{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:49:50Z","timestamp":1790815790279,"version":"4.1.0"},"reference-count":115,"publisher":"Informa UK Limited","issue":"12","funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","award":["AI56168, AI100631, AI116420"],"award-info":[{"award-number":["AI56168, AI100631, AI116420"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Future Med. Chem."],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.4155\/fmc-2016-0053","type":"journal-article","created":{"date-parts":[[2016,8,9]],"date-time":"2016-08-09T10:26:18Z","timestamp":1470738378000},"page":"1469-1484","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":86,"title":["Sphingolipids as Targets for Treatment of Fungal Infections"],"prefix":"10.1080","volume":"8","author":[{"given":"Rodrigo","family":"Rollin-Pinheiro","sequence":"first","affiliation":[{"name":"Departamento de Microbiologia Geral, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, UFRJ, 21941-902 Rio de Janeiro, Brazil"},{"name":"Department of Molecular Genetics & Microbiology, Stony Brook University, 145 Life Sciences Building, Stony Brook, 11794NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashutosh","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics & Microbiology, Stony Brook University, 145 Life Sciences Building, Stony Brook, 11794NY, USA"},{"name":"Veterans Administration Medical Center, Northport, 11768NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliana","family":"Barreto-Bergter","sequence":"additional","affiliation":[{"name":"Departamento de Microbiologia Geral, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, UFRJ, 21941-902 Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Del Poeta","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics & Microbiology, Stony Brook University, 145 Life Sciences Building, Stony Brook, 11794NY, USA"},{"name":"Veterans Administration Medical Center, Northport, 11768NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,8,9]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa022139"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/322606"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004404"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki218"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1562890"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/713687"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a019703"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1835"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.1.28-39.2006"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.23.1.163-177.2003"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-1981(02)00210-X"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-1981(02)00337-2"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.3.651-653.2000"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(02)03067-3"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI27890"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.9.8.1787"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00448-08"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2012.08017.x"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(04)00156-5"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2004.03.004"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.12.7049-7060.2000"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0098149"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/12.4.251"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00647-15"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2012.04.045"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197907193010303"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt221"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200705076"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e02-04-0186"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.15.4035"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.7.3254"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.2217\/FMB.15.47"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-005-1955-9"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1117280109"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2012.00286"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2011.01.015"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4914(02)02280-3"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.1.2.187"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03320490047035"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.3.981-985.2001"},{"key":"e_1_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.6.1364"},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1086\/367933"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1586\/eri.09.67"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1562894"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01130-15"},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkf045"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14472-8"},{"key":"e_1_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2007.05872.x"},{"key":"e_1_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2010.01474.x"},{"key":"e_1_3_3_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/mmy.39.1.1.8-0"},{"key":"e_1_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.2165\/11585270-000000000-00000"},{"key":"e_1_3_3_53_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.2.331"},{"key":"e_1_3_3_54_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.11.2333"},{"key":"e_1_3_3_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2005.01.002"},{"key":"e_1_3_3_56_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000111"},{"key":"e_1_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01973-15"},{"key":"e_1_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.856001"},{"key":"e_1_3_3_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2006.02.061"},{"key":"e_1_3_3_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(97)00692-3"},{"key":"e_1_3_3_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-005-0187-3"},{"key":"e_1_3_3_62_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015572"},{"key":"e_1_3_3_63_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-015-1613-y"},{"key":"e_1_3_3_64_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003832"},{"key":"e_1_3_3_65_1","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00255-08"},{"key":"e_1_3_3_66_1","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00285-06"},{"key":"e_1_3_3_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)32388-9"},{"key":"e_1_3_3_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.10.142"},{"key":"e_1_3_3_69_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2008\/018788-0"},{"key":"e_1_3_3_70_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.033985-0"},{"key":"e_1_3_3_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.605"},{"key":"e_1_3_3_72_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M311165200"},{"key":"e_1_3_3_73_1","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00318-06"},{"key":"e_1_3_3_74_1","doi-asserted-by":"publisher","DOI":"10.1006\/anae.2001.0376"},{"key":"e_1_3_3_75_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0001-37652004000100007"},{"key":"e_1_3_3_76_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2011.00212"},{"key":"e_1_3_3_77_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e05-06-0533"},{"key":"e_1_3_3_78_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.193094"},{"key":"e_1_3_3_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1567-1364.2008.00407.x"},{"key":"e_1_3_3_80_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.108.129411"},{"key":"e_1_3_3_81_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10529-014-1631-1"},{"key":"e_1_3_3_82_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R800003-JLR200"},{"key":"e_1_3_3_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2003.09.007"},{"key":"e_1_3_3_84_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.61.080706.093341"},{"key":"e_1_3_3_85_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0019385"},{"key":"e_1_3_3_86_1","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200500465"},{"key":"e_1_3_3_87_1","doi-asserted-by":"publisher","DOI":"10.1128\/EC.5.3.488-498.2006"},{"key":"e_1_3_3_88_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.12.7860-7868.2005"},{"key":"e_1_3_3_89_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.11.112"},{"key":"e_1_3_3_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12374"},{"key":"e_1_3_3_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2006.08.017"},{"key":"e_1_3_3_92_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.01077"},{"key":"e_1_3_3_93_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.051086-0"},{"key":"e_1_3_3_94_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-015-0588-0"},{"key":"e_1_3_3_95_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078905"},{"key":"e_1_3_3_96_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.6225"},{"key":"e_1_3_3_97_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.48.349"},{"key":"e_1_3_3_98_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.D052001"},{"key":"e_1_3_3_99_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389557515666150709122517"},{"key":"e_1_3_3_100_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI76369"},{"key":"e_1_3_3_101_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00056-15"},{"key":"e_1_3_3_102_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.045989-0"},{"key":"e_1_3_3_103_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01140-09"},{"key":"e_1_3_3_104_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm500338n"},{"key":"e_1_3_3_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2013.11.001"},{"key":"e_1_3_3_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2012.11.026"},{"key":"e_1_3_3_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(00)11094-8"},{"key":"e_1_3_3_108_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.51.837"},{"key":"e_1_3_3_109_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.24.14942"},{"key":"e_1_3_3_110_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.12.2765"},{"key":"e_1_3_3_111_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00633-08"},{"key":"e_1_3_3_112_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.5b00029"},{"key":"e_1_3_3_113_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2009.06628.x"},{"key":"e_1_3_3_114_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2012.02225.x"},{"key":"e_1_3_3_115_1","doi-asserted-by":"publisher","DOI":"10.2323\/jgam.61.108"},{"key":"e_1_3_3_116_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568005043340597"}],"container-title":["Future Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.4155\/fmc-2016-0053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T19:54:05Z","timestamp":1716494045000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.4155\/fmc-2016-0053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":115,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.4155\/fmc-2016-0053"],"URL":"https:\/\/doi.org\/10.4155\/fmc-2016-0053","relation":{},"ISSN":["1756-8919","1756-8927"],"issn-type":[{"value":"1756-8919","type":"print"},{"value":"1756-8927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-02-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-05-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-08-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}