author":"Wright","year":"2021","journal-title":"Front Oncol"},{"key":"10.4111\/icu.20250310_ref31","first-page":"291","volume":"4","author":"Rossi","year":"2010","journal-title":"Drug Des Devel Ther"},{"key":"10.4111\/icu.20250310_ref32","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.1038\/s41467-023-39310-x","volume":"14","author":"Toyoda","year":"2023","journal-title":"Nat Commun"},{"key":"10.4111\/icu.20250310_ref33","doi-asserted-by":"crossref","first-page":"652152","DOI":"10.3389\/fcell.2021.652152","volume":"9","author":"Perez","year":"2021","journal-title":"Front Cell Dev Biol"},{"key":"10.4111\/icu.20250310_ref34","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.canlet.2019.05.025","volume":"459","author":"Cao","year":"2019","journal-title":"Cancer Lett"}],"container-title":["Investigative and Clinical Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/icurology.org\/pdf\/10.4111\/icu.20250310","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/icurology.org\/DOIx.php?id=10.4111\/icu.20250310","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/icurology.org\/DOIx.php?id=10.4111\/icu.20250310","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:25:25Z","timestamp":1761899125000},"score":1,"resource":{"primary":{"URL":"https:\/\/icurology.org\/DOIx.php?id=10.4111\/icu.20250310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4111\/icu.20250310","relation":{},"ISSN":["2466-0493","2466-054X"],"issn-type":[{"value":"2466-0493","type":"print"},{"value":"2466-054X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"2025-07-09","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-06","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-24","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 The Korean Urological Association","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}