{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T01:19:17Z","timestamp":1778721557122,"version":"3.51.4"},"reference-count":13,"publisher":"American Society of Consultant Pharmacists","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["sr care pharm"],"published-print":{"date-parts":[[2021,10,1]]},"abstract":"Objective:<\/jats:bold> To identify the dietary supplements most commonly promoted online for brain health and to compare their major ingredients over 18 months. Mild cognitive impairment and Alzheimer\u2019s disease are increasing globally with few effective treatments available. Dietary\n supplements are widely promoted in the media and online for brain health and memory improvement despite minimal evidence of an actual effect. Methods:<\/jats:bold> Incognito mode on Google Chrome was used to conduct four separate searches using the terms: memory supplement, brain health\n supplement, Alzheimer\u2019s supplement, and dementia supplement. The four separate searches for products were conducted through CVS, Walgreens, Walmart, GNC, Amazon, Yahoo, and Google. For each website, the top 10 supplement products and their ingredients were documented in August 2017 and\n again in January 2019. Results:<\/jats:bold> Of the four terms used, \u201cmemory supplement\u201d and \u201cbrain health supplement\u201d provided the most results. The most common products were Prevagen\u00ae, Procera\u00ae, and Neuro Health\u00ae. Amazon had the most repeated products\n in 2017 and 2019, while Google and CVS had the least. Focus Factor\u00ae appeared 11 times in 2019 compared with once in 2017. At both time points, the most commonly promoted products were proprietary blends of Ginkgo biloba, vitamins, particularly vitamin B12 and folic acid, huperzine-A, Bacopa\n monnieri, and phosphatidylserine. Conclusions:<\/jats:bold> Though the 2017 and 2019 datasets showed diverse products, the primary ingredients were similar. These supplements have insufficient evidence of efficacy and are expensive. Health professionals must be knowledgeable about dietary\n supplements for brain health to appropriately counsel individuals.<\/jats:p>","DOI":"10.4140\/tcp.n.2021.489","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T04:59:33Z","timestamp":1633064373000},"page":"489-492","source":"Crossref","is-referenced-by-count":3,"title":["Online Promotion of \u201cBrain Health\u201d Supplements"],"prefix":"10.4140","volume":"36","author":[{"given":"Brittany R.","family":"Block","sequence":"first","affiliation":[{"name":"1University of Rhode Island, Kingston, Rhode Island."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah G.","family":"Albanese","sequence":"additional","affiliation":[{"name":"2Rhode Island Hospital, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne L.","family":"Hume","sequence":"additional","affiliation":[{"name":"1University of Rhode Island, Kingston, Rhode Island."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2625","reference":[{"key":"ref1","first-page":"2021","article-title":"Alzheimer\u2019s Disease Facts and Figures.","volume":"17","year":"2020","journal-title":"Published March"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"656","DOI":"10.7326\/M19-3887","article-title":"Benefits and harms of prescription drugs and supplements for treatment of clinical Alzheimer-type dementia.","volume":"172","year":"2020","journal-title":"Ann Intern Med"},{"key":"ref3","first-page":"2019","volume":"5","year":"2019","journal-title":"Published February"},{"key":"ref4","first-page":"e284","article-title":"Defining optimal brain health in adults: a presidential advisory from the American Heart Association\/American Stroke Association.","volume":"48","year":"2017","journal-title":"Stroke"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"52","DOI":"10.7326\/M17-1530","article-title":"Over-the-counter supplement interventions to prevent cognitive decline, mild cognitive impairment, and clinical Alzheimer-type dementia: a systematic review.","volume":"168","year":"2018","journal-title":"Ann Intern Med"},{"key":"ref6","first-page":"2020","article-title":"AARP Brain Health and Dietary Supplements Survey.","volume":"2","year":"2019","journal-title":"Accessed October"},{"key":"ref7","article-title":"Five unapproved drugs found in cognitive enhancement supplements.","journal-title":"Neurology"},{"key":"ref8","first-page":"2017","volume":"12","year":"2024","journal-title":"Published Septmeber"},{"issue":"1","key":"ref9","first-page":"4","article-title":"Effects of a supplement containing apoaequorin on verbal learning in older people in the community.","volume":"30","year":"2016","journal-title":"Adv Mind Body Med"},{"key":"ref10","article-title":"Americans Took Prevagen for Years \u2013 as the FDA Questioned Its Safety.","year":"2021"},{"key":"ref11","first-page":"2020","article-title":"Vinpocetine in Dietary Supplements.","volume":"2","year":"2019","journal-title":"Accessed October"},{"key":"ref12","article-title":"Vinpocetine for cognitive impairment and dementia.","year":"2003","journal-title":"Cochrane Database Syst Review"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1176\/ajp.138.7.970","article-title":"Double-blind trial of 2-dimethylaminoethanol in Alzheimer\u2019s disease.","volume":"138","year":"1981","journal-title":"Am J Psychiatry."}],"container-title":["The Senior Care Pharmacist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/ascp\/tscp\/2021\/00000036\/00000010\/art00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T05:00:47Z","timestamp":1634014847000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.4140\/TCP.n.2021.489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,1]]},"references-count":13,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10,1]]}},"alternative-id":["2639-9636(20211001)36:10L.489;1-"],"URL":"https:\/\/doi.org\/10.4140\/tcp.n.2021.489","relation":{},"ISSN":["2639-9636"],"issn-type":[{"value":"2639-9636","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10,1]]}}}