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Although this personalized approach to medicine has the advantage of maximizing therapeutic effect while limiting toxicity, it can be challenging to implement and expensive. Further, in order to use targeted radionuclide therapy effectively, there is a need for multidisciplinary awareness, education, and collaboration across the scientific, industrial, and medical communities. Even more important, there is a growing understanding that combining radiopharmaceuticals with conventional treatment such as chemotherapy and external beam radiotherapy may limit patient morbidity while improving survival. Developments in radiopharmaceuticals as biomarkers capable of predicting therapeutic response and targeting disease are playing a central role in medical research. Adoption of a practical approach to manufacturing and delivering radiopharmaceuticals, assessing patient eligibility, optimizing post-therapy follow-up, and addressing reimbursement issues will be essential for their success. <\/jats:p>","DOI":"10.4137\/bic.s31804","type":"journal-article","created":{"date-parts":[[2016,5,18]],"date-time":"2016-05-18T22:49:31Z","timestamp":1463611771000},"page":"BIC.S31804","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Targeted Radionuclide Therapy: Practical Applications and Future Prospects"],"prefix":"10.4137","volume":"8s2","author":[{"given":"Katherine","family":"Zukotynski","sequence":"first","affiliation":[{"name":"Departments of Radiology and Medicine, McMaster University, Hamilton, ON, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Jadvar","sequence":"additional","affiliation":[{"name":"Department of Radiology, 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