{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T10:22:22Z","timestamp":1772792542476,"version":"3.50.1"},"reference-count":149,"publisher":"Informa UK Limited","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharm. Pat. Analyst"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.4155\/ppa.12.59","type":"journal-article","created":{"date-parts":[[2012,11,23]],"date-time":"2012-11-23T14:33:37Z","timestamp":1353681217000},"page":"601-620","source":"Crossref","is-referenced-by-count":5,"title":["New Antibacterial Agents: Patent Applications Published in 2010"],"prefix":"10.1080","volume":"1","author":[{"given":"Suzanne S","family":"Stokes","sequence":"first","affiliation":[{"name":"AstraZeneca Infection Innovative Medicines Unit\r35 Gatehouse Drive\rWaltham\rMA\r02451\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marshall","family":"Morningstar","sequence":"additional","affiliation":[{"name":"AstraZeneca Infection Innovative Medicines Unit\r35 Gatehouse Drive\rWaltham\rMA\r02451\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"Kocis","sequence":"additional","affiliation":[{"name":"AstraZeneca Infection Innovative Medicines Unit\r35 Gatehouse Drive\rWaltham\rMA\r02451\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen C","family":"Verheijen","sequence":"additional","affiliation":[{"name":"AstraZeneca Infection Innovative Medicines Unit\r35 Gatehouse Drive\rWaltham\rMA\r02451\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2012,11,23]]},"reference":[{"key":"e_1_3_3_3_1_1","doi-asserted-by":"publisher","DOI":"10.1086\/524891"},{"key":"e_1_3_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/652237"},{"key":"e_1_3_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/655995"},{"key":"e_1_3_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00030-10"},{"key":"e_1_3_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2011.07.008"},{"key":"e_1_3_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.09.87"},{"key":"e_1_3_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2011.05962.x"},{"key":"e_1_3_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2011.01.014"},{"key":"e_1_3_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01193-07"},{"key":"e_1_3_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1592\/phco.30.3.290"},{"key":"e_1_3_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00860-10"},{"key":"e_1_3_3_3_12_1","unstructured":"Iyengar R KarnatiV WangYet al. The discovery and antibacterial activity of novel 9-OH-6 11-bicyclolides. Presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston MA USA 12\u201315 September 2010."},{"key":"e_1_3_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.4.1458-1462.2006"},{"key":"e_1_3_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2011.06219.x"},{"key":"e_1_3_3_3_15_1","unstructured":"Shanghai Institute of Materia Medica Chinese Academy of Sciences Nanjing Changao Pharmaceutical Science & Technology Co. Ltd: WO2010028542 (2010)."},{"key":"e_1_3_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2010.09.004"},{"key":"e_1_3_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.2010.506189"},{"key":"e_1_3_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-8579(09)70005-6"},{"key":"e_1_3_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1358\/dof.2009.34.1.1324393"},{"key":"e_1_3_3_3_20_1","unstructured":"AG Financial Report Q2 2011."},{"key":"e_1_3_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1109755"},{"key":"e_1_3_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm1015389"},{"key":"e_1_3_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6468(05)44403-3"},{"issue":"8","key":"e_1_3_3_3_24_1","first-page":"804","volume":"10","author":"Black MT","year":"2009","unstructured":"Black MT , ColemanK. New inhibitors of bacterial topoisomerases GyrA\/ParC subunits. Curr. Opin. Invest. Drugs10(8), 804\u2013810 (2009).","journal-title":"Curr. Opin. Invest. Drugs"},{"key":"e_1_3_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00496-08"},{"key":"e_1_3_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09197"},{"key":"e_1_3_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2007.03.004"},{"key":"e_1_3_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm2008826"},{"key":"e_1_3_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2011.09.114"},{"key":"e_1_3_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2011.09.117"},{"key":"e_1_3_3_3_31_1","first-page":"804","volume":"10","author":"Black MT","year":"2009","unstructured":"Black MT , ColemanK. New inhibitors of bacterial topoisomerase GyrA\/ParC subunits. Curr. Opin. Invest. Drugs10, 804\u2013 810 (2009).","journal-title":"Curr. Opin. Invest. Drugs"},{"key":"e_1_3_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr030101q"},{"key":"e_1_3_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00247-08"},{"key":"e_1_3_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568026033452500"},{"key":"e_1_3_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)36592-5"},{"key":"e_1_3_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2010.09.008"},{"key":"e_1_3_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1013092107"},{"key":"e_1_3_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1086\/491709"},{"key":"e_1_3_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/46.4.523"},{"key":"e_1_3_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2010.09.002"},{"key":"e_1_3_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1592\/phco.30.12.1279"},{"key":"e_1_3_3_3_42_1","doi-asserted-by":"crossref","unstructured":"Selva E LanciniG. Rifamycins antibacterial antibiotics and their new applications. In: Analogue-Based Drug Discovery II. Fischer J Ganellin CR (Eds). Wiley-VCH Verlag GmbH & Co. KGaA Weinheim Germany 173\u2013187 (2010).","DOI":"10.1002\/9783527630035.ch7"},{"key":"e_1_3_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm050347i"},{"key":"e_1_3_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm100378b"},{"key":"e_1_3_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00037-09"},{"key":"e_1_3_3_4_2_1","unstructured":"Tri\u03c5s Therapeutics: WO2010138649 (2010)."},{"key":"e_1_3_3_4_3_1","unstructured":"Wockhardt Research Centre: US20100120721 (2010)."},{"key":"e_1_3_3_4_4_1","unstructured":"LegoChem Bioscience: WO2010036000 (2010)."},{"key":"e_1_3_3_4_5_1","unstructured":"Panacea Biotec: WO2010058423 (2010)."},{"key":"e_1_3_3_4_6_1","unstructured":"Shenyang Pharmaceutical University: CN101619061 (2010)."},{"key":"e_1_3_3_4_7_1","unstructured":"Ferrer Internacional: WO2010000703 (2010)."},{"key":"e_1_3_3_4_8_1","unstructured":"Ferrer Internacional: WO2010000704 (2010)."},{"key":"e_1_3_3_4_9_1","unstructured":"Korea Institute of Science and Technology: WO20100063117 (2010)."},{"key":"e_1_3_3_4_10_1","unstructured":"GlaxoSmithKline: WO2010015703 (2010)."},{"key":"e_1_3_3_4_11_1","unstructured":"Enanta Pharmaceuticals Inc.: WO2010096051 (2010)."},{"key":"e_1_3_3_4_12_1","unstructured":"Wockhardt Research Centre: WO2010136971 (2010)."},{"key":"e_1_3_3_4_13_1","unstructured":"Shandong University: CN101899076 (2010)."},{"key":"e_1_3_3_4_14_1","unstructured":"Shandong University: CN101906123 (2010)."},{"key":"e_1_3_3_4_15_1","unstructured":"Wuhan University: CN101863941 (2010)."},{"key":"e_1_3_3_4_16_1","unstructured":"Wuhan University: CN101845069 (2010)."},{"key":"e_1_3_3_4_17_1","unstructured":"Shanghai Institute of Pharmaceutical Industry: CN101830949 (2010)."},{"key":"e_1_3_3_4_18_1","unstructured":"Isis Pharmaceuticals: WO2010030690 (2010)."},{"key":"e_1_3_3_4_19_1","unstructured":"Utah State University: WO2010030808 (2010)."},{"key":"e_1_3_3_4_20_1","unstructured":"University of Manitoba: WO2010004433 (2010)."},{"key":"e_1_3_3_4_21_1","unstructured":"Achaogen Inc.: WO2010132760 (2010)."},{"key":"e_1_3_3_4_22_1","unstructured":"Achaogen Inc.: WO2010132765 (2010)."},{"key":"e_1_3_3_4_23_1","unstructured":"Achaogen Inc.: WO2010132768 (2010)."},{"key":"e_1_3_3_4_24_1","unstructured":"Achaogen Inc.: WO2010132759 (2010)."},{"key":"e_1_3_3_4_25_1","unstructured":"Achaogen Inc. WO2010132757 (2010)."},{"key":"e_1_3_3_4_26_1","unstructured":"Achaogen Inc.: WO2010030704 (2010)."},{"key":"e_1_3_3_4_27_1","unstructured":"Achaogen Inc.: WO2010042850 (2010)."},{"key":"e_1_3_3_4_28_1","unstructured":"Achaogen Inc.: WO2010042851 (2010)."},{"key":"e_1_3_3_4_29_1","unstructured":"Tetraphase Pharmaceuticals: WO2010017470 (2010)."},{"key":"e_1_3_3_4_30_1","unstructured":"Tetraphase Pharmaceuticals: WO2010129055 (2010)."},{"key":"e_1_3_3_4_31_1","unstructured":"Tetraphase Pharmaceuticals: WO2010132670 (2010)."},{"key":"e_1_3_3_4_32_1","unstructured":"Shangong Xuanzhu Pharmaceutical Technology Company: CN101759604 (2010)."},{"key":"e_1_3_3_4_33_1","unstructured":"Glaxo Group Ltd: WO2009061879 (2009)."},{"key":"e_1_3_3_4_34_1","unstructured":"East China Normal University: WO2010145186 (2010)."},{"key":"e_1_3_3_4_35_1","unstructured":"Actelion Pharmaceuticals Ltd: WO2010116337 (2010)."},{"key":"e_1_3_3_4_36_1","unstructured":"Actelion Pharmaceuticals Ltd: WO2010067332 (2010)."},{"key":"e_1_3_3_4_37_1","unstructured":"Actelion Pharmaceuticals Ltd Toyama Chemical Co. Ltd Taisho Pharmaceutical Co.: WO2006137485 (2006)."},{"key":"e_1_3_3_4_38_1","unstructured":"Actelion Pharmaceuticals Ltd: WO2008126034 (2008)."},{"key":"e_1_3_3_4_39_1","unstructured":"Actelion Pharmaceuticals Ltd: WO2008126024 (2008)."},{"key":"e_1_3_3_4_40_1","unstructured":"Actelion Pharmaceuticals Ltd: WO2010041218 (2010)."},{"key":"e_1_3_3_4_41_1","unstructured":"Actelion Pharmaceuticals Ltd: WO2010041219 (2010)."},{"key":"e_1_3_3_4_42_1","unstructured":"Actelion Pharmaceuticals Ltd: WO2010015985 (2010)."},{"key":"e_1_3_3_4_43_1","unstructured":"Actelion Pharmaceuticals Ltd: WO2010041194 (2010)."},{"key":"e_1_3_3_4_44_1","unstructured":"Actelion Pharmaceuticals Ltd: WO2009104147 (2009)."},{"key":"e_1_3_3_4_45_1","unstructured":"Glaxo Group Ltd: WO2010081874 (2010)."},{"key":"e_1_3_3_4_46_1","unstructured":"Glaxo Group Ltd: WO2010046388 (2010)."},{"key":"e_1_3_3_4_47_1","unstructured":"Glaxo Group Ltd: WO2010045987 (2010)."},{"key":"e_1_3_3_4_48_1","unstructured":"Glaxo Group Ltd: WO2009090222 (2010)."},{"key":"e_1_3_3_4_49_1","unstructured":"Glaxo Group Ltd: WO2010043714 (2010)."},{"key":"e_1_3_3_4_50_1","doi-asserted-by":"crossref","unstructured":"AstraZeneca AB: WO2010055348 (2010).","DOI":"10.3833\/pdr.v2010i5.1345"},{"key":"e_1_3_3_4_51_1","unstructured":"Janssen Pharmaceutica N.V.: WO2010093341 (2010)."},{"key":"e_1_3_3_4_52_1","unstructured":"Janssen Pharmaceutica N.V.: WO200503310 (2005)."},{"key":"e_1_3_3_4_53_1","unstructured":"Janssen Pharmaceutica N.V.: WO2010056633(2010)."},{"key":"e_1_3_3_4_54_1","unstructured":"Vetoquinol SA: WO2010004394 (2010)."},{"key":"e_1_3_3_4_55_1","unstructured":"Vetoquinol SA: WO2009106967 (2009)."},{"key":"e_1_3_3_4_56_1","unstructured":"Achillion Pharmaceuticals Inc.: WO2010115184 (2010)."},{"key":"e_1_3_3_4_57_1","unstructured":"Achillion Pharmaceuticals Inc.: US20090012071 (2009)."},{"key":"e_1_3_3_4_58_1","unstructured":"Dainippon Pharmaceutical Co Ltd: JP03223289 (2010)."},{"key":"e_1_3_3_4_59_1","unstructured":"Pfizer Inc.: WO2004031195 (2004)."},{"key":"e_1_3_3_4_60_1","doi-asserted-by":"crossref","unstructured":"AstraZeneca AB: WO2010043893 (2010).","DOI":"10.3833\/pdr.v2010i5.1345"},{"key":"e_1_3_3_4_61_1","unstructured":"Ranbaxy Laboratories Ltd: WO2010013222 (2010)."},{"key":"e_1_3_3_4_62_1","doi-asserted-by":"crossref","unstructured":"AstraZeneca AB: WO2010067123 (2010).","DOI":"10.3833\/pdr.v2010i5.1345"},{"key":"e_1_3_3_4_63_1","doi-asserted-by":"crossref","unstructured":"AstraZeneca AB: WO2010067125 (2010).","DOI":"10.3833\/pdr.v2010i5.1345"},{"key":"e_1_3_3_4_64_1","doi-asserted-by":"crossref","unstructured":"AstraZeneca AB: WO2010142978 (2010).","DOI":"10.3833\/pdr.v2010i5.1345"},{"key":"e_1_3_3_4_65_1","doi-asserted-by":"crossref","unstructured":"AstraZeneca AB: WO2010136817 (2010).","DOI":"10.3833\/pdr.v2010i5.1345"},{"key":"e_1_3_3_4_66_1","doi-asserted-by":"crossref","unstructured":"AstraZeneca AB: WO2010038081 (2010).","DOI":"10.3833\/pdr.v2010i5.1345"},{"key":"e_1_3_3_4_67_1","unstructured":"Schering Corporation: WO2010017060 (2010)."},{"key":"e_1_3_3_4_68_1","unstructured":"Novartis AG: WO2010031750 (2010)."},{"key":"e_1_3_3_4_69_1","unstructured":"Pfizer Inc.: WO2010032147 (2010)."},{"key":"e_1_3_3_4_70_1","unstructured":"Taisho Pharmaceutical Co. Ltd Toyama Chemical Co. Ltd: WO2010024356 (2010)."},{"key":"e_1_3_3_4_71_1","doi-asserted-by":"crossref","unstructured":"AstraZeneca AB: WO2010100475 (2010).","DOI":"10.3833\/pdr.v2010i5.1345"},{"key":"e_1_3_3_4_72_1","unstructured":"Yokohama City University: JP2010047520 (2010)."},{"key":"e_1_3_3_4_73_1","unstructured":"Parnell Laboratories (Aust) Pty. Ltd: WO2010028458 (2010)."},{"key":"e_1_3_3_4_74_1","unstructured":"Tianjin Pharmaceutical Group Technology Development Co. Ltd: CN101671351(2010)."},{"key":"e_1_3_3_4_75_1","unstructured":"KBP Biosciences Ltd: CN101712689 (2010)."},{"key":"e_1_3_3_4_76_1","unstructured":"KBP Biosciences Ltd: CN101759710 (2010)."},{"key":"e_1_3_3_4_77_1","unstructured":"KBP Biosciences Ltd: CN101798315 (2010)."},{"key":"e_1_3_3_4_78_1","unstructured":"KBP Biosciences Ltd: CN101899059 (2010)."},{"key":"e_1_3_3_4_79_1","unstructured":"KBP Biosciences Ltd: WO2010083725 (2010)."},{"key":"e_1_3_3_4_80_1","unstructured":"Shionogi and Co. Ltd: WO2010050468 (2010)."},{"key":"e_1_3_3_4_81_1","unstructured":"Forest Laboratories Holdings Ltd: WO2010096798 (2010)."},{"key":"e_1_3_3_4_82_1","unstructured":"KBP Biosciences Ltd: CN101648952 (2010)."},{"key":"e_1_3_3_4_83_1","unstructured":"Amplyx Pharmaceuticals Inc. WO2010065110 (2010)."},{"key":"e_1_3_3_4_84_1","unstructured":"Achaogen Inc.: WO2010030810 (2010)."},{"key":"e_1_3_3_4_85_1","unstructured":"Achaogen Inc.: WO2010030811 (2010)."},{"key":"e_1_3_3_4_86_1","unstructured":"Achaogen Inc.: WO2010123997 (2010)."},{"key":"e_1_3_3_4_87_1","unstructured":"Pfizer Inc.: WO2010070523 (2010)."},{"key":"e_1_3_3_4_88_1","unstructured":"Lead Therapeutics Inc.: US20100216699 (2010)."},{"key":"e_1_3_3_4_89_1","unstructured":"Lead Therapeutics Inc.: WO2009085562 (2010)."},{"key":"e_1_3_3_4_90_1","unstructured":"Lead Therapeutics Inc.: WO2010048340 (2010)."},{"key":"e_1_3_3_4_91_1","unstructured":"Lead Therapeutics Inc.: WO2010065174 (2010)."},{"key":"e_1_3_3_4_92_1","unstructured":"Cubist Pharmaceuticals Inc.: WO2010075215 (2010)."},{"key":"e_1_3_3_4_93_1","unstructured":"BioSource Pharm Inc.: WO2010075416 (2010)."},{"key":"e_1_3_3_4_94_1","unstructured":"Monash University: WO2010130007 (2010)."},{"key":"e_1_3_3_4_95_1","unstructured":"Janssen Pharmaceutica: WO2010068383 (2010)."},{"key":"e_1_3_3_4_96_1","unstructured":"Janssen Pharmaceutica: US20100029669 (2010)."},{"key":"e_1_3_3_4_97_1","unstructured":"University of Colorado: WO2010141760 (2010)."},{"key":"e_1_3_3_4_98_1","unstructured":"Southern Methodist University: US20100009954 (2010)."},{"key":"e_1_3_3_4_99_1","unstructured":"Sopharmia Inc.: WO2010118361(2010)."},{"key":"e_1_3_3_4_100_1","unstructured":"Sopharmia Inc.: WO2009049086 (2010)."},{"key":"e_1_3_3_4_101_1","unstructured":"Novexel: WO2010038115 (2010)."},{"key":"e_1_3_3_4_102_1","unstructured":"Novexel: WO2010041108 (2010)."},{"key":"e_1_3_3_4_103_1","unstructured":"Novexel: WO2010041112 (2010)."},{"key":"e_1_3_3_4_104_1","unstructured":"Novartis AG: WO2010130708 (2010)."},{"key":"e_1_3_3_4_105_1","unstructured":"Mpex Pharmaceuticals Inc.: US20100152098 (2010)."}],"container-title":["Pharmaceutical Patent Analyst"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.4155\/ppa.12.59","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T00:17:50Z","timestamp":1715991470000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.4155\/ppa.12.59"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":149,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.4155\/ppa.12.59"],"URL":"https:\/\/doi.org\/10.4155\/ppa.12.59","relation":{},"ISSN":["2046-8954","2046-8962"],"issn-type":[{"value":"2046-8954","type":"print"},{"value":"2046-8962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}