{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:40:01Z","timestamp":1777891201986,"version":"3.51.4"},"reference-count":40,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmol Eye Dis"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Glaucoma is a public health issue worldwide, particularly in Africa. In Cameroon, the prevalence rate of primary open-angle glaucoma (POAG) ranges between 4.5% and 8.2%. Helicobacter pylori (HP) has been implicated in digestive and extra-digestive diseases, including glaucoma. The objective of this work was to evaluate the implication of CagA- and VacA-positive strains of HP in POAG using a case-control design.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An analytical study was conducted from October 2013 to December 2013. Participants were recruited in eye care centers in Yaound\u00e9. Enzyme-linked immunosorbent assays (ELISAs) were carried out in the La Grace Laboratory in Yaound\u00e9.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The total sample consisted of 50 POAG patients and 31 controls with a mean age of 58.5 \u00b1 12.2 years and 45.5 \u00b1 14.6 years, respectively. The prevalence rates of HP in the POAG and control groups were 74% (37\/50) and 87% (27\/31), respectively ( P = 0.125). The prevalence rates of CagA-positive HP seropositivity in the POAG and control groups were 26% and 22.58%, respectively ( P = 0.47), and the prevalence rates of VacA-positive HP participants were 6% and 0%, respectively ( P = 0.22).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The HP prevalence rates among POAG patients and controls were 74% and 87%, respectively. There was no significant difference between prevalence rates of HP in the POAG and control groups. There was no association between POAG and CagA- or VacA-positive HP infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4137\/oed.s35895","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T15:21:47Z","timestamp":1455722507000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["No Association between CagA- and VacA-Positive Strains of\n                    <i>Helicobacter Pylori<\/i>\n                    and Primary Open-Angle Glaucoma: A Case\u2013Control Study"],"prefix":"10.4137","volume":"8","author":[{"given":"C. Domngang","family":"Noche","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, Universit\u00e9 des Montagnes, Bangangt\u00e9, Cameroon."},{"name":"Faculty of Sciences, Department of Microbiology, Universit\u00e9 de Yaound\u00e9 I, Yaound\u00e9, Cameroon."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Njajou","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Universit\u00e9 des Montagnes, Bangangt\u00e9, Cameroon."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. X.","family":"Etoa","sequence":"additional","affiliation":[{"name":"Faculty of Sciences, Department of Microbiology, Universit\u00e9 de Yaound\u00e9 I, Yaound\u00e9, Cameroon."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,2,17]]},"reference":[{"key":"bibr1-OED.S35895","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2011-300539"},{"key":"bibr2-OED.S35895","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.081224"},{"issue":"11","key":"bibr3-OED.S35895","first-page":"844","volume":"82","author":"Resnikoff S.","year":"2004","journal-title":"Bull World Health Organ."},{"issue":"2","key":"bibr4-OED.S35895","first-page":"83","volume":"16","author":"Ellong A.","year":"2006","journal-title":"Cahiers Sant\u00e9."},{"key":"bibr5-OED.S35895","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-009-1166-7"},{"key":"bibr6-OED.S35895","first-page":"299","volume":"20","author":"Hunt R.H.","year":"2011","journal-title":"J 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