{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:03:33Z","timestamp":1791644613180,"version":"4.3.4"},"reference-count":53,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmol Eye Dis"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p>AzaSite\u00ae (azithromomycin 1.0%) ophthalmic solution was approved in 2007 by the US Food and Drug Administration (FDA) as the first commercially available formulation of ophthalmic azithromycin for the treatment of bacterial conjunctivitis. AzaSite\u00ae utilizes a vehicle delivery system called DuraSite\u00ae, which stabilizes and sustains the release of azithromycin to the ocular surface, leading to a longer drug residence time, less frequent dosing, and an increase in patient compliance. AzaSite\u00ae is a broad spectrum antibiotic, effective against Gram-positive, Gram-negative, and atypical bacteria. AzaSite\u00ae has been studied for the treatment of ocular conditions beyond its clinical indication. A number of clinical studies have evaluated its efficacy and safety in the management of ocular conditions such as bacterial conjunctivitis and blepharitis on both the pediatric and adult populations. This article aims to evaluate the peer-reviewed published literature on the use of azithromycin 1.0% ophthalmic for current and possible future ophthalmic uses.<\/jats:p>","DOI":"10.4137\/oed.s7791","type":"journal-article","created":{"date-parts":[[2012,2,23]],"date-time":"2012-02-23T15:58:44Z","timestamp":1330012724000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":34,"title":["Review of Azithromycin Ophthalmic 1% Solution (AzaSite\u00ae) for the Treatment of Ocular Infections"],"prefix":"10.4137","volume":"4","author":[{"given":"Dominick L.","family":"Opitz","sequence":"first","affiliation":[{"name":"Illinois College of Optometry, Department of Clinical Education, 3241 South Michigan Avenue, Chicago, Illinois 60616, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer S.","family":"Harthan","sequence":"additional","affiliation":[{"name":"Illinois College of Optometry, Department of 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