{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T03:02:26Z","timestamp":1789441346540,"version":"build-2803163510"},"reference-count":20,"publisher":"The Korean Society of Pathologists and The Korean Society for Cytopathology","issue":"5","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Foundation of Tianjin Science and Technology Bureau","award":["25JCZDJC01080"],"award-info":[{"award-number":["25JCZDJC01080"]}]},{"name":"Foundation of Tianjin Key Medical Discipline Construction Project","award":["TJYXZDXK-3-019C"],"award-info":[{"award-number":["TJYXZDXK-3-019C"]}]},{"name":"Foundation sponsored by Tianjin Health Research Project","award":["TJWJ2025ZK008"],"award-info":[{"award-number":["TJWJ2025ZK008"]}]}],"content-domain":{"domain":["jpatholtm.org"],"crossmark-restriction":true},"short-container-title":["J Pathol Transl Med"],"published-print":{"date-parts":[[2026,9,15]]},"abstract":"<jats:p>Primary cutaneous malignant perivascular epithelioid cell tumors (PEComas) are extremely rare. Accurate diagnosis is critical for prognostic evaluation and guiding clinical management. Here, we report a case of a 19-year-old woman with a 1.1 cm exophytic red mass on her left upper limb. Histological examination revealed a dermal tumor composed of clear cells with prominent nucleoli. The tumor cells displayed cytologic atypia, nuclear pleomorphism, multinucleated giant cells, mitoses and invasive growth, with a multinodular distribution within the dermis and vascular invasion. Immunohistochemically, the tumor cells expressed cathepsin K, HMB45, and CD10. Based on morphological and immunohistochemical findings, we classified it as a primary malignant cutaneous PEComa. To date, only eight reported cases have been described as primary malignant cutaneous PEComas. The present case appears to be the youngest patient reported among all malignant PEComas.<\/jats:p>","DOI":"10.4132\/jptm.2026.05.10","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T06:31:08Z","timestamp":1784529068000},"page":"572-577","update-policy":"https:\/\/doi.org\/10.4132\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinicopathological characteristics of primary malignant cutaneous perivascular epithelioid cell tumor: case report and literature review"],"prefix":"10.4132","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2256-7240","authenticated-orcid":true,"given":"Huaming","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8750-6272","authenticated-orcid":true,"given":"Dan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5052-2283","authenticated-orcid":true,"given":"Shiwu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2611","reference":[{"key":"ref1","first-page":"64","volume-title":"WHO classification of tumours of soft tissue and bone 2013: the main changes compared to the 3rd edition","author":"Zambo","year":"2014"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000173232.22117.37"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2012.01.006"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2007.00842.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.06.041"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13061"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14034"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.5070\/D328157058"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14330"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/dad.0000000000002241"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177\/2632010x231178629"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.20892\/j.issn.2095-3941.2022.0432"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3390\/genes13071153"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/dad.0000000000000465"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/dad.0000000000000054"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/dad.0000000000000041"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.5070\/D3271055626"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/his.12145"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1159\/000510241"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0b013e31815604ab"}],"container-title":["Journal of Pathology and Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/jpatholtm.org\/upload\/pdf\/jptm-2026-05-10.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/jpatholtm.org\/journal\/view.php?doi=10.4132\/jptm.2026.05.10","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/jpatholtm.org\/upload\/pdf\/jptm-2026-05-10.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T02:09:46Z","timestamp":1789438186000},"score":1,"resource":{"primary":{"URL":"http:\/\/jpatholtm.org\/journal\/view.php?doi=10.4132\/jptm.2026.05.10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,15]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"URL":"https:\/\/doi.org\/10.4132\/jptm.2026.05.10","relation":{},"ISSN":["2383-7837","2383-7845"],"issn-type":[{"value":"2383-7837","type":"print"},{"value":"2383-7845","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,15]]},"assertion":[{"value":"2026-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-20","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-15","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}