{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:49:25Z","timestamp":1777499365160,"version":"3.51.4"},"reference-count":45,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Cardiol"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Balloon valvuloplasty was established as an alternative to surgery for treatment of aortic valve stenosis in childhood. Acute complications after balloon dilatation including aortic insufficiency or early death were described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim of Work<\/jats:title>\n                    <jats:p>To analyze early outcome and midterm results of balloon aortic valvuloplasty (BAV) in Children's Hospital, Mansoura University, Egypt.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>Between April 2005\u2013June 2008, all consecutive patients of age &lt;18 years treated for aortic valve stenosis (AVS) with BAV were analyzed retrospectively. The study included 21 patients; 17 males, and 4 females. Their age ranged from the neonatal period to 10 years (mean age 5.6 \u00b1 3.7 years). Patients with gradient \u226550 mmHg and aortic valve insufficiency (AI) up to grade I were included. All patients had isolated aortic valve stenosis except 3 patients (14.3%) had associated aortic coarctation. Six patients (28.6%) had bicuspid aortic valve. All patients had normal myocardial function except one (4.8%) had FS 15%. The duration of follow up was (mean \u00b1 SD: 18.5 \u00b1 11.7 months).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Femoral artery approach was used in 20 patients (95.2%) and carotid artery in one neonate (4.8%). Balloon\/annulus ratio was 0.83 \u00b1 0.04. Significant reduction in pressure gradient was achieved (mean 66.7 \u00b1 9.8 mmHg to 20.65 \u00b1 2.99 mmHg) ( P &lt; 0.001). Nine patients (42.8%) developed grade I AI, 2 patients (9.5%) developed grade II AI and 1 patient (4.8%) developed grade III AI. Two early deaths (9.5%); one died due to heart failure caused by grade IV AI and a neonate died because of severely compromised LV function. One patient (4.8%) had femoral artery occlusion necessitating anticoagulation. Patients remained free from re-intervention during follow up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Balloon valvuloplasty of aortic valve stenosis significantly reduces gradient with low morbidity and mortality in children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4137\/cmc.s8602","type":"journal-article","created":{"date-parts":[[2012,2,21]],"date-time":"2012-02-21T15:25:09Z","timestamp":1329837909000},"page":"CMC.S8602","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Balloon Valvuloplasty of Aortic Valve Stenosis in Childhood: Midterm Results in a Children's Hospital, Mansoura University, Egypt"],"prefix":"10.4137","volume":"6","author":[{"given":"Hala Al","family":"Marshafawy","sequence":"first","affiliation":[{"name":"Pediatric Cardiology Unit, Children's Hospital, Mansoura University, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gehan Attia Al","family":"Sawah","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit, Children's Hospital, Mansoura University, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"Hafez","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit, Children's Hospital, Mansoura University, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Matter","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit, Children's Hospital, Mansoura University, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adel El","family":"Gamal","sequence":"additional","affiliation":[{"name":"Pediatric Cardiac surgery Unit, Children's Hospital, Mansoura University, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdel Gawad","family":"Sheishaa","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit, Children's Hospital, Mansoura University, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdy Abu El","family":"Kair","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit, Children's Hospital, Mansoura University, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,2,21]]},"reference":[{"key":"bibr1-CMC.S8602","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-002-0205-5"},{"key":"bibr2-CMC.S8602","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-006-1415-z"},{"key":"bibr3-CMC.S8602","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00608-7"},{"key":"bibr4-CMC.S8602","first-page":"661","volume":"196","author":"Ewert P.","year":"2007","journal-title":"Clin Res 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