{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:30:34Z","timestamp":1787031034656,"version":"build-2736575974"},"reference-count":33,"publisher":"Korean Cancer Association","issue":"1","license":[{"start":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T00:00:00Z","timestamp":1561420800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["06-2016-2920"],"award-info":[{"award-number":["06-2016-2920"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002551","name":"Seoul National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002551","id-type":"DOI","asserted-by":"publisher"}]},{"name":"SNUH Research Fund","award":["03-2017-0100"],"award-info":[{"award-number":["03-2017-0100"]}]}],"content-domain":{"domain":["e-crt.org"],"crossmark-restriction":true},"short-container-title":["Cancer Res Treat"],"published-print":{"date-parts":[[2020,1,15]]},"DOI":"10.4143\/crt.2019.183","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T07:37:03Z","timestamp":1561448223000},"page":"149-166","update-policy":"https:\/\/doi.org\/10.4143\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Therapeutic Co-targeting of WEE1 and ATM Downregulates PD-L1 Expression in Pancreatic Cancer"],"prefix":"10.4143","volume":"52","author":[{"given":"Mei Hua","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ah-Rong","family":"Nam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Eun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju-Hee","family":"Bang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung-Jue","family":"Bang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do-Youn","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2954","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nature16965"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2015.226"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.10.040"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-16-3565"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.2728"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1706392114"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-3229"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2016.06.006"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0014-x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2016.04.014"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.07.012"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/nature23643"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2014.06.003"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12099"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01883-9"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-16-3215"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3390\/cancers6010240"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2010.07919.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3109\/07357907.2014.898156"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21783"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2011.11.013"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2015.03.001"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms12632"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-018-0114-z"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5813292"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.07270"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-2825"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2014.329"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S156582"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.04.031"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2017.1423170"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-018-0161-x"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2017.356"}],"container-title":["Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-crt.org\/upload\/pdf\/crt-2019-183.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-crt.org\/journal\/view.php?doi=10.4143\/crt.2019.183","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-crt.org\/upload\/pdf\/crt-2019-183.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,12]],"date-time":"2020-01-12T23:21:33Z","timestamp":1578871293000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-crt.org\/journal\/view.php?doi=10.4143\/crt.2019.183"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,15]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"URL":"https:\/\/doi.org\/10.4143\/crt.2019.183","relation":{},"ISSN":["1598-2998","2005-9256"],"issn-type":[{"value":"1598-2998","type":"print"},{"value":"2005-9256","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,15]]},"assertion":[{"value":"2019-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-25","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-15","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}