{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:12:04Z","timestamp":1779289924964,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Med\ufffdInsights\ufffdArthritis\ufffdMusculoskelet Disord"],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the utility of entheseal ultrasonography and serum COMP in the preclinical diagnosis of psoriatic arthritis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>60 psoriatic patients were divided into: 30 patients with psoriasis (group I) and 30 patients with psoriatic arthritis as control (group II). They underwent independent clinical and ultrasonographic examination of both lower limbs at the calcaneal insertions of Achilles tendons. Psoriatic arthritis disease activity and severity was assessed by modified DAS28 and Steinbrockers scores. Serum levels of COMP were measured for all patients by ELISA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>On clinical examination, no entheseal abnormalities were detected in group I while they were present in 23.3% of group II with statistically significant difference between them ( P &lt; 0.001). Ultrasonographic entheseal abnormalities were detected in 33.3% of group I and in 46.7% of group II with no significant difference between them ( P &gt; 0.05). Serum COMP were significantly elevated in group I and II with no statistically significant difference between them (mean \u00b1 SD 5.9 \u00b1 3 and 6.8 \u00b1 12 respectively, P &gt; 0.05). Entheseal ultrasound was more specific (67%) while serum COMP was more sensitive (87%) in the preclinical diagnosis of psoriatic arthritis. Serum COMP levels were significantly correlated with CRP in both groups and with DAS28 and Steinbrockers scores in group II ( P &lt; 0.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Entheseal ultrasonography and serum COMP levels may be used complementary to each other for preclinical diagnosis of psoriatic arthritis. Serum COMP seems to be promising prognostic marker for psoriatic arthritis patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4137\/cmamd.s4461","type":"journal-article","created":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T11:49:31Z","timestamp":1507636171000},"page":"CMAMD.S4461","source":"Crossref","is-referenced-by-count":17,"title":["Value of Entheseal Ultrasonography and Serum Cartilage Oligomeric Matrix Protein in the Preclinical Diagnosis of Psoriatic Arthritis"],"prefix":"10.4137","volume":"3","author":[{"given":"Hanan Mohamed","family":"Farouk","sequence":"first","affiliation":[{"name":"Internal Medicine and Rheumatology, Faculty of Medicine Ain Shams University, Cairo, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afaf Abdel Alim","family":"Mostafa","sequence":"additional","affiliation":[{"name":"Clinical Pathology, Faculty of Medicine Ain Shams University, Cairo, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahar S.","family":"Youssef","sequence":"additional","affiliation":[{"name":"Dermatology and Venereology, Faculty of Medicine Ain Shams University, Cairo, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moataz Mohammed Samy","family":"Elbeblawy","sequence":"additional","affiliation":[{"name":"Radiodiagnosis, Faculty of Medicine Ain Shams University, Cairo, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naglaa Youssef","family":"Assaf","sequence":"additional","affiliation":[{"name":"Rheumatology and Rehabilitation, Faculty of Medicine Ain Shams University, Cairo, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"El Sayed E.","family":"Elokda","sequence":"additional","affiliation":[{"name":"Community Environmental and Occupational Medicine Departments, Faculty of Medicine Ain Shams University, Cairo, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,3,30]]},"reference":[{"key":"bibr1-CMAMD.S4461","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.02.039"},{"key":"bibr2-CMAMD.S4461","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2005.07.009"},{"key":"bibr3-CMAMD.S4461","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.080691"},{"key":"bibr4-CMAMD.S4461","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2008.01216.x"},{"key":"bibr5-CMAMD.S4461","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(03)00127-X"},{"key":"bibr6-CMAMD.S4461","first-page":"137","volume":"35","author":"Scarpa R.","year":"2008","journal-title":"J 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