{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T21:11:57Z","timestamp":1776287517732,"version":"3.50.1"},"reference-count":38,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["aacejournalendocrinepractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrine Practice"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.4158\/ep.12.1.48","type":"journal-article","created":{"date-parts":[[2013,4,5]],"date-time":"2013-04-05T21:37:11Z","timestamp":1365197831000},"page":"48-53","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":83,"title":["Bisphosphonate-Induced Hypocalcemia: Report of 3 Cases and Review of Literature"],"prefix":"10.1016","volume":"12","author":[{"given":"Naim M.","family":"Maalouf","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard J.","family":"Heller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clarita V.","family":"Odvina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khashayar","family":"Sakhaee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.4158\/EP.12.1.48_bb0005","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0889-8529(02)00079-8","article-title":"Bisphosphonates","volume":"32","author":"McClung","year":"2003","journal-title":"Endocrinol Metab Clin North Am."},{"key":"10.4158\/EP.12.1.48_bb0010","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1001\/archinte.164.14.1525","article-title":"National trends in osteoporosis visits and osteoporosis treatment, 1988-2003","volume":"164","author":"Stafford","year":"2004","journal-title":"Arch Intern Med."},{"key":"10.4158\/EP.12.1.48_bb0015","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1016\/S0149-2918(03)80327-2","article-title":"Zoledronic acid: a new parenteral bisphosphonate","volume":"25","author":"Li","year":"2003","journal-title":"Clin Ther."},{"key":"10.4158\/EP.12.1.48_bb0020","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1210\/edrv.19.1.0325","article-title":"Bisphosphonates: mechanisms of action","volume":"19","author":"Fleisch","year":"1998","journal-title":"Endocr Rev."},{"key":"10.4158\/EP.12.1.48_bb0025","first-page":"69","article-title":"Effects of decreasing serum calcium on circulating parathyroid hormone and vitamin D metabolites in normocalcaemic and hypercalcaemic patients treated with APD","volume":"1","author":"Papapoulos","year":"1986","journal-title":"Bone Miner."},{"key":"10.4158\/EP.12.1.48_bb0030","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0002-9343(99)80134-X","article-title":"Alendronate treatment of the postmenopausal osteoporotic woman: effect of multiple dosages on bone mass and bone remodeling","volume":"99","author":"Chesnut","year":"1995","journal-title":"Am J Med."},{"key":"10.4158\/EP.12.1.48_bb0035","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1177\/0091270002239824","article-title":"The pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with varying degrees of renal function","volume":"43","author":"Skerjanec","year":"2003","journal-title":"J Clin Pharmacol."},{"key":"10.4158\/EP.12.1.48_bb0040","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1046\/j.1365-2125.2000.00135.x","article-title":"Effect of renal function on risedronate pharmacokinetics after a single oral dose","volume":"49","author":"Mitchell","year":"2000","journal-title":"Br J Clin Pharmacol."},{"key":"10.4158\/EP.12.1.48_bb0045","first-page":"1399","article-title":"The effect of short term treatment with alendronate on vertebral density and biochemical markers of bone remodeling in early post-menopausal women","volume":"76","author":"Harris","year":"1993","journal-title":"J Clin Endocrinol Metab."},{"key":"10.4158\/EP.12.1.48_bb0050","first-page":"396","article-title":"Risedronate increases bone mass in an early postmenopausal population: two years of treatment plus one year of follow-up","volume":"83","author":"Mortensen","year":"1998","journal-title":"J Clin Endocrinol Metab."},{"key":"10.4158\/EP.12.1.48_bb0055","unstructured":"Zoledronic acid product label [online]. Available at: http:\/\/www.fda.gov\/medwatch\/SAFETY\/2004\/Zometa_PI.pdf. Accessed for verification August 16, 2005."},{"key":"10.4158\/EP.12.1.48_bb0060","unstructured":"Pamidronate product label [online]. Available at: http:\/\/www.fda.gov\/medwatch\/SAFETY\/2004\/mar_PI\/Aredia_PI.pdf. Accessed for verification August 16, 2005."},{"key":"10.4158\/EP.12.1.48_bb0065","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0140-6736(87)90255-8","article-title":"Symptomatic hypocalcaemia after treatment with high-dose aminohydroxypropylidene diphosphonate [letter]","volume":"1","author":"Jodrell","year":"1987","journal-title":"Lancet."},{"key":"10.4158\/EP.12.1.48_bb0070","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1136\/bmj.328.7435.335","article-title":"Severe hypocalcaemia after being given intravenous bisphosphonate","volume":"328","author":"Peter","year":"2004","journal-title":"BMJ."},{"key":"10.4158\/EP.12.1.48_bb0075","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1200\/JCO.2004.99.013","article-title":"Prolonged hypocalcemia after treatment with zoledronic acid in a patient with prostate cancer and vitamin D deficiency [letter]","volume":"22","author":"Breen","year":"2004","journal-title":"J Clin Oncol."},{"key":"10.4158\/EP.12.1.48_bb0080","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1056\/NEJM200304103481521","article-title":"Severe hypocalcemia after intravenous bisphosphonate therapy in occult vitamin D deficiency [letter]","volume":"348","author":"Rosen","year":"2003","journal-title":"N Engl J Med."},{"key":"10.4158\/EP.12.1.48_bb0085","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1177\/014107680209501212","article-title":"Seizures after alendronate","volume":"95","author":"MacIsaac","year":"2002","journal-title":"J R Soc Med."},{"key":"10.4158\/EP.12.1.48_bb0090","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0885-3924(02)00644-9","article-title":"Hypocalcemia following pamidronate administration for bone metastases of solid tumor: three clinical case reports","volume":"25","author":"Champallou","year":"2003","journal-title":"J Pain Symptom Manage."},{"key":"10.4158\/EP.12.1.48_bb0095","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1345\/aph.1D357","article-title":"Hypocalcemia and azotemia associated with zoledronic acid and interferon alfa","volume":"38","author":"Tanvetyanon","year":"2004","journal-title":"Ann Pharmacother."},{"key":"10.4158\/EP.12.1.48_bb0100","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/S0885-3924(98)80015-8","article-title":"Symptomatic hypocalcemia with oral clodronate","volume":"15","author":"Johnson","year":"1998","journal-title":"J Pain Symptom Manage."},{"key":"10.4158\/EP.12.1.48_bb0105","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1001\/jama.281.16.1505","article-title":"Occult vitamin D deficiency in postmenopausal US women with acute hip fracture","volume":"281","author":"LeBoff","year":"1999","journal-title":"JAMA."},{"key":"10.4158\/EP.12.1.48_bb0110","doi-asserted-by":"crossref","first-page":"292","DOI":"10.4158\/EP.10.3.292","article-title":"Prevalence of vitamin D deficiency in patients attending an outpatient cancer care clinic in Boston [letter]","volume":"10","author":"Tangpricha","year":"2004","journal-title":"Endocr Pract."},{"key":"10.4158\/EP.12.1.48_bb0115","first-page":"175","article-title":"Safety of pamidronate in patients with renal failure and hypercalcemia","volume":"45","author":"Machado","year":"1996","journal-title":"Clin Nephrol."},{"key":"10.4158\/EP.12.1.48_bb0120","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1111\/j.1532-5415.1990.tb05704.x","article-title":"The effect of hypoparathyroidism on the aging skeleton","volume":"38","author":"Shukla","year":"1990","journal-title":"J Am Geriatr Soc."},{"key":"10.4158\/EP.12.1.48_bb0125","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/00000441-199508000-00003","article-title":"Hypoparathyroidism counteracts risk factors for osteoporosis","volume":"310","author":"Touliatos","year":"1995","journal-title":"Am J Med Sci."},{"key":"10.4158\/EP.12.1.48_bb0130","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0936-6555(98)80045-9","article-title":"Severe prolonged hypocalcaemia following pamidronate for malignant hypercalcaemia","volume":"10","author":"Sims","year":"1998","journal-title":"Clin Oncol (R Coll Radiol)."},{"key":"10.4158\/EP.12.1.48_bb0135","doi-asserted-by":"crossref","first-page":"396","DOI":"10.2169\/internalmedicine.37.396","article-title":"Symptomatic hypocalcemia in a patient with latent hypoparathyroidism and breast carcinoma with bone metastasis following administration of pamidronate","volume":"37","author":"Comlekci","year":"1998","journal-title":"Intern Med."},{"key":"10.4158\/EP.12.1.48_bb0140","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1385\/ENDO:14:2:159","article-title":"Prolonged, symptomatic hypocalcemia with pamidronate administration and subclinical hypoparathyroidism","volume":"14","author":"Mishra","year":"2001","journal-title":"Endocrine."},{"key":"10.4158\/EP.12.1.48_bb0145","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1359\/jbmr.2001.16.9.1719","article-title":"Bisphosphonate therapy for Paget\u2019s disease in a patient with hypoparathyroidism: profound hypocalcemia, rapid response, and prolonged remission","volume":"16","author":"Stuckey","year":"2001","journal-title":"J Bone Miner Res."},{"issue":"4 Pt 1","key":"10.4158\/EP.12.1.48_bb0150","doi-asserted-by":"crossref","first-page":"329","DOI":"10.7326\/0003-4819-130-4-199902160-00008","article-title":"Hypocalcemia associated with alendronate [letter]","volume":"130","author":"Schussheim","year":"1999","journal-title":"Ann Intern Med."},{"key":"10.4158\/EP.12.1.48_bb0155","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1136\/pmj.76.897.417","article-title":"Hypoparathyroidism unmasked by alendronate","volume":"76","author":"Kashyap","year":"2000","journal-title":"Postgrad Med J."},{"key":"10.4158\/EP.12.1.48_bb0160","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1136\/bmj.302.6771.295","article-title":"Severe hypocalcaemia [corrected] after treatment with diphosphonate and aminoglycoside [letter]","volume":"302","author":"Pedersen-Bjergaard","year":"1991","journal-title":"BMJ."},{"key":"10.4158\/EP.12.1.48_bb0165","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1177\/082585979601200109","article-title":"Symptomatic hypocalcemia after intravenous pamidronate","volume":"12","author":"McIntyre","year":"1996","journal-title":"J Palliat Care."},{"key":"10.4158\/EP.12.1.48_bb0170","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1445-5994.1999.tb01601.x","article-title":"Symptomatic hypocalcaemia following intravenous pamidronate in cancer patients [letter]","volume":"29","author":"Chong","year":"1999","journal-title":"Aust N Z J Med."},{"key":"10.4158\/EP.12.1.48_bb0175","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1093\/oxfordjournals.annonc.a058530","article-title":"Severe hypocalcaemia after treatment with oral clodronate and aminoglycoside [letter]","volume":"4","author":"Mayordomo","year":"1993","journal-title":"Ann Oncol."},{"key":"10.4158\/EP.12.1.48_bb0180","unstructured":"Alendronate product label [online]. Available at: http:\/\/www.fda.gov\/medwatch\/SAFETY\/2003\/03MAR_PI\/Fosamax_PI.pdf. Accessed for verification August 16, 2005."},{"key":"10.4158\/EP.12.1.48_bb0185","unstructured":"Risedronate product label [online]. Available at: http:\/\/www.fda.gov\/medwatch\/SAFETY\/2004\/feb_PI\/Actonel_PI.pdf. Accessed for verification August 16, 2005."},{"key":"10.4158\/EP.12.1.48_bb0190","first-page":"1439","article-title":"Hypocalcaemia after intravenous bisphosphonate: read the product information first [letter]","volume":"328","author":"Breay","year":"2004","journal-title":"BMJ."}],"container-title":["Endocrine Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X20406950?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X20406950?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/aace.metapress.com\/index\/BT4YRL6E09R42M6X.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:46:51Z","timestamp":1761515211000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1530891X20406950"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S1530891X20406950"],"URL":"https:\/\/doi.org\/10.4158\/ep.12.1.48","relation":{},"ISSN":["1530-891X"],"issn-type":[{"value":"1530-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bisphosphonate-Induced Hypocalcemia: Report of 3 Cases and Review of Literature","name":"articletitle","label":"Article Title"},{"value":"Endocrine Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.4158\/EP.12.1.48","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}