{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T08:53:37Z","timestamp":1780044817380,"version":"3.53.1"},"reference-count":79,"publisher":"Informa UK Limited","issue":"4","funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["Grant #456403\/2014-0"],"award-info":[{"award-number":["Grant #456403\/2014-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["#2017\/07314-1"],"award-info":[{"award-number":["#2017\/07314-1"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Ther. Deliv."],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.4155\/tde-2022-0068","type":"journal-article","created":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T07:31:54Z","timestamp":1688455914000},"page":"295-309","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":10,"title":["Characterization and Antifungal Activity of Chlorhexidine:\u03b2-cyclodextrin Inclusion Complexes"],"prefix":"10.1080","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6978-4913","authenticated-orcid":false,"given":"Amanda Cristina","family":"Schoeffel","sequence":"first","affiliation":[{"name":"Department of Dentistry State University of Ponta Grossa (UEPG) Ponta Grossa\r          PR\r          84030-900\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4200-9973","authenticated-orcid":false,"given":"Francine Sumie","family":"Morikava","sequence":"additional","affiliation":[{"name":"Department of Dentistry State University of Ponta Grossa (UEPG) Ponta Grossa\r          PR\r          84030-900\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6805-1603","authenticated-orcid":false,"given":"Amanda Migliorini","family":"Urban","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences State University of Ponta Grossa (UEPG) Ponta Grossa\r          PR\r          84030-900\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8327-6285","authenticated-orcid":false,"given":"Andressa","family":"Novatski","sequence":"additional","affiliation":[{"name":"Department of Physics State University of Ponta Grossa (UEPG) Ponta Grossa\r          PR\r          84030-900\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0777-5012","authenticated-orcid":false,"given":"Gustavo Sim\u00e3o","family":"Moraes","sequence":"additional","affiliation":[{"name":"Department of Dentistry State University of Ponta Grossa (UEPG) Ponta Grossa\r          PR\r          84030-900\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2531-2567","authenticated-orcid":false,"given":"Graciette","family":"Matioli","sequence":"additional","affiliation":[{"name":"Department of Pharmacy State University of Maring\u00e1 (UEM) Maring\u00e1\r          PR\r          87020-900\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4285-6646","authenticated-orcid":false,"given":"Priscileila Colerato","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences State University of Ponta Grossa (UEPG) Ponta Grossa\r          PR\r          84030-900\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7086-2667","authenticated-orcid":false,"given":"Karin Hermana","family":"Neppelenbroek","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics & Periodontics Bauru School of Dentistry University of S\u00e3o Paulo (USP)\r          Bauru\r          17012-901\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9934-4027","authenticated-orcid":false,"given":"Paulo Vitor","family":"Farago","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences State University of Ponta Grossa (UEPG) Ponta Grossa\r          PR\r          84030-900\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3320-8783","authenticated-orcid":false,"given":"Vanessa Migliorini","family":"Urban","sequence":"additional","affiliation":[{"name":"Department of Dentistry State University of Ponta Grossa (UEPG) Ponta Grossa\r          PR\r          84030-900\r          Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,7,4]]},"reference":[{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.18869\/acadpub.cmm.2.2.1"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof3040057"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/10837450.2014.999783"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.16-0295"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03933.x"},{"issue":"1","key":"e_1_3_4_8_1","first-page":"17","article-title":"Treatment of denture-induced stomatitis: a review","volume":"2","author":"Lombardi T","year":"1993","unstructured":"Lombardi T , Budtz-JorgensenE. Treatment of denture-induced stomatitis: a review. Eur. J. Prosthodont. Restor. Dent.2(1), 17\u201322 (1993).","journal-title":"Eur. J. Prosthodont. Restor. Dent."},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2008.01874.x"},{"issue":"5","key":"e_1_3_4_10_1","first-page":"ZC97","article-title":"Efficacy of neem extract and three antimicrobial agents incorporated into tissue conditioner in inhibiting the growth of C. albicans and S. mutans","volume":"11","author":"Barua DR","year":"2017","unstructured":"Barua DR , BasavannaJM, VargheseRK. Efficacy of neem extract and three antimicrobial agents incorporated into tissue conditioner in inhibiting the growth of C. albicans and S. mutans. J. Clin. Diagn. Res.11(5), ZC97\u2013ZC101 (2017).","journal-title":"J. Clin. Diagn. Res."},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2001.tb00216.x"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2022.104297"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2019.08.028"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.11607\/ijp.5653"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12207"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.4155\/tde-2021-0074"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2007.08.025"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/62634"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.01522"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2012.00639.x"},{"issue":"2","key":"e_1_3_4_21_1","first-page":"50","article-title":"Colonization and deterioration of soft denture lining materials in vivo","volume":"16","author":"Taylor RL","year":"2008","unstructured":"Taylor RL , BuladK, VerranJ, McCordJF. Colonization and deterioration of soft denture lining materials in vivo. Eur. J. Prosthodont. Restor. Dent.16(2), 50\u201355 (2008).","journal-title":"Eur. J. Prosthodont. Restor. Dent."},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(92)90206-P"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpor.2018.03.002"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.59566\/IJBS.2016.12130"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2015.09.029"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.4012\/dmj.2014-269"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-775720160092"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1590\/0103-6440201701266"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/jopr.12660"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2018.02.005"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-7757-2020-0639"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2010.01968.x"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-849X.2011.00774.x"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.10.002"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.01.021"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2012.02.016"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S18297"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0123709"},{"key":"e_1_3_4_39_1","first-page":"26","article-title":"Physicochemical characteristics and pharmaceutical uses of cyclodextrin derivates, part I","volume":"6","author":"Duch\u00eane D","year":"1990","unstructured":"Duch\u00eane D , WouessidjeweD. Physicochemical characteristics and pharmaceutical uses of cyclodextrin derivates, part I. Pharm. Technol.6, 26\u201334 (1990).","journal-title":"Pharm. Technol."},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2013.12.067"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389450121666200615150039"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr970025p"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.3109\/10717544.2013.879679"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26020505"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2021.102283"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.4103\/0975-7406.94163"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15030914"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2021-0274"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2021.121163"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2015.06.032"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-016-0478-2"},{"key":"e_1_3_4_52_1","first-page":"117","article-title":"Phase-solubility techniques","volume":"4","author":"Higuchi T","year":"1965","unstructured":"Higuchi T , ConnorsKA. Phase-solubility techniques. Adv. Anal. Chem. Instr.4, 117\u2013122 (1965).","journal-title":"Adv. Anal. Chem. Instr."},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2010.05.001"},{"issue":"10","key":"e_1_3_4_54_1","first-page":"1533","article-title":"Characterization, antifungal evaluation against Candida spp. strains, and application of nystatin:\u03b2-cyclodextrin inclusion complexes","volume":"20","author":"Urban AM","year":"2022","unstructured":"Urban AM , MorikavaFS, SchoeffelACet al. Characterization, antifungal evaluation against Candida spp. strains, and application of nystatin:\u03b2-cyclodextrin inclusion complexes. Curr. Drug Deliv.20(10), 1533\u20131546 (2022).","journal-title":"Curr. Drug Deliv."},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.30638\/eemj.2015.031"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2007.01935.x"},{"issue":"4","key":"e_1_3_4_57_1","first-page":"163","article-title":"Characteristics of biofilm formation by Candida albicans","volume":"18","author":"Ramage G","year":"2001","unstructured":"Ramage G , VandewalleK, WickesBL, Lopez-RibotJL. Characteristics of biofilm formation by Candida albicans. Rev. Iberoam. Micol.18(4), 163\u2013170 (2001).","journal-title":"Rev. Iberoam. Micol."},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-64402008000400014"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.34119\/bjhrv4n5-234"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345010800031101"},{"key":"e_1_3_4_61_1","unstructured":"National Committee for Clinical Laboratory Standards . M27- A2: reference method for broth dilution antifungal susceptibility testing of yeasts; Approved Standard \u2013Second Edition.. National Committee for Clinical Laboratory Standards PA USA (2002). www.researchgate.net\/file.PostFileLoader.html?id=55b324fe5e9d97d2638b45b8&assetKey=AS%3A273819233652736%401442295000257"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.1.506-508.2003"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.001436"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-012-9853-9"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2010.09.027"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2007.05.012"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1248\/cpb.37.211"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.05.042"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2015.01.058"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.21453"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1021\/ma001868c"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1025494500283"},{"key":"e_1_3_4_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2004.11.013"},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1208\/pt0803060"},{"key":"e_1_3_4_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2007.05.002"},{"key":"e_1_3_4_76_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-009-9249-7"},{"key":"e_1_3_4_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2019.05.034"},{"key":"e_1_3_4_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2014.07.004"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb-2019-0107"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.12.028"},{"key":"e_1_3_4_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2012.07.009"}],"container-title":["Therapeutic Delivery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.4155\/tde-2022-0068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T20:33:43Z","timestamp":1715978023000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.4155\/tde-2022-0068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":79,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.4155\/tde-2022-0068"],"URL":"https:\/\/doi.org\/10.4155\/tde-2022-0068","relation":{},"ISSN":["2041-5990","2041-6008"],"issn-type":[{"value":"2041-5990","type":"print"},{"value":"2041-6008","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=itde20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=itde20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2022-12-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}