{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:25:48Z","timestamp":1792135548167,"version":"4.4.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["aacejournalendocrinepractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrine Practice"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.4158\/ep12207.or","type":"journal-article","created":{"date-parts":[[2013,1,21]],"date-time":"2013-01-21T21:03:25Z","timestamp":1358802205000},"page":"219-225","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Primary Hyperparathyroidism is Associated With subclinical Peripheral Neural Alterations"],"prefix":"10.1016","volume":"19","author":[{"given":"Erik Trov\u00e3o","family":"Diniz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Bandeira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ot\u00e1vio Gomes","family":"Lins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9rica Nogueira","family":"Bezerra Cavalcanti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiago Matos","family":"de Arruda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre Medeiros","family":"Sampaio Janu\u00e1rio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaisa Trov\u00e3o","family":"Diniz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thyciara Fontenele","family":"Marques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hildo","family":"Azevedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.4158\/EP12207.OR_bb0010","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1056\/NEJMcp032200","article-title":"Clinical practice. Asymptomatic primary hyperparathyroidism.","volume":"350","author":"Bilezikian","year":"2004","journal-title":"N Engl J Med."},{"key":"10.4158\/EP12207.OR_bb0015","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1590\/S0004-27302006000400011","article-title":"From mild to severe primary hyperparathyroidism: The Brazilian experience","volume":"50","author":"Bandeira","year":"2006","journal-title":"Arq Bras Endocrinol Metabol"},{"key":"10.4158\/EP12207.OR_bb0020","first-page":"N117","article-title":"Non-classical target organs in primary hyperparathyroidism.","volume":"17","author":"Silverberg","year":"2002","journal-title":"J Bone Miner Res."},{"key":"10.4158\/EP12207.OR_bb0025","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s10554-008-9369-2","article-title":"Evaluation of subclinical coronary atherosclerosis in mild asymptomatic primary hyperparathyroidism patients.","volume":"25","author":"Kepez","year":"2009","journal-title":"Int J Cardiovasc Imaging."},{"key":"10.4158\/EP12207.OR_bb0030","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3109\/10641960903254471","article-title":"Garrido D. Long-term effects of parathyroidectomy on hypertension prevalence and circadian blood pressure profile in primary hyperparathyroidism.","volume":"32","author":"Feldstein","year":"2010","journal-title":"Clin Exp Hypertens."},{"key":"10.4158\/EP12207.OR_bb0035","doi-asserted-by":"crossref","first-page":"3849","DOI":"10.1210\/jc.2009-1086","article-title":"Carotid vascular abnormalities in primary hyperparathyroidism.","volume":"94","author":"Walker","year":"2009","journal-title":"J Clin Endocrinol Metab."},{"key":"10.4158\/EP12207.OR_bb0040","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1530\/EJE-09-1067","article-title":"Cardiovascular risk factors and arterial rigidity are similar in asymptomatic normocalcemic and hypercalcemic primary hyperparathyroidism.","volume":"162","author":"Tordjman","year":"2010","journal-title":"Eur J Endocrinol."},{"key":"10.4158\/EP12207.OR_bb0045","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.3748\/wjg.v16.i23.2959","article-title":"Acute necrotizing pancreatitis as first manifestation of primary hyperparathyroidism.","volume":"16","author":"Lenz","year":"2010","journal-title":"World J Gastroenterol."},{"key":"10.4158\/EP12207.OR_bb0050","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.jchir.2009.06.016","article-title":"Acute pancreatitis and primary hyperparathyroidism: a multicentric study by the Francophone Association of Endocrine Surgeons.","volume":"146","author":"Curto","year":"2009","journal-title":"J Chir (Paris)."},{"key":"10.4158\/EP12207.OR_bb0055","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1111\/j.1464-5491.2009.02804.x","article-title":"Insulin resistance is not coupled with defective insulin secretion in primary hyperparathyroidism.","volume":"26","author":"Tassone","year":"2009","journal-title":"Diabet Med"},{"key":"10.4158\/EP12207.OR_bb0060","doi-asserted-by":"crossref","first-page":"69","DOI":"10.4158\/EP.14.1.69","article-title":"Prevalence of type 2 diabetes mellitus in patients with primary hyperparathyroidism.","volume":"14","author":"Cardenas","year":"2008","journal-title":"Endocr Pract."},{"key":"10.4158\/EP12207.OR_bb0065","doi-asserted-by":"crossref","first-page":"4260","DOI":"10.1210\/jc.2005-2825","article-title":"Changes in insulin sensitivity and glucose and bone metabolism over time in patients with asymptomatic primary hyperparathyroidism.","volume":"91","author":"Ayturk","year":"2006","journal-title":"J Clin Endocrinol Metab."},{"key":"10.4158\/EP12207.OR_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/CCO.0b013e32801173fb","article-title":"Psychiatric and cognitive aspects of primary hyperparathyroidism.","volume":"19","author":"Roman","year":"2007","journal-title":"Curr Opin Oncol."},{"key":"10.4158\/EP12207.OR_bb0075","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1017\/S1355617709990695","article-title":"Cognitive and affective sequelae of primary hyperparathyroidism and early response to parathyroidectomy.","volume":"15","author":"Benge","year":"2009","journal-title":"J Int Neuropsychol Soc"},{"key":"10.4158\/EP12207.OR_bb0080","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1046\/j.0300-0664.2001.01468.x","article-title":"Normalized dyslipidaemia after parathyroidectomy in mild primary hyperparathyroidism: population-based study over five years","volume":"56","author":"Hagstr\u00e2m","year":"2002","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.4158\/EP12207.OR_bb0085","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1136\/bmj.327.7414.530","article-title":"Cohort study on effects of parathyroid surgery on multiple outcomes in primary hyperparathyroidism.","volume":"327","author":"Vestergaard","year":"2003","journal-title":"BMJ."},{"key":"10.4158\/EP12207.OR_bb0090","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/BF03346518","article-title":"Endothelial function and endothelial nitric oxide synthase intron 4a\/b polymorphism in primary hyperparathyroidism.","volume":"32","author":"Ekmekci","year":"2009","journal-title":"J Endocrinol Invest"},{"key":"10.4158\/EP12207.OR_bb0095","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1210\/jc.2008-1760","article-title":"Presentation of asymptomatic primary hyperparathyroidsm: Proceedings of the Third International Workshop.","volume":"94","author":"Silverberg","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP12207.OR_bb0100","first-page":"247","article-title":"Polyneuropathy in type I multiple endocrine syndrome","volume":"19","author":"Conri","year":"1990","journal-title":"Presse Med"},{"key":"10.4158\/EP12207.OR_bb0105","first-page":"1443","article-title":"Severe sensorimotor polyneuropathy in primary hyperparathyroidism","volume":"33","author":"Moskal","year":"1999","journal-title":"Neurol Neurochir Pol."},{"key":"10.4158\/EP12207.OR_bb0110","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/j.1532-5415.1993.tb07468.x","article-title":"Severe neuropathy related to primary hyperparathyroidism cured by parathyroidectomy.","volume":"41","author":"Gentric","year":"1993","journal-title":"J Am Geriatr Soc."},{"key":"10.4158\/EP12207.OR_bb0115","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1007\/BF02427562","article-title":"Reversible combined cognitive impairment and severe polyneuropathy resulting from primary hyperparathyroidism.","volume":"19","author":"Logullo","year":"1998","journal-title":"Ital J Neurol Sci."},{"key":"10.4158\/EP12207.OR_bb0120","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1177\/146642409811800211","article-title":"Lessons to be learned: a case study approach. Primary hyperparathyroidism simulating an acute severe polyneuritis.","volume":"118","author":"Olukoga","year":"1998","journal-title":"J R Soc Health."},{"key":"10.4158\/EP12207.OR_bb0125","first-page":"296","article-title":"Polyneuropathy in a case of primary hyperparathyroidism: disappearance of the neurological picture after surgical correction of the hyperparathyroidism.","volume":"35","author":"Gerster","year":"1970","journal-title":"Helv Med Acta."},{"key":"10.4158\/EP12207.OR_bb0130","first-page":"976","article-title":"Peripheral polyneruropathy associated with primary hyperparathyroidism.","volume":"52","author":"Eufrazino","year":"2008","journal-title":"Arq Bras Endocrinol Metab"},{"key":"10.4158\/EP12207.OR_bb0135","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0002-9343(89)80613-8","article-title":"Neuromuscular involvement in mild, asymptomatic primary hyperparathyroidism","volume":"87","author":"Turken","year":"1989","journal-title":"Am J Med"},{"key":"10.4158\/EP12207.OR_bb0140","doi-asserted-by":"crossref","first-page":"74","DOI":"10.5694\/j.1326-5377.1988.tb120508.x","article-title":"Neuromuscular symptoms in elderly patients with hyperparathyroidism: improvement with parathyroid surgery","volume":"149","author":"Delbridge","year":"1988","journal-title":"Med J Aust"},{"key":"10.4158\/EP12207.OR_bb0145","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0039-6060(05)80224-7","article-title":"Neuromuscular recovery after parathyroidectomy in primary hyperparathyroidism","volume":"117","author":"Chou","year":"1995","journal-title":"Surgery"},{"key":"10.4158\/EP12207.OR_bb0150","doi-asserted-by":"crossref","first-page":"83","DOI":"10.14310\/horm.2002.1225","article-title":"Medical treatment of hypercalcaemia","volume":"8","author":"Makras","year":"2009","journal-title":"Hormones (Athens)"},{"key":"10.4158\/EP12207.OR_bb0155","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/MCG.0b013e3181cd9d4c","article-title":"The parathyroids and the gut","volume":"44","author":"Ebert","year":"2010","journal-title":"J Clin Gastroenterol"},{"key":"10.4158\/EP12207.OR_bb0160","first-page":"IA","article-title":"Search for the uremic toxin: parathormone levels and nerve conduction in man","volume":"10","author":"Avram","year":"1977","journal-title":"Proc Am Soc Nephrol"},{"key":"10.4158\/EP12207.OR_bb0165","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1172\/JCI109118","article-title":"Effect of parathyroid hormone and uremia on peripheral nerve calcium and motor nerve conduction velocity","volume":"62","author":"Goldstein","year":"1978","journal-title":"J Clin Invest"},{"key":"10.4158\/EP12207.OR_bb0170","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1083\/jcb.59.2.456","article-title":"Effects of calcium ion concentration on the degeneration of amputated axons in tissue culture","volume":"59","author":"Schlaepfer","year":"1973","journal-title":"J Cell Biol"},{"key":"10.4158\/EP12207.OR_bb0175","doi-asserted-by":"crossref","first-page":"R147","DOI":"10.1186\/cc9215","article-title":"Treatment of hypophosphatemia in the intensive care unit: a review","volume":"14","author":"Geerse","year":"2010","journal-title":"Crit Care"},{"key":"10.4158\/EP12207.OR_bb0180","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1002\/(SICI)1097-4598(199805)21:5<650::AID-MUS14>3.0.CO;2-Z","article-title":"Hypophosphatemia-induced neuropathy: clinical and electrophysiologic findings","volume":"21","author":"Siddiqui","year":"1998","journal-title":"Muscle Nerve"},{"key":"10.4158\/EP12207.OR_bb0185","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1136\/jnnp.2006.108720","article-title":"Hypophosphataemic neuropathy in a patient who received intravenous hyperalimentation","volume":"78","author":"Iguchi","year":"2007","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.4158\/EP12207.OR_bb0190","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1136\/jnnp.65.6.810","article-title":"Neurology and the kidney","volume":"65","author":"Burn","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.4158\/EP12207.OR_bb0195","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1152\/physrev.1977.57.3.421","article-title":"Relationships between calcium and cyclic nucleotides in cell activation","volume":"57","author":"Rasmussen","year":"1977","journal-title":"Physiol Rev"},{"key":"10.4158\/EP12207.OR_bb0200","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0003-9861(74)90486-X","article-title":"Calcium-binding phosphoprotein from pig brain: Identification as a calcium-dependent regulator of brain cyclic nucleotide phosphodiesterase","volume":"163","author":"Wolff","year":"1974","journal-title":"Arch Biochem Biophys"},{"key":"10.4158\/EP12207.OR_bb0205","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.prp.2010.09.006","article-title":"Parathyroid hormone(1-34)-induced apoptosis in neuronal rat PC12 cells: implications for neurotoxicity","volume":"206","author":"An","year":"2010","journal-title":"Pathol Res Pract"}],"container-title":["Endocrine Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X20404604?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X20404604?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/aace.metapress.com\/index\/3J1674242761124U.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:56:15Z","timestamp":1761515775000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1530891X20404604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["S1530891X20404604"],"URL":"https:\/\/doi.org\/10.4158\/ep12207.or","relation":{},"ISSN":["1530-891X"],"issn-type":[{"value":"1530-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Primary Hyperparathyroidism is Associated With subclinical Peripheral Neural Alterations","name":"articletitle","label":"Article Title"},{"value":"Endocrine Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.4158\/EP12207.OR","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}