{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:15:57Z","timestamp":1792790157728,"version":"4.5.0"},"reference-count":30,"publisher":"Korean Cancer Association","issue":"2","license":[{"start":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T00:00:00Z","timestamp":1626048000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2015R1C1A2A01053357"],"award-info":[{"award-number":["2015R1C1A2A01053357"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Science, Informatics, Communication and Technology"}],"content-domain":{"domain":["e-crt.org"],"crossmark-restriction":true},"short-container-title":["Cancer Res Treat"],"published-print":{"date-parts":[[2022,4,15]]},"abstract":"<jats:p>PurposeWe aimed to develop a prognostic model to assist palliative care referral at least 3 months before death in advanced cancer patients treated at an outpatient medical oncology clinic.Materials and MethodsIn this prospective cohort study, a total of 200 patients were enrolled at a tertiary cancer center in South Korea. The major eligibility criterion was an expected survival of less than a year as estimated by their oncologists. We analyzed the influences of known prognostic factors along with chemotherapy status, mid-arm circumference, and triceps skinfold thickness on survival time.  ResultsThe mean age of the patients was 64.5 years, 36% were female, and the median survival time was 7.6 months. In the multivariate analysis, we found 6 significant factors related to poor survival: a poor Eastern Cooperative Oncology Group (ECOG) performance status (\u22652), not undergoing chemotherapy, anorexia, a low lymphocyte level (&lt;12%), a high lactate dehydrogenase (LDH) level (\u2265300 IU\/L), and a low mid-arm circumference (&lt;23 cm). We developed a prognostic model (score, 0-8.0) to predict 3-month survival based on the multivariate analysis. Patients who scored \u22654.0 points had a short survival of less than 3 months (p&lt;0.001). The discriminating ability of the prognostic model using the area under the receiver operating characteristic curve (AUC) was 0.88. ConclusionThe prognostic model using ECOG performance status, chemotherapy status, anorexia, lymphocytes, LDH, and mid-arm circumference can predict 3-month survival in medical oncology outpatients. It can alert oncologists to refer patients to palliative care specialists before it is too late.<\/jats:p>","DOI":"10.4143\/crt.2021.483","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T20:45:29Z","timestamp":1626122729000},"page":"621-629","update-policy":"https:\/\/doi.org\/10.4143\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Prognostic Model to Facilitate Palliative Care Referral in Oncology Outpatients"],"prefix":"10.4143","volume":"54","author":[{"given":"Yu Jung","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Hiratsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Yeon","family":"Suh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beodeul","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si Won","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Yup","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koung Jin","family":"Suh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Won","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Won","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keun-Wook","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jee Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Seok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2954","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1198"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1000678"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(13)62416-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2016.70.1474"},{"key":"ref5","volume-title":"","year":"2020"},{"key":"ref6","volume-title":"","author":"Hospice","year":"2016"},{"key":"ref7","volume-title":"","year":"2020"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2015-0234"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2012-0192"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28628"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2018-0094"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32782"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2012.0147"},{"key":"ref14","first-page":"560","volume-title":"Standard values for nutritional assessment by anthropometry in healthy Korean adults","author":"Cho","year":"1999"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.21037\/apm-20-270"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33151"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1177\/082585979601200102"},{"key":"ref18","first-page":"231","volume-title":"A new palliative prognostic score: a first step for the staging of terminally ill cancer patients. 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