{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T09:22:03Z","timestamp":1777195323439,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Jpn Clin Med"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:p> The number of patients with late-onset myasthenia gravis (MG) among patients \u226550 years has been increasing recently. We encountered three patients who developed elderly-onset MG at a particularly advanced age (\u226580 years). All were female and positive for anti-acetylcholine receptor antibodies. About 4 years have passed since MG onset in all three patients and symptoms have been controlled without recurrence using a combination of oral low-dose prednisolone and tacrolimus. As many cases of elderly-onset MG do not require strong immunosuppression, we recommend minimum immunosuppressive treatment to avoid adverse events, particularly in patients at an advanced age of \u226580 years. <\/jats:p>","DOI":"10.4137\/jcm.s29601","type":"journal-article","created":{"date-parts":[[2015,7,23]],"date-time":"2015-07-23T21:51:17Z","timestamp":1437688277000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Treatment of Myasthenia Gravis in Patients with Elderly Onset at Advanced Age"],"prefix":"10.4137","volume":"6","author":[{"given":"Noriko","family":"Nishikawa","sequence":"first","affiliation":[{"name":"Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Shitsukawa Tohon, Ehime, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Nagai","sequence":"additional","affiliation":[{"name":"Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Shitsukawa Tohon, Ehime, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoaki","family":"Tsujii","sequence":"additional","affiliation":[{"name":"Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Shitsukawa Tohon, Ehime, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Win T.","family":"Kyaw","sequence":"additional","affiliation":[{"name":"Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Shitsukawa Tohon, Ehime, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nachi","family":"Tanabe","sequence":"additional","affiliation":[{"name":"Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Shitsukawa Tohon, Ehime, 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