{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T13:29:42Z","timestamp":1780752582506,"version":"3.54.1"},"reference-count":12,"publisher":"The Korean Society of Pathologists and The Korean Society for Cytopathology","issue":"2","license":[{"start":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T00:00:00Z","timestamp":1730332800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["jpatholtm.org"],"crossmark-restriction":true},"short-container-title":["J Pathol Transl Med"],"published-print":{"date-parts":[[2025,3,15]]},"abstract":"<jats:p>Hepatic Epstein-Barr virus\u2013positive inflammatory follicular dendritic cell sarcoma (EBV+ IFDCS) represents a rare form of liver malignancy. The absence of distinct clinical and radiological characteristics, compounded by its rare occurrence, contributes to a challenging diagnosis. Here, we report a case of a 54-year-old Chinese female with a background of chronic hepatitis B virus treated with entecavir and complicated by advanced fibrosis presenting with a liver mass found on her annual surveillance ultrasound. Hepatectomy was performed under clinical suspicion of hepatocellular carcinoma. Immunomorphologic characteristics of the tumor were consistent with EBV+ IFDCS with distinct non-caseating granulomatous inflammation. Our case illustrates the importance of considering EBV+ IFDCS in the differential diagnosis of hepatic inflammatory lesions. Awareness of this entity and its characteristic features is essential for accurately diagnosing and managing this rare neoplasm.<\/jats:p>","DOI":"10.4132\/jptm.2024.09.27","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T05:14:44Z","timestamp":1730265284000},"page":"133-138","update-policy":"https:\/\/doi.org\/10.4132\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Uncommon granulomatous manifestation in Epstein-Barr virus\u2013positive follicular dendritic cell sarcoma: a case report"],"prefix":"10.4132","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0145-3625","authenticated-orcid":true,"given":"Henry Goh Di","family":"Shen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8113-1185","authenticated-orcid":true,"given":"Yue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6003-9837","authenticated-orcid":true,"given":"Wei Qiang","family":"Leow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2611","reference":[{"key":"ref1","first-page":"2421","volume-title":"Clinicopathologic characteristics of inflammatory pseudotumor-like follicular dendritic cell sarcoma","author":"Ge","year":"2014"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1192998"},{"key":"ref3","first-page":"721","volume-title":"Inflammatory pseudotumorlike follicular dendritic cell tumor: a distinctive low-grade malignant intra-abdominal neoplasm with consistent Epstein-Barr virus association","author":"Cheuk","year":"2001"},{"key":"ref4","first-page":"646","volume-title":"Inflammatory pseudotumor-like follicular dendritic cell tumor of liver and spleen: granulomatous and eosinophil-rich variants mimicking inflammatory or infective lesions","author":"Li","year":"2014"},{"key":"ref5","first-page":"476","volume-title":"Challenges in the diagnosis of EpsteinBarr virus-positive inflammatory follicular dendritic cell sarcoma: extremely wide morphologic spectrum and immunophenotype","author":"Li","year":"2023"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s13000-024-01457-6"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s40792-022-01572-w"},{"key":"ref8","first-page":"245","volume-title":"Inflammatory pseudotumor-like follicular dendritic cell sarcoma of the spleen: a report of six cases with increased IgG4-positive plasma cells","author":"Choe","year":"2013"},{"key":"ref9","first-page":"509","volume-title":"Inflammatory myofibroblastic tumor: comparison of clinicopathologic, histologic, and immunohistochemical features including ALK expression in atypical and aggressive cases","author":"Coffin","year":"2007"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s11899-012-0132-3"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.13105\/wjma.v9.i1.1"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-021-02957-5"}],"container-title":["Journal of Pathology and Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/jpatholtm.org\/upload\/pdf\/jptm-2024-09-27.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/jpatholtm.org\/journal\/view.php?doi=10.4132\/jptm.2024.09.27","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/jpatholtm.org\/upload\/pdf\/jptm-2024-09-27.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T01:00:50Z","timestamp":1741914050000},"score":1,"resource":{"primary":{"URL":"http:\/\/jpatholtm.org\/journal\/view.php?doi=10.4132\/jptm.2024.09.27"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,15]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"URL":"https:\/\/doi.org\/10.4132\/jptm.2024.09.27","relation":{},"ISSN":["2383-7837","2383-7845"],"issn-type":[{"value":"2383-7837","type":"print"},{"value":"2383-7845","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,15]]},"assertion":[{"value":"2024-07-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-31","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-15","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}