{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T14:20:19Z","timestamp":1771510819519,"version":"3.50.1"},"reference-count":13,"publisher":"American Society of Consultant Pharmacists","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["sr care pharm"],"published-print":{"date-parts":[[2025,3,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> In recent years, aspirin use has been controversial for primary prevention of atherosclerotic cardiovascular disease (ASCVD) events. Numerous clinical trials have proven that aspirin does not improve outcomes and increases major bleeding rates. Despite clinical\n trial data and guideline recommendations, there remains a large number of older adults taking aspirin for primary prevention.  <jats:bold>Objective:<\/jats:bold> Describe the impact that pharmacists had on the discontinuation of inappropriately prescribed aspirin in a geriatric primary care clinic.\n  <jats:bold>Methods:<\/jats:bold> This is a retrospective review of patients taking aspirin. A report was generated for all patients with aspirin on their medication list. The pharmacist determined the indication for aspirin. If patients were taking aspirin for primary prevention, the pharmacist recommended\n aspirin be discontinued.  <jats:bold>Results:<\/jats:bold> A total of 528 patients were included in this study. There were 321 (61%) females and 207 (39%) males. After analyzing aspirin indication, 122 (48%) were taking aspirin for primary prevention, 273 (52%) were taking aspirin for secondary\n prevention, and 133 (52%) were taking aspirin for another indication. The recommendation to discontinue aspirin was accepted 91 times and declined 30 times, yielding a 75% acceptance rate.  <jats:bold>Conclusion:<\/jats:bold> Aspirin has several appropriate indications for use; however, previous\n studies have shown that risk outweighs benefit when used for primary prevention of ASCVD events in the geriatric population. When aspirin is on a patient\u2019s medication list, it should be assessed routinely for appropriateness. This retrospective review by pharmacists highlights the need\n for review and discontinuation of aspirin when appropriate.<\/jats:p>","DOI":"10.4140\/tcp.n.2025.145","type":"journal-article","created":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T09:37:54Z","timestamp":1740735474000},"page":"145-149","source":"Crossref","is-referenced-by-count":1,"title":["Pharmacists\u2019 Intervention in Inappropriate Aspirin Prescribing in a Geriatric Primary Care Clinic"],"prefix":"10.4140","volume":"40","author":[{"given":"Paige","family":"Tulcewicz","sequence":"first","affiliation":[{"name":"HCA Florida North Florida Hospital, Outpatient Pharmacy, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly","family":"Atkinson","sequence":"additional","affiliation":[{"name":"HCA Florida North Florida Hospital, Outpatient Pharmacy, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Koff","sequence":"additional","affiliation":[{"name":"HCA Florida North Florida Hospital, Outpatient Pharmacy, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl","family":"Smith","sequence":"additional","affiliation":[{"name":"HCA Florida North Florida Hospital, Outpatient Pharmacy, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2625","reference":[{"issue":"5","key":"ref1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.3949\/ccjm.87a.19045","article-title":"Aspirin for primary prevention of atherosclerotic cardiovascular events.","volume":"87","year":"2020","journal-title":"CCJM."},{"issue":"16","key":"ref2","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1056\/NEJMoa1805819","article-title":"Effect of aspirin on cardiovascular events and bleeding in the healthy elderly.","volume":"379","year":"2018","journal-title":"N Engl J Med."},{"key":"ref3","article-title":"Aspirin in Reducing Events in the Elderly. American College of Cardiology.","year":"2023"},{"key":"ref4","article-title":"Archived: Aspirin for the Prevention of Cardiovascular Disease: Preventive Medication | United States Preventive Services Taskforce.","year":"2023"},{"issue":"16","key":"ref5","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1056\/NEJMoa1803955","article-title":"Effect of aspirin on all-cause mortality in the healthy elderly.","volume":"379","year":"2018","journal-title":"N Engl J Med."},{"issue":"16","key":"ref6","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1056\/NEJMoa1804988","article-title":"Study Collaborative Group. Effects of aspirin for primary prevention in persons with diabetes mellitus.","volume":"379","year":"2018","journal-title":"N Engl J Med."},{"issue":"10152","key":"ref7","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/S0140-6736(18)31924-X","article-title":"Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.","volume":"392","year":"2018","journal-title":"The Lancet."},{"key":"ref8","article-title":"ACC\/AHA guideline on the primary prevention of cardiovascular disease: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines.","year":"2019","journal-title":"Circulation."},{"issue":"16","key":"ref9","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1001\/jama.2022.4983","article-title":"Aspirin use to prevent cardiovascular disease: us preventive services task force recommendation statement.","volume":"327","year":"2022","journal-title":"JAMA"},{"issue":"4","key":"ref10","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/jgs.15767","article-title":"updated AGS Beers Criteria\u00ae for potentially inappropriate medication use in older adults.","volume":"67","year":"2019","journal-title":"J Am Geriatr Soc."},{"key":"ref11","article-title":"Aging and Medications\u2014Older People\u2019s Health Issues.","year":"2024","journal-title":"Merck Manual Consumer Version."},{"key":"ref12","first-page":"2024","volume":"30","year":"2023","journal-title":"Accessed May"},{"key":"ref13","first-page":"2024","article-title":"National and Regional Projections of Supply and Demand for Primary Care Practitioners: 2013-2025.","volume":"30","year":"2016","journal-title":"Accessed May"}],"container-title":["The Senior Care Pharmacist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/ascp\/tscp\/2025\/00000040\/00000003\/art00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T20:14:54Z","timestamp":1741810494000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.4140\/TCP.n.2025.145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,1]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3,1]]}},"alternative-id":["2639-9636(20250301)40:3L.145;1-"],"URL":"https:\/\/doi.org\/10.4140\/tcp.n.2025.145","relation":{},"ISSN":["2639-9636"],"issn-type":[{"value":"2639-9636","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,1]]}}}