{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:45:46Z","timestamp":1791297946501,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["aacejournalendocrinepractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrine Practice"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.4158\/ep171914.ra","type":"journal-article","created":{"date-parts":[[2017,6,14]],"date-time":"2017-06-14T16:05:31Z","timestamp":1497456331000},"page":"999-1005","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["The Physiology Behind Diabetes Mellitus in Patients with Pheochromocytoma: A Review of the Literature"],"prefix":"10.1016","volume":"23","author":[{"given":"Bayan","family":"Mesmar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silpa","family":"Poola- Kella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana","family":"Malek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.4158\/EP171914.RA_bb0010","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1210\/jc.2014-1498","article-title":"Pheochromocytoma and paraganglioma: an Endocrine Society clinical practice guideline","volume":"99","author":"Lenders","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP171914.RA_bb0015","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1097\/01.hjh.0000251887.01885.54","article-title":"Pheochromocytoma: presentation, diagnosis and treatment","volume":"24","author":"Reisch","year":"2006","journal-title":"J Hypertens"},{"key":"10.4158\/EP171914.RA_bb0020","article-title":"Phaeochromocytoma and diabetes mellitus","author":"Groups","year":"2014","journal-title":"Diapedia"},{"key":"10.4158\/EP171914.RA_bb0025","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S0140-6736(66)92986-2","article-title":"Inhibition of insulin secretion by a phaeochromocytoma","volume":"2","author":"Wilber","year":"1966","journal-title":"Lancet"},{"key":"10.4158\/EP171914.RA_bb0030","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1172\/JCI105335","article-title":"The effect of epinephrine on immunoreactive insulin levels in man","volume":"45","author":"Porte","year":"1966","journal-title":"J Clin Invest"},{"key":"10.4158\/EP171914.RA_bb0035","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1742-7843.2011.00699.x","article-title":"\u03b12-Adrenoceptor regulation of blood glucose homeostasis","volume":"108","author":"Fagerholm","year":"2011","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"10.4158\/EP171914.RA_bb0040","doi-asserted-by":"crossref","first-page":"692","DOI":"10.2337\/db11-1027","article-title":"Age-related impairment in insulin release: the essential role of \u03b22-adrenergic receptor","volume":"61","author":"Santulli","year":"2012","journal-title":"Diabetes"},{"key":"10.4158\/EP171914.RA_bb0045","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1159\/000334629","article-title":"Involvement of \u03b12-adrenoceptor subtypes A and C in glucose homeostasis and adrenaline-induced hyperglycaemia","volume":"96","author":"Ruohonen","year":"2012","journal-title":"Neuroendocrinology"},{"key":"10.4158\/EP171914.RA_bb0050","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.clinbiochem.2013.02.004","article-title":"Association of the ADRA2A polymorphisms with the risk of type 2 diabetes: a meta-analysis","volume":"46","author":"Chen","year":"2013","journal-title":"Clin Biochem"},{"key":"10.4158\/EP171914.RA_bb0055","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1172\/JCI110451","article-title":"Mechanisms of epinephrine-induced glucose intolerance in normal humans","volume":"69","author":"Sacc\u00e0","year":"1982","journal-title":"J Clin Invest"},{"key":"10.4158\/EP171914.RA_bb0060","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1172\/JCI109718","article-title":"Epinephrine-induced insulin resistance in man","volume":"65","author":"Deibert","year":"1980","journal-title":"J Clin Invest"},{"key":"10.4158\/EP171914.RA_bb0065","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/414799a","article-title":"Insulin signaling and the regulation of glucose and lipid metabolism","volume":"414","author":"Saltiel","year":"2001","journal-title":"Nature"},{"key":"10.4158\/EP171914.RA_bb0070","first-page":"E700","article-title":"Epinephrine translocates GLUT-4 but inhibits insulin-stimulated glucose transport in rat muscle","volume":"274","author":"Han","year":"1998","journal-title":"Am J Physiol"},{"key":"10.4158\/EP171914.RA_bb0075","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0006-291X(92)91249-P","article-title":"Epinephrine administration stimulates GLUT4 translocation but reduces glucose transport in muscle","volume":"187","author":"Bonen","year":"1992","journal-title":"Biochem Biophys Res Commun"},{"key":"10.4158\/EP171914.RA_bb0080","doi-asserted-by":"crossref","first-page":"566","DOI":"10.7326\/0003-4819-93-4-566","article-title":"Influence of small increments of epinephrine in glucose tolerance in normal humans","volume":"93","author":"Hamburg","year":"1980","journal-title":"Ann Intern Med"},{"key":"10.4158\/EP171914.RA_bb0085","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1152\/japplphysiol.00003.2014","article-title":"Adrenergic control of lipolysis in women compared with men","volume":"117","author":"Schmidt","year":"2014","journal-title":"J Appl Physiol (1985)"},{"key":"10.4158\/EP171914.RA_bb0090","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.cellsig.2016.06.018","article-title":"Metformin and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue","volume":"28","author":"Zhao","year":"2016","journal-title":"Cell Signal"},{"key":"10.4158\/EP171914.RA_bb0095","doi-asserted-by":"crossref","first-page":"17450","DOI":"10.1073\/pnas.1410530111","article-title":"Catecholamine-induced lipolysis causes mTOR complex dissociation and inhibits glucose uptake in adipocytes","volume":"111","author":"Mullins","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.4158\/EP171914.RA_bb0100","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/BF03401534","article-title":"Adiponectin: regulation of its production and its role in human diseases","volume":"11","author":"Shehzad","year":"2012","journal-title":"Hormones (Athens)"},{"key":"10.4158\/EP171914.RA_bb0105","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1467-789X.2005.00159.x","article-title":"Adiponectin: action, regulation and association to insulin sensitivity","volume":"6","author":"Lihn","year":"2005","journal-title":"Obes Rev"},{"key":"10.4158\/EP171914.RA_bb0110","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.cyto.2010.03.011","article-title":"Adiponectin\u2014a possible factor in the pathogenesis of carbohydrate metabolism disturbances in patients with pheochromocytoma","volume":"50","author":"Elenkova","year":"2010","journal-title":"Cytokine"},{"key":"10.4158\/EP171914.RA_bb0115","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1172\/JCI105514","article-title":"A Receptor Mechanism for the inhibition of insulin release by epinephrine in man","volume":"46","author":"Porte","year":"1967","journal-title":"J Clin Invest"},{"key":"10.4158\/EP171914.RA_bb0120","doi-asserted-by":"crossref","first-page":"61","DOI":"10.14310\/horm.2002.1184","article-title":"Insulin resistance in pheochromocytoma improves more by surgical rather than by medical treatment","volume":"2","author":"Diamanti-Kandarakis","year":"2003","journal-title":"Hormones (Athens)"},{"key":"10.4158\/EP171914.RA_bb0125","doi-asserted-by":"crossref","first-page":"3632","DOI":"10.1210\/jc.2003-030000","article-title":"Improvement of insulin sensitivity after adrenalectomy in patients with pheochromocytoma","volume":"88","author":"Wiesner","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP171914.RA_bb0130","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1007\/s00268-005-7839-4","article-title":"Normotensive pheochromocytoma: institutional experience","volume":"29","author":"Agarwal","year":"2005","journal-title":"World J Surg"},{"key":"10.4158\/EP171914.RA_bb0135","first-page":"E608","article-title":"Vasoactive intestinal peptide inhibits insulin-stimulated glucose transport in rat adipocytes","volume":"249","author":"Green","year":"1985","journal-title":"Am J Physiol"},{"key":"10.4158\/EP171914.RA_bb0140","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1046\/j.1365-2265.1997.1160931.x","article-title":"Interleukin-6 secreting phaeochromocytoma associated with clinical markers of inflammation","volume":"46","author":"Takagi","year":"1997","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.4158\/EP171914.RA_bb0145","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/BF03345202","article-title":"Interleukin-6 producing pheochromocytoma presenting with acute inflammatory syndrome","volume":"26","author":"Minetto","year":"2003","journal-title":"J Endocrinol Invest"},{"key":"10.4158\/EP171914.RA_bb0150","doi-asserted-by":"crossref","first-page":"2952","DOI":"10.1210\/jc.2009-0309","article-title":"Overexpression of interleukin-13 receptor-alpha2 in neuroendocrine malignant pheochromocytoma: a novel target for receptor directed anti-cancer therapy","volume":"94","author":"Lai","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP171914.RA_bb0155","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.cyto.2016.06.028","article-title":"Adiponectin, TNF-\u03b1 and inflammatory cytokines and risk of type 2 diabetes: a systematic review and meta-analysis","volume":"86","author":"Liu","year":"2016","journal-title":"Cytokine"},{"key":"10.4158\/EP171914.RA_bb0160","doi-asserted-by":"crossref","first-page":"321","DOI":"10.3892\/ol.2015.3222","article-title":"Nonfunctioning paraganglioma occurring in the urinary bladder: a case report and review of the literature","volume":"10","author":"Peng","year":"2015","journal-title":"Oncol Lett"},{"key":"10.4158\/EP171914.RA_bb0165","first-page":"341","article-title":"Paraganglioma: A potentially challenging tumor. See comment in PubMed Commons","volume":"22","author":"Trombetta","year":"2008","journal-title":"Oncology (Williston Park)"},{"key":"10.4158\/EP171914.RA_bb0170","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0079-6123(10)82015-1","article-title":"Pheochromocytoma and paraganglioma","volume":"182","author":"Kantorovich","year":"2010","journal-title":"Prog Brain Res"},{"key":"10.4158\/EP171914.RA_bb0175","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1016\/S0026-0495(97)90146-3","article-title":"The effect of norepinephrine on insulin secretion and glucose effectiveness in non-insulin-dependent diabetes","volume":"46","author":"Walters","year":"1997","journal-title":"Metabolism"},{"key":"10.4158\/EP171914.RA_bb0180","doi-asserted-by":"crossref","first-page":"E58","DOI":"10.1152\/ajpendo.00517.2013","article-title":"Enhanced insulin secretion responsiveness and islet adrenergic desensitization after chronic norepinephrine suppression is discontinued in fetal sheep","volume":"306","author":"Chen","year":"2014","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.4158\/EP171914.RA_bb0185","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1172\/JCI109576","article-title":"Vascular and metabolic effects of circulating epinephrine and norepinephrine. Concentration-effect study in dogs","volume":"64","author":"Hjemdahl","year":"1979","journal-title":"J Clin Invest"},{"key":"10.4158\/EP171914.RA_bb0190","first-page":"E674","article-title":"Role of epinephrine and norepinephrine in the metabolic response to stress hormone infusion in the conscious dog","volume":"273","author":"McGuinness","year":"1997","journal-title":"Am J Physiol"},{"key":"10.4158\/EP171914.RA_bb0195","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1172\/JCI103310","article-title":"A comparison of the metabolic and circulatory effects of epinephrine, nor-epinephrine and insulin hypoglycemia with observations on the influence of autonomic blocking agents","volume":"35","author":"DiSalvo","year":"1956","journal-title":"J Clin Invest"},{"key":"10.4158\/EP171914.RA_bb0200","doi-asserted-by":"crossref","first-page":"E949","DOI":"10.1152\/ajpendo.2000.278.5.E949","article-title":"Epinephrine infusion during moderate intensity exercise increases glucose production and uptake","volume":"278","author":"Kreisman","year":"2000","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.4158\/EP171914.RA_bb0205","first-page":"2118","article-title":"Norepinephrine infusion during moderate-intensity exercise increases glucose production and uptake","volume":"86","author":"Kreisman","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP171914.RA_bb0210","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1479-828X.2005.00344.x","article-title":"Diabetes mellitus as the only manifestation of occult phaeochromocytoma prior to acute haemorrhage in pregnancy","volume":"45","author":"Tong","year":"2005","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.4158\/EP171914.RA_bb0215","first-page":"145","article-title":"Beta adrenergic blockers: pharmacological and anesthetic considerations","volume":"52","author":"Sandra","year":"1984","journal-title":"Am Assoc Nurse Anesth J"},{"key":"10.4158\/EP171914.RA_bb0220","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.2174\/1381612013397339","article-title":"Beta 3-adrenoceptor agonists as anti-diabetic and anti-obesity drugs in humans","volume":"7","author":"de Souza","year":"2001","journal-title":"Curr Pharm Des"},{"issue":"6 suppl","key":"10.4158\/EP171914.RA_bb0225","doi-asserted-by":"crossref","first-page":"S313","DOI":"10.1067\/mai.2002.129702","article-title":"Beta-agonists and metabolism","volume":"110","author":"Philipson","year":"2002","journal-title":"J Allergy Clin Immunol"}],"container-title":["Endocrine Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X20358547?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X20358547?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:03:57Z","timestamp":1761516237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1530891X20358547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":44,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["S1530891X20358547"],"URL":"https:\/\/doi.org\/10.4158\/ep171914.ra","relation":{},"ISSN":["1530-891X"],"issn-type":[{"value":"1530-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Physiology Behind Diabetes Mellitus in Patients with Pheochromocytoma: A Review of the Literature","name":"articletitle","label":"Article Title"},{"value":"Endocrine Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.4158\/EP171914.RA","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}