{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:16:11Z","timestamp":1792790171972,"version":"4.5.0"},"reference-count":34,"publisher":"Korean Cancer Association","issue":"4","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2022R1A2C1004608"],"award-info":[{"award-number":["2022R1A2C1004608"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Science and ICT","id":[{"id":"https:\/\/ror.org\/01wpjm123","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["e-crt.org"],"crossmark-restriction":true},"short-container-title":["Cancer Res Treat"],"published-print":{"date-parts":[[2026,10,15]]},"abstract":"<jats:p>PurposeThe incidence, prevalence, and survival rates of gastric cancer are high, and the prognostic effects of healthy behaviors among survivors have not been well investigated. Therefore, we aimed to assess the effects of postdiagnosis healthy behaviors and behavior changes after gastric cancer diagnosis on all-cause mortality.Materials and MethodsAs a population-based retrospective cohort study, we used a cancer public library sample DB of gastric cancer patients between 2012 and 2019. Information from regular health check-up examinations was used to investigate their anthropometric measures, physical activities, alcohol consumption, and smoking status before and after cancer diagnosis. Hazard ratios (HRs) for all-cause deaths with 95% confidence intervals (CIs) were estimated via the Cox proportional hazards model.ResultsWe analyzed 9,717 gastric cancer patients and 5,929 of those as a subgroup to assess the effects of behavior changes. Reduced mortality was shown among cancer patients who met the recommended criteria after the cancer diagnosis for physical activity (adjusted HR, 0.67 [95% CI, 0.49 to 0.93], mean frequencies of moderate to vigorous physical activity per week: \u2265 5 days vs. 0 days) and smoking cessation (0.77 [0.61 to 0.97], smoking status: never-smokers vs. current smokers). Participants who reported enhancement in behaviors had significantly lower mortality than the others who reported no or limited changes in physical activity (0.73 [0.55 to 0.96]) and smoking status (0.56 [0.38 to 0.83]).ConclusionThe current study highlights the advantages of physical activity and smoking cessation in reducing mortality, and these benefits are even greater when patients improve their behavior after cancer diagnosis.<\/jats:p>","DOI":"10.4143\/crt.2025.177","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T04:29:12Z","timestamp":1756873752000},"page":"1287-1297","update-policy":"https:\/\/doi.org\/10.4143\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Healthy Behaviors and All-Cause Mortality among Korean Gastric Cancer Survivors"],"prefix":"10.4143","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1832-4210","authenticated-orcid":true,"given":"Donghyun","family":"Won","sequence":"first","affiliation":[{"name":"Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea"},{"name":"Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeeyoo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sooyoung","family":"Cho","sequence":"additional","affiliation":[{"name":"Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Yoon","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea"},{"name":"Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyuk-Joon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery, Seoul National University College of Medicine, Seoul, Korea"},{"name":"Cancer Research Institute, Seoul National University, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6426-1969","authenticated-orcid":true,"given":"Aesun","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea"},{"name":"Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul, Korea"},{"name":"Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea"},{"name":"Cancer Research Institute, Seoul National University, Seoul, Korea"},{"name":"Interdisciplinary Program in Cancer Biology Major, Seoul National University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2954","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834","type":"journal-article"},{"key":"ref2","volume-title":"The benefit from National Cancer Screening Program for gastric cancer: the Korean National Health Insurance Big Data analysis","author":"Suh","type":"conference-paper"},{"key":"ref3","first-page":"42","volume-title":"The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease study 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