{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T19:43:28Z","timestamp":1793648608816,"version":"4.5.1"},"reference-count":36,"publisher":"Korean Cancer Association","issue":"1","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["e-crt.org"],"crossmark-restriction":true},"short-container-title":["Cancer Res Treat"],"published-print":{"date-parts":[[2023,1,15]]},"abstract":"<jats:p>Purpose This study aimed to estimate the risk of cancer incidence and mortality according to adherence to lifestyle-related cancer prevention guidelines.Materials and Methods Men and women who participated in the general health screening program in 2002 and 2003 provided by the National Health Insurance Service were included (n=8,325,492). Self-reported smoking, alcohol consumption, and physical activity habits and directly measured body mass index were collected. The participants were followed up until the date of cancer onset or death or 31 December 2018. The Cox proportional hazard model was used to evaluate the hazard ratio (HR) for cancer incidence and mortality according to different combinations of lifestyle behaviors.Results Only 6% of men and 15% of women engaged in healthy behavior at baseline, such as not smoking, not drinking alcohol, being moderately or highly physically active, and within a normal body mass index range. Compared to the best combination of healthy lifestyle behaviors, the weak and moderate associations with increased all cancer incidence (HR &lt; 1.7) and mortality (HR &lt; 2.5) were observed in those with heavy alcohol consumption and in former or current smokers. HRs of cancer mortality were significantly increased among current smokers in most combinations.Conclusion Compared to full adherence to cancer prevention recommendations, unhealthy behaviors increase cancer risk. As few people meet these recommendations, there is a great opportunity for cancer prevention.<\/jats:p>","DOI":"10.4143\/crt.2021.1031","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T22:38:31Z","timestamp":1647902311000},"page":"15-27","update-policy":"https:\/\/doi.org\/10.4143\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Adherence to Cancer Prevention Guidelines and Cancer Incidence and Mortality: A Population-Based Cohort Study"],"prefix":"10.4143","volume":"55","author":[{"given":"Jin-Kyoung","family":"Oh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minji","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byungmi","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Young","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2954","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(05)67725-2"},{"key":"ref2","first-page":"S1","volume-title":"European Code against Cancer 4th edition: 12 ways to reduce your cancer risk","author":"Schuz","year":"2015"},{"key":"ref3","volume-title":"Continuous update project expert report 2018","year":"2018"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21591"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-020-0806-x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.114.094854"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.epi-16-0121"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2021.291"},{"key":"ref9","volume-title":"Lifestyle habits have a major impact on cancer","year":"1991"},{"key":"ref10","volume-title":"First step to cancer prevention, follow the code against cancer [Internet]","year":"2006"},{"key":"ref11","volume-title":"Avoid alcohol consumption! 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