{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:34:30Z","timestamp":1777397670774,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med\ufffdInsights\ufffdArthritis\ufffdMusculoskelet Disord"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate clinical effectiveness of prednisolone (PSL) and cyclosporin A (CyA), particularly continuous intravenous administration of the latter, in patients with interstitial pneumonia (IP) associated with polymyositis\/dermatomyositis (PM\/DM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We reviewed the clinical findings and therapeutic outcomes of patients with PM\/DM who had received PSL and CyA (PSL + CyA, n = 21 for DM and 2 for PM) or the former alone (n = 12 for DM and 7 for PM). All patients receiving PSL + CyA had active IP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifteen of the 21 DM patients receiving PSL + CyA showed favorable therapeutic outcomes of IP (recovery group), while the remaining 6 died of respiratory failure (death group). Before treatment PaO\n                      <jats:sub>2<\/jats:sub>\n                      in room air and %VC were significantly lower, and the total CT score was significantly higher in the death group than in the recovery one. Continuous intravenous administration of CyA was performed in 6 patients for severe IP requiring oxygen therapy, and of these 2 showed complete recovery from it.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Coadministration of PSL and CyA, particularly continuous intravenous infusion of the latter, from the early phase of illness may be a potent therapeutic option for PM\/DM patients with decreases in PaO\n                      <jats:sub>2<\/jats:sub>\n                      and %VC and\/or a high total CT score suggestive of a poor prognosis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4137\/cmamd.s9398","type":"journal-article","created":{"date-parts":[[2012,3,14]],"date-time":"2012-03-14T16:18:41Z","timestamp":1331741921000},"page":"CMAMD.S9398","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Coadministration of Cyclosporin a with Prednisolone in Acute Interstitial Pneumonia Complicating Polymyositis\/Dermatomyositis"],"prefix":"10.4137","volume":"5","author":[{"given":"Yasuhiro","family":"Shimojima","sequence":"first","affiliation":[{"name":"Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wataru","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagaaki","family":"Katoh","sequence":"additional","affiliation":[{"name":"Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ko-ichi","family":"Tazawa","sequence":"additional","affiliation":[{"name":"Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Sekijima","sequence":"additional","affiliation":[{"name":"Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-ichi","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,3,14]]},"reference":[{"key":"bibr1-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14368-1"},{"key":"bibr2-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2003.017715"},{"key":"bibr3-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.47.0967"},{"key":"bibr4-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1186\/ar2139"},{"key":"bibr5-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1843.1999.00179.x"},{"key":"bibr6-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.2002.01933.x"},{"key":"bibr7-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-001-0146-y"},{"key":"bibr8-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.42.1253"},{"key":"bibr9-CMAMD.S9398","first-page":"1527","volume":"26","author":"Nawata Y.","year":"1999","journal-title":"J Rheumatol."},{"key":"bibr10-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200011000-00005"},{"key":"bibr11-CMAMD.S9398","first-page":"58","volume":"32","author":"Fujisawa T.","year":"2005","journal-title":"J Rheumatol."},{"key":"bibr12-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197502132920706"},{"key":"bibr13-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.10.041"},{"key":"bibr14-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2004.04.003"},{"key":"bibr15-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2007.01.023"},{"key":"bibr16-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1053\/sarh.2002.50012"},{"key":"bibr17-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-007-0553-3"},{"key":"bibr18-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1080\/08916930500124023"},{"key":"bibr19-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90381-3"},{"key":"bibr20-CMAMD.S9398","first-page":"1719","volume":"32","author":"Kameda H.","year":"2005","journal-title":"J Rheumatol."},{"key":"bibr21-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.07.094"},{"key":"bibr22-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.02.076"},{"key":"bibr23-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2005.02680.x"},{"key":"bibr24-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200303000-00005"},{"key":"bibr25-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21087"},{"key":"bibr26-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1097\/00054725-200403000-00002"},{"key":"bibr27-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1002\/art.21023"},{"key":"bibr28-CMAMD.S9398","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq073"}],"container-title":["Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.4137\/CMAMD.S9398","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.4137\/CMAMD.S9398","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.4137\/CMAMD.S9398","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:11:29Z","timestamp":1777371089000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.4137\/CMAMD.S9398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":28,"alternative-id":["10.4137\/CMAMD.S9398"],"URL":"https:\/\/doi.org\/10.4137\/cmamd.s9398","relation":{},"ISSN":["1179-5441","1179-5441"],"issn-type":[{"value":"1179-5441","type":"print"},{"value":"1179-5441","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}