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Secondary, ABC-like changes can complicate a variety of other benign and malignant primary bone neoplasms, including giant cell tumor, fibrous dysplasia, and osteosarcoma. About two-third of primary ABCs have a rearrangement of the &lt;i&gt;USP6&lt;\/i&gt; gene, which is not present in the ABC-like changes that occur secondary to other primary bone tumors (i.e., secondary ABC). Primary ABC of bone carries a variable but generally high rate of local recurrence. This paper provides an overview of the pathophysiology, clinical presentation, radiographic and pathologic findings, treatment, and prognosis of ABC.<\/jats:p>","DOI":"10.4132\/jptm.2023.02.23","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:49:34Z","timestamp":1679273374000},"page":"81-87","update-policy":"https:\/\/doi.org\/10.4132\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Aneurysmal bone cyst: a review"],"prefix":"10.4132","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5894-5865","authenticated-orcid":true,"given":"Elham","family":"Nasri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John 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