{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:44:38Z","timestamp":1792813478948,"version":"4.5.0"},"reference-count":32,"publisher":"XMLink","issue":"6","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100021363","name":"Busan Paik Hospital, Inje University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["icurology.org"],"crossmark-restriction":false},"short-container-title":["Investig Clin Urol"],"published-print":{"date-parts":[[2025]]},"DOI":"10.4111\/icu.20250313","type":"journal-article","created":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T23:16:32Z","timestamp":1760915792000},"page":"516","update-policy":"https:\/\/doi.org\/10.4111\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Comparative effectiveness of androgen receptor pathway inhibitor treatment intensification for metastatic hormone-sensitive prostate cancer in real-world patients"],"prefix":"10.4111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7750-6806","authenticated-orcid":false,"given":"Chan Ho","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Urology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3818-5149","authenticated-orcid":false,"given":"Soodong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology, Dong-A University College of Medicine, Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3460-9386","authenticated-orcid":false,"given":"Ja Yoon","family":"Ku","sequence":"additional","affiliation":[{"name":"Department of Urology, Dongnam Institute of Radiological & Medical Sciences Korea Cancer Center Hospital, Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7162-6527","authenticated-orcid":false,"given":"Kyung Hwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4498-5895","authenticated-orcid":false,"given":"Byeong Jin","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Urology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7854-7562","authenticated-orcid":false,"given":"Hyeok Jun","family":"Goh","sequence":"additional","affiliation":[{"name":"Department of Urology, Dong-A University College of Medicine, Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3004-101X","authenticated-orcid":false,"given":"Won IK","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Urology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8240-7765","authenticated-orcid":false,"given":"Hong Koo","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Urology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea."},{"name":"Biomedical Research Institute, Pusan National University Hospital, Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.4111\/icu.20250313_ref1","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.6004\/jnccn.2023.0050","volume":"21","author":"Schaeffer","year":"2023","journal-title":"J Natl Compr Canc Netw"},{"key":"10.4111\/icu.20250313_ref2","doi-asserted-by":"crossref","first-page":"102171","DOI":"10.1016\/j.clgc.2024.102171","volume":"22","author":"Sternberg","year":"2024","journal-title":"Clin Genitourin Cancer"},{"key":"10.4111\/icu.20250313_ref3","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1056\/NEJMoa1903307","volume":"381","author":"Chi","year":"2019","journal-title":"N Engl J Med"},{"key":"10.4111\/icu.20250313_ref4","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1200\/JCO.19.00799","volume":"37","author":"Armstrong","year":"2019","journal-title":"J Clin Oncol"},{"key":"10.4111\/icu.20250313_ref5","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1056\/NEJMoa1702900","volume":"377","author":"James","year":"2017","journal-title":"N Engl J Med"},{"key":"10.4111\/icu.20250313_ref6","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1056\/NEJMoa1704174","volume":"377","author":"Fizazi","year":"2017","journal-title":"N Engl J Med"},{"key":"10.4111\/icu.20250313_ref7","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/bju.16577","volume":"135","author":"Raval","year":"2025","journal-title":"BJU Int"},{"key":"10.4111\/icu.20250313_ref8","doi-asserted-by":"crossref","first-page":"903","DOI":"10.2217\/fon-2023-0814","volume":"20","author":"Goebell","year":"2024","journal-title":"Future Oncol"},{"key":"10.4111\/icu.20250313_ref9","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.euf.2021.04.003","volume":"8","author":"Wenzel","year":"2022","journal-title":"Eur Urol Focus"},{"key":"10.4111\/icu.20250313_ref10","doi-asserted-by":"crossref","first-page":"394","DOI":"10.4103\/jcrt.JCRT_23_20","volume":"19","author":"Mutlu","year":"2023","journal-title":"J Cancer Res Ther"},{"key":"10.4111\/icu.20250313_ref11","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1056\/NEJMoa1503747","volume":"373","author":"Sweeney","year":"2015","journal-title":"N Engl J Med"},{"key":"10.4111\/icu.20250313_ref12","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.eururo.2024.04.010","volume":"86","author":"Tilki","year":"2024","journal-title":"Eur Urol"},{"key":"10.4111\/icu.20250313_ref13","doi-asserted-by":"crossref","first-page":"102140","DOI":"10.1016\/j.clgc.2024.102140","volume":"22","author":"Suzuki","year":"2024","journal-title":"Clin Genitourin Cancer"},{"key":"10.4111\/icu.20250313_ref14","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/pros.24813","volume":"85","author":"Yanagisawa","year":"2025","journal-title":"Prostate"},{"key":"10.4111\/icu.20250313_ref15","doi-asserted-by":"crossref","first-page":"252.e19","DOI":"10.1016\/j.urolonc.2023.03.013","volume":"41","author":"Lowentritt","year":"2023","journal-title":"Urol Oncol"},{"key":"10.4111\/icu.20250313_ref16","doi-asserted-by":"crossref","first-page":"253.e1","DOI":"10.1016\/j.urolonc.2023.03.003","volume":"41","author":"Lowentritt","year":"2023","journal-title":"Urol Oncol"},{"key":"10.4111\/icu.20250313_ref17","doi-asserted-by":"crossref","unstructured":"Prostate Cancer Prostatic. Dis 2024 Dec 20.  https:\/\/doi.org\/10.1038\/s41391-024-00929-6","DOI":"10.1038\/s41391-024-00929-6"},{"key":"10.4111\/icu.20250313_ref18","doi-asserted-by":"crossref","first-page":"1494073","DOI":"10.3389\/fonc.2024.1494073","volume":"14","author":"Anton","year":"2024","journal-title":"Front Oncol"},{"key":"10.4111\/icu.20250313_ref19","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1007\/s00345-022-04189-8","volume":"41","author":"Kafka","year":"2023","journal-title":"World J Urol"},{"key":"10.4111\/icu.20250313_ref20","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.prnil.2023.10.003","volume":"12","author":"L\u00f3pez-Abad","year":"2024","journal-title":"Prostate Int"},{"key":"10.4111\/icu.20250313_ref21","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.annonc.2023.02.009","volume":"34","author":"Chowdhury","year":"2023","journal-title":"Ann Oncol"},{"key":"10.4111\/icu.20250313_ref22","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.euros.2024.10.001","volume":"70","author":"Hassi Roman","year":"2024","journal-title":"Eur Urol Open Sci"},{"key":"10.4111\/icu.20250313_ref23","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/pros.24885","volume":"85","author":"Shimomura","year":"2025","journal-title":"Prostate"},{"key":"10.4111\/icu.20250313_ref24","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/pros.24847","volume":"85","author":"Suzuki","year":"2025","journal-title":"Prostate"},{"key":"10.4111\/icu.20250313_ref25","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.euf.2024.06.008","volume":"10","author":"Turco","year":"2024","journal-title":"Eur Urol Focus"},{"issue":"16 suppl","key":"10.4111\/icu.20250313_ref26","first-page":"TPS5129","volume":"43","author":"Ong","year":"2025","journal-title":"J Clin Oncol"},{"key":"10.4111\/icu.20250313_ref27","author":"Pons-Fuster","year":"2025","journal-title":"Int J Clin Pharm"},{"key":"10.4111\/icu.20250313_ref28","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1002\/pros.23967","volume":"80","author":"Shore","year":"2020","journal-title":"Prostate"},{"key":"10.4111\/icu.20250313_ref29","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.acuro.2024.03.002","volume":"48","author":"Borque-Fernando","year":"2024","journal-title":"Actas Urol Esp (Engl Ed)"},{"key":"10.4111\/icu.20250313_ref30","doi-asserted-by":"crossref","first-page":"521","DOI":"10.4111\/icu.20230103","volume":"64","author":"Neerhut","year":"2023","journal-title":"Investig Clin Urol"},{"key":"10.4111\/icu.20250313_ref31","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.prnil.2024.10.003","volume":"13","author":"Kim","year":"2025","journal-title":"Prostate Int"},{"key":"10.4111\/icu.20250313_ref32","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.prnil.2024.10.002","volume":"13","author":"Lee","year":"2025","journal-title":"Prostate Int"}],"container-title":["Investigative and Clinical Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/icurology.org\/pdf\/10.4111\/icu.20250313","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/icurology.org\/DOIx.php?id=10.4111\/icu.20250313","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/icurology.org\/DOIx.php?id=10.4111\/icu.20250313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:25:14Z","timestamp":1761899114000},"score":1,"resource":{"primary":{"URL":"https:\/\/icurology.org\/DOIx.php?id=10.4111\/icu.20250313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4111\/icu.20250313","relation":{},"ISSN":["2466-0493","2466-054X"],"issn-type":[{"value":"2466-0493","type":"print"},{"value":"2466-054X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"2025-07-08","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-23","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-13","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 The Korean Urological Association","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}