{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:51:43Z","timestamp":1791298303714,"version":"4.1.0"},"reference-count":181,"publisher":"Informa UK Limited","issue":"10","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Medical Research Council","award":["MR\/L007665\/1"],"award-info":[{"award-number":["MR\/L007665\/1"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Future Med. Chem."],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.4155\/fmc-2016-0078","type":"journal-article","created":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T18:32:25Z","timestamp":1466620345000},"page":"1063-1084","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":130,"title":["The Road to Avibactam: The First Clinically Useful Non-\u03b2-Lactam Working Somewhat Like a \u03b2-Lactam"],"prefix":"10.1080","volume":"8","author":[{"given":"David Yuxin","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine I","family":"Abboud","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios S","family":"Markoulides","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Brem","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J","family":"Schofield","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,6,21]]},"reference":[{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70071-4"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2013.86"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0923-2508(91)90084-N"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/cb700182u"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.52.070183.004141"},{"issue":"2","key":"e_1_3_2_8_1","first-page":"107","article-title":"The mechanism of action of penicillin and other \u03b2-lactam antibiotics","volume":"43","author":"Frere JM","year":"1988","unstructured":"Frere JM . The mechanism of action of penicillin and other \u03b2-lactam antibiotics. J. Pharm. Belg.43 (2), 107\u2013115 (1988).","journal-title":"J. Pharm. Belg."},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.33.100179.000553"},{"key":"e_1_3_2_10_1","first-page":"37","article-title":"Penicillin-binding proteins and \u03b2-lactamases: their effects on the use of cephalosporins and other new \u03b2-lactams","volume":"8","author":"Neu HC","year":"1987","unstructured":"Neu HC . Penicillin-binding proteins and \u03b2-lactamases: their effects on the use of cephalosporins and other new \u03b2-lactams. Curr. Clin. Top. Infect. Dis.8, 37\u201361 (1987).","journal-title":"Curr. Clin. Top. Infect. Dis."},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkg050"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2010.09.006"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70056-1"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1875-9114.2012.01157.x"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/a705983c"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2008\/576297"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4MT00066H"},{"issue":"4","key":"e_1_3_2_18_1","first-page":"128","article-title":"The story of penicillin","volume":"8","author":"Fleming A","year":"1955","unstructured":"Fleming A . The story of penicillin. Bull. Georgetown. Univ. Med. Cent.8 (4), 128\u2013132 (1955).","journal-title":"Bull. Georgetown. Univ. Med. Cent."},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201506818"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.13.55"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)30033-5"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4892(01)00079-0"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.2165\/11318430-000000000-00000"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2011.07.026"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi9816249"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)82006-8"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2006.00024.x"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2007.00095.x"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(77)90280-5"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/pauz.19960250107"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.1995.1.103"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2008.12.001"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi500339j"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70139-0"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.46.100192.002333"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1039\/b505964j"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-011-2928-2_1"},{"issue":"5","key":"e_1_3_2_38_1","first-page":"399","article-title":"Evolution of isopenicillin N synthase genes may have involved horizontal gene transfer","volume":"7","author":"Landan G","year":"1990","unstructured":"Landan G , CohenG, AharonowitzY, ShualiY, GraurD, ShiffmanD. Evolution of isopenicillin N synthase genes may have involved horizontal gene transfer. Mol. Biol. Evol.7 (5), 399\u2013406 (1990).","journal-title":"Mol. Biol. Evol."},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1039\/CO9940100417"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-011-2928-2"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389557043487501"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.3987\/S-1987-01-0729"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.3987\/REV-00-SR(I)6"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-894X(97)10123-8"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm000921k"},{"key":"e_1_3_2_46_1","first-page":"165","article-title":"The mechanisms of reactions of \u03b2-lactam antibiotics","volume":"23","author":"Page MI","year":"1987","unstructured":"Page MI . The mechanisms of reactions of \u03b2-lactam antibiotics. Adv. Phys. Org. Chem.23, 165\u2013270 (1987).","journal-title":"Adv. Phys. Org. Chem."},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1039\/c39790000298"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1039\/p29910001213"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1039\/b111627d"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3510335"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01009-09"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00037-09"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1054\/drup.2000.0137"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M505333200"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)61429-8"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi961044g"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b10007"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi035716w"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi702348w"},{"key":"e_1_3_2_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201200006"},{"key":"e_1_3_2_61_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi035985m"},{"key":"e_1_3_2_62_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867322666150311150215"},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/iub.1289"},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja9818001"},{"key":"e_1_3_2_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/359700a0"},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja303579d"},{"key":"e_1_3_2_67_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867023370031"},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi8001055"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.54.4.1133"},{"key":"e_1_3_2_70_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b01374"},{"key":"e_1_3_2_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(65)90093-8"},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M600495200"},{"key":"e_1_3_2_73_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.5b00845"},{"key":"e_1_3_2_74_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja1074739"},{"key":"e_1_3_2_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(71)90393-7"},{"key":"e_1_3_2_76_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.12.5239"},{"key":"e_1_3_2_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2004.10.076"},{"key":"e_1_3_2_78_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi961044g"},{"key":"e_1_3_2_79_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi990098y"},{"issue":"4","key":"e_1_3_2_80_1","first-page":"264","article-title":"A new look at an old drug: artemisinin and qinghaosu","volume":"35","author":"Trevett A","year":"1992","unstructured":"Trevett A , LallooD. A new look at an old drug: artemisinin and qinghaosu. Papua New Guinea Med. J.35 (4), 264\u2013269 (1992).","journal-title":"Papua New Guinea Med. J."},{"key":"e_1_3_2_81_1","doi-asserted-by":"publisher","DOI":"10.1039\/B816679J"},{"key":"e_1_3_2_82_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.44.1"},{"key":"e_1_3_2_83_1","volume-title":"The Chemistry Of Penicillin: Report On A Collaborative Investigation By American And British Chemists Under The Joint Sponsorship Of The Office Of Scientific Research And Development, Washington, DC., And The Medical Research Council, London","year":"1949","unstructured":"The Chemistry Of Penicillin: Report On A Collaborative Investigation By American And British Chemists Under The Joint Sponsorship Of The Office Of Scientific Research And Development, Washington, DC., And The Medical Research Council, London . Princeton University Press, London (1949)."},{"key":"e_1_3_2_84_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm100437u"},{"key":"e_1_3_2_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.2007.21"},{"key":"e_1_3_2_86_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.43.92"},{"key":"e_1_3_2_87_1","unstructured":"Merck & Co: US4428960 (1984)."},{"key":"e_1_3_2_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)84822-4"},{"key":"e_1_3_2_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)84820-0"},{"key":"e_1_3_2_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)80055-7"},{"key":"e_1_3_2_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)84821-2"},{"key":"e_1_3_2_92_1","doi-asserted-by":"publisher","DOI":"10.1039\/P19880002345"},{"key":"e_1_3_2_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/0040-4039(90)80153-D"},{"key":"e_1_3_2_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)99605-9"},{"key":"e_1_3_2_95_1","doi-asserted-by":"publisher","DOI":"10.1039\/C39850000194"},{"key":"e_1_3_2_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)82070-6"},{"key":"e_1_3_2_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)98828-3"},{"key":"e_1_3_2_98_1","doi-asserted-by":"publisher","DOI":"10.1039\/C39830000250"},{"key":"e_1_3_2_99_1","doi-asserted-by":"publisher","DOI":"10.1002\/chin.199203266"},{"key":"e_1_3_2_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)99312-2"},{"key":"e_1_3_2_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)80679-6"},{"key":"e_1_3_2_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)82399-0"},{"key":"e_1_3_2_103_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm000078q"},{"key":"e_1_3_2_104_1","doi-asserted-by":"publisher","DOI":"10.1021\/ol027013x"},{"key":"e_1_3_2_105_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm030810w"},{"key":"e_1_3_2_106_1","doi-asserted-by":"publisher","DOI":"10.1039\/b713899g"},{"key":"e_1_3_2_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)85439-8"},{"key":"e_1_3_2_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)96234-8"},{"key":"e_1_3_2_109_1","doi-asserted-by":"publisher","DOI":"10.1002\/pauz.200790103"},{"key":"e_1_3_2_110_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm500219c"},{"key":"e_1_3_2_111_1","doi-asserted-by":"publisher","DOI":"10.1248\/cpb.38.116"},{"key":"e_1_3_2_112_1","doi-asserted-by":"publisher","DOI":"10.1038\/325179a0"},{"key":"e_1_3_2_113_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.42.84"},{"key":"e_1_3_2_114_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.50.184"},{"key":"e_1_3_2_115_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2070429"},{"key":"e_1_3_2_116_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00604a025"},{"key":"e_1_3_2_117_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules171112478"},{"key":"e_1_3_2_118_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar0200899"},{"key":"e_1_3_2_119_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja056124z"},{"key":"e_1_3_2_120_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01293-06"},{"key":"e_1_3_2_121_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02641-15"},{"key":"e_1_3_2_122_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00930-10"},{"key":"e_1_3_2_123_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja200696y"},{"key":"e_1_3_2_124_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-003-3189-2"},{"key":"e_1_3_2_125_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja056806m"},{"key":"e_1_3_2_126_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm301490d"},{"key":"e_1_3_2_127_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.06099-11"},{"key":"e_1_3_2_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.04.007"},{"key":"e_1_3_2_129_1","unstructured":"Aventis Pharma SA: WO2002010172 (2002)."},{"key":"e_1_3_2_130_1","unstructured":"AstraZeneca: WO2012172368 (2012)."},{"key":"e_1_3_2_131_1","unstructured":"Merck: WO2009091856 (2009)."},{"key":"e_1_3_2_132_1","unstructured":"Merck: WO2012086241 (2012)."},{"key":"e_1_3_2_133_1","doi-asserted-by":"publisher","DOI":"10.1021\/ol202195n"},{"key":"e_1_3_2_134_1","doi-asserted-by":"publisher","DOI":"10.1021\/ol4031606"},{"key":"e_1_3_2_135_1","unstructured":"Novexel: WO2008142285 (2008)."},{"key":"e_1_3_2_136_1","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2012.748653"},{"key":"e_1_3_2_137_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks523"},{"key":"e_1_3_2_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2012.06.003"},{"key":"e_1_3_2_139_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00756-10"},{"key":"e_1_3_2_140_1","unstructured":"Actavis Inc . Prescribing Information: AVYCAZ (ceftazidime-avibactam) for injection for intravenous use. www.accessdata.fda.gov\/drugsatfda_docs\/label\/2015\/206494."},{"key":"e_1_3_2_141_1","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.2010.515588"},{"issue":"2","key":"e_1_3_2_142_1","first-page":"225","article-title":"NXL-103, a combination of flopristin and linopristin, for the potential treatment of bacterial infections including community-acquired pneumonia and MRSA","volume":"11","author":"Politano AD","year":"2010","unstructured":"Politano AD , SawyerRG. NXL-103, a combination of flopristin and linopristin, for the potential treatment of bacterial infections including community-acquired pneumonia and MRSA. Curr. Opin. Investig. Drugs11 (2), 225\u2013236 (2010).","journal-title":"Curr. Opin. Investig. Drugs"},{"key":"e_1_3_2_143_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.5b00944"},{"key":"e_1_3_2_144_1","doi-asserted-by":"publisher","DOI":"10.1021\/ml500284k"},{"key":"e_1_3_2_145_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0136813"},{"key":"e_1_3_2_146_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1205073109"},{"key":"e_1_3_2_147_1","unstructured":"Meiji Seika Pharma Co. Ltd: WO2013180197 (2012)."},{"key":"e_1_3_2_148_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv166"},{"key":"e_1_3_2_149_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.5b00944"},{"key":"e_1_3_2_150_1","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.2013.831071"},{"key":"e_1_3_2_151_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1208337109"},{"key":"e_1_3_2_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.02.065"},{"key":"e_1_3_2_153_1","doi-asserted-by":"publisher","DOI":"10.1038\/nsb0896-688"},{"key":"e_1_3_2_154_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm070643q"},{"key":"e_1_3_2_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2011.02.024"},{"key":"e_1_3_2_156_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.56.838"},{"key":"e_1_3_2_157_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm0703237"},{"key":"e_1_3_2_158_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi972499o"},{"key":"e_1_3_2_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-801922-1.00003-8"},{"key":"e_1_3_2_160_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.485979"},{"key":"e_1_3_2_161_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi500589x"},{"key":"e_1_3_2_162_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00568-10"},{"key":"e_1_3_2_163_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02247-12"},{"key":"e_1_3_2_164_1","doi-asserted-by":"publisher","DOI":"10.1021\/cb500703p"},{"key":"e_1_3_2_165_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkh358"},{"key":"e_1_3_2_166_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6OB00353B"},{"key":"e_1_3_2_167_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi9007963"},{"key":"e_1_3_2_168_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-013-0013-7"},{"key":"e_1_3_2_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2015.02.003"},{"key":"e_1_3_2_170_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn320"},{"key":"e_1_3_2_171_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00817-12"},{"key":"e_1_3_2_172_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq161"},{"key":"e_1_3_2_173_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02123-13"},{"key":"e_1_3_2_174_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00001-07"},{"key":"e_1_3_2_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2013.12.101"},{"key":"e_1_3_2_176_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02704-15"},{"key":"e_1_3_2_177_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv239"},{"key":"e_1_3_2_178_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02184-15"},{"key":"e_1_3_2_179_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05927-11"},{"issue":"10","key":"e_1_3_2_180_1","first-page":"2286","article-title":"Activity of MK-7655 combined with imipenem against Enterobacteriaceae and Pseudomonas aeruginosa","volume":"68","author":"Livermore DM","year":"2013","unstructured":"Livermore DM , WarnerM, MushtaqS. Activity of MK-7655 combined with imipenem against Enterobacteriaceae and Pseudomonas aeruginosa. J. Antimicrob. Chemother.68 (10), 2286\u20132290 (2013).","journal-title":"J. Antimicrob. Chemother."},{"key":"e_1_3_2_181_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.5.1652-1657.2003"},{"key":"e_1_3_2_182_1","doi-asserted-by":"publisher","DOI":"10.1021\/ml5001855"},{"key":"e_1_3_2_183_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt118"}],"container-title":["Future Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.4155\/fmc-2016-0078","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T19:53:54Z","timestamp":1716494034000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.4155\/fmc-2016-0078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":181,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["10.4155\/fmc-2016-0078"],"URL":"https:\/\/doi.org\/10.4155\/fmc-2016-0078","relation":{},"ISSN":["1756-8919","1756-8927"],"issn-type":[{"value":"1756-8919","type":"print"},{"value":"1756-8927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-04-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-05-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-06-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}