{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T06:35:51Z","timestamp":1762497351819,"version":"build-2065373602"},"reference-count":10,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T00:00:00Z","timestamp":1602460800000},"content-version":"vor","delay-in-days":591,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008457","name":"University of Virginia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008457","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aaceclinicalcasereports.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["AACE Clinical Case Reports"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.4158\/accr-2018-0288","type":"journal-article","created":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T14:15:38Z","timestamp":1541081738000},"page":"e164-e167","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Reduction in Thymoma Size After Pituitary Surgery for Growth Hormone\u2013Secreting Tumor"],"prefix":"10.1016","volume":"5","author":[{"given":"Hema","family":"Padmanabhan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.4158\/ACCR-2018-0288_bb0010","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1210\/edrv-4-3-271","article-title":"Pathophysiology of acromegaly","volume":"4","author":"Melmed","year":"1983","journal-title":"Endocr Rev"},{"key":"10.4158\/ACCR-2018-0288_bb0015","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1172\/JCI109658","article-title":"Partial purification and characterization of a peptide with growth hormone-releasing activity from extrapituitary tumors in patients with acromegaly","volume":"65","author":"Frohman","year":"1980","journal-title":"J Clin Invest"},{"key":"10.4158\/ACCR-2018-0288_bb0020","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1172\/JCI110708","article-title":"Somatotroph hyperplasia. Successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor","volume":"70","author":"Thorner","year":"1982","journal-title":"J Clin Invest"},{"key":"10.4158\/ACCR-2018-0288_bb0025","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1126\/science.6812220","article-title":"Growth hormone-releasing factor from a human pancreatic tumor that caused acromegaly","volume":"218","author":"Guillemin","year":"1982","journal-title":"Science"},{"key":"10.4158\/ACCR-2018-0288_bb0030","doi-asserted-by":"crossref","first-page":"425","DOI":"10.2165\/00003495-199447030-00004","article-title":"Acromegaly. Recognition and treatment","volume":"47","author":"Jaffe","year":"1994","journal-title":"Drugs"},{"key":"10.4158\/ACCR-2018-0288_bb0035","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1210\/jcem-67-2-395","article-title":"Medical management of acromegaly due to ectopic production of growth hormone-releasing hormone by a carcinoid tumor","volume":"67","author":"Melmed","year":"1988","journal-title":"J Clin Endocrinol Metab"},{"issue":"suppl 2","key":"10.4158\/ACCR-2018-0288_bb0040","first-page":"63","article-title":"Functional imaging of thymic disorders","volume":"31","author":"Lastoria","year":"1999","journal-title":"Ann Med"},{"key":"10.4158\/ACCR-2018-0288_bb0045","first-page":"2663","article-title":"Growth hormone synthesized and secreted by human thymocytes acts via insulin-like growth factor 1 as an autocrine and paracrine growth factor","volume":"81","author":"Sabharwal","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/ACCR-2018-0288_bb0050","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1046\/j.1365-3083.2002.01077.x","article-title":"The thymus gland: a target organ for growth hormone","volume":"55","author":"Savino","year":"2002","journal-title":"Scand J immunol"},{"key":"10.4158\/ACCR-2018-0288_bb0055","first-page":"1135","article-title":"The in vitro proliferation of thymus epithelial cells stimulated with growth hormone and insulin-like growth factor-1","volume":"40","author":"Tsuji","year":"1994","journal-title":"Cell Mol Bio"}],"container-title":["AACE Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2376060520305125?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2376060520305125?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T06:30:58Z","timestamp":1762497058000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2376060520305125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S2376060520305125"],"URL":"https:\/\/doi.org\/10.4158\/accr-2018-0288","relation":{},"ISSN":["2376-0605"],"issn-type":[{"type":"print","value":"2376-0605"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reduction in Thymoma Size After Pituitary Surgery for Growth Hormone\u2013Secreting Tumor","name":"articletitle","label":"Article Title"},{"value":"AACE Clinical Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.4158\/ACCR-2018-0288","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2019 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}