{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T18:17:38Z","timestamp":1772734658427,"version":"3.50.1"},"reference-count":20,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["aacejournalendocrinepractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrine Practice"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.4158\/ep171964.or","type":"journal-article","created":{"date-parts":[[2017,8,17]],"date-time":"2017-08-17T10:56:13Z","timestamp":1502967373000},"page":"1325-1332","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Seven Familial Dysalbuminemic Hyperthyroxinemia Cases in Three Unrelated Japanese Families and High-Performance Liquid Chromatography Analysis of the Thyroxine Binding Profile"],"prefix":"10.1016","volume":"23","author":[{"given":"Hidekazu","family":"Nagano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naofumi","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroya","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yui","family":"Miyabayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akitoshi","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eri","family":"Komai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akina","family":"Shiga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Kono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Takiguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiichiro","family":"Higuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikki","family":"Sakuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoko","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sawako","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Koide","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koutaro","family":"Yokote","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoaki","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.4158\/EP171964.OR_bb0010","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S0140-6736(79)91080-8","article-title":"Raised total thyroxine and free thyroxine index but normal free thyroxine. A serum abnormality due to inherited increased affinity of iodothyronines for serum binding protein","volume":"1","author":"Hennemann","year":"1979","journal-title":"Lancet"},{"key":"10.4158\/EP171964.OR_bb0015","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1210\/jcem-49-2-292","article-title":"Inherited abnormal thyroid hormone-binding protein causing selective increase of total serum thyroxine","volume":"49","author":"Lee","year":"1979","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP171964.OR_bb0020","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1006\/bbrc.1994.1998","article-title":"An identical missense mutation in the albumin gene results in familial dysalbuminemic hyperthyroxinemia in 8 unrelated families","volume":"202","author":"Sunthornthepvarakul","year":"1994","journal-title":"Biochem Biophys Res Commun"},{"key":"10.4158\/EP171964.OR_bb0025","doi-asserted-by":"crossref","first-page":"19110","DOI":"10.1074\/jbc.271.32.19110","article-title":"Mutations in a specific human serum albumin thyroxine binding site define the structural basis of familial dysalbuminemic hyperthyroxinemia","volume":"271","author":"Petersen","year":"1996","journal-title":"J Biol Chem"},{"key":"10.4158\/EP171964.OR_bb0030","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1136\/bmj.290.6475.1099","article-title":"Detection of familial dysalbuminaemic hyperthyroxinaemia","volume":"290","author":"Croxson","year":"1985","journal-title":"Br Med J (Clin Res Ed)"},{"key":"10.4158\/EP171964.OR_bb0035","doi-asserted-by":"crossref","first-page":"3246","DOI":"10.1210\/jcem.82.10.4276","article-title":"A novel missense mutation in codon 218 of the albumin gene in a distinct phenotype of familial dysalbuminemic hyperthyroxinemia in a Japanese kindred","volume":"82","author":"Wada","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP171964.OR_bb0040","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1056\/NEJM198203183061103","article-title":"Familial dysalbuminemic hyperthyroxinemia: a syndrome that can be confused with thyrotoxicosis","volume":"306","author":"Ruiz","year":"1982","journal-title":"N Engl J Med"},{"key":"10.4158\/EP171964.OR_bb0045","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1530\/eje.0.1330729","article-title":"Familial dysalbuminemic hyperthyroxinemia in pregnancy","volume":"133","author":"Sachmechi","year":"1995","journal-title":"Eur J Endocrinol"},{"key":"10.4158\/EP171964.OR_bb0050","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1177\/014107688808100116","article-title":"Familial dysalbuminaemic hyperthyroxinaemia: a review","volume":"81","author":"Jensen","year":"1988","journal-title":"J R Soc Med"},{"key":"10.4158\/EP171964.OR_bb0055","first-page":"2786","article-title":"Familial dysalbuminemic hyperthyroxinemia in a Swiss family caused by a mutant albumin (R218P) shows an apparent discrepancy between serum concentration and affinity for thyroxine","volume":"85","author":"Pannain","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP171964.OR_bb0060","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1093\/clinchem\/30.7.1179","article-title":"Familial dysalbuminemic hyperthyroxinemia: a study of four probands and the kindred of three","volume":"30","author":"Scottolini","year":"1984","journal-title":"Clin Chem"},{"key":"10.4158\/EP171964.OR_bb0065","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1136\/jmg.31.5.355","article-title":"A point mutation in the human serum albumin gene results in familial dysalbuminaemic hyperthyroxinaemia","volume":"31","author":"Petersen","year":"1994","journal-title":"J Med Genet"},{"key":"10.4158\/EP171964.OR_bb0070","doi-asserted-by":"crossref","first-page":"780","DOI":"10.7326\/0003-4819-107-5-780_2","article-title":"Prevalence of familial dysalbuminemic hyperthyroxinemia in Hispanics","volume":"107","author":"DeCosimo","year":"1987","journal-title":"Ann Intern Med"},{"key":"10.4158\/EP171964.OR_bb0075","first-page":"464","article-title":"A Chinese family with familial dysalbuminaemic hyperthyroxinaemia","volume":"9","author":"Tiu","year":"2003","journal-title":"Hong Kong Med J"},{"key":"10.4158\/EP171964.OR_bb0080","first-page":"1448","article-title":"Familial dysalbuminemic hypertriiodothyroninemia: a new, dominantly inherited albumin defect","volume":"83","author":"Sunthornthepvarakul","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP171964.OR_bb0085","doi-asserted-by":"crossref","first-page":"E1381","DOI":"10.1210\/jc.2013-4077","article-title":"A novel albumin gene mutation (R222I) in familial dysalbuminemic hyperthyroxinemia","volume":"99","author":"Schoenmakers","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4158\/EP171964.OR_bb0090","doi-asserted-by":"crossref","first-page":"6440","DOI":"10.1073\/pnas.1137188100","article-title":"Structural basis of albumin-thyroxine interactions and familial dysalbuminemic hyperthyroxinemia","volume":"100","author":"Petitpas","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.4158\/EP171964.OR_bb0095","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1093\/clinchem\/32.4.687","article-title":"Concentration of free thyroxin in serum of a patient with euthyroid hyperthyroxinemia secondary to increased thyroxin-binding prealbumin: results by various methods compared","volume":"32","author":"Skiest","year":"1986","journal-title":"Clin Chem"},{"key":"10.4158\/EP171964.OR_bb0100","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1373\/clinchem.2010.158170","article-title":"Spuriously high free thyroxine values in familial dysalbuminemic hyperthyroxinemia","volume":"57","author":"Ross","year":"2011","journal-title":"Clin Chem"},{"key":"10.4158\/EP171964.OR_bb0105","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1373\/clinchem.2008.120303","article-title":"Familial dysalbuminemic hyperthyroxinemia: a persistent diagnostic challenge","volume":"55","author":"Cartwright","year":"2009","journal-title":"Clin Chem"}],"container-title":["Endocrine Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X2035223X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X2035223X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:02:59Z","timestamp":1761516179000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1530891X2035223X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["S1530891X2035223X"],"URL":"https:\/\/doi.org\/10.4158\/ep171964.or","relation":{},"ISSN":["1530-891X"],"issn-type":[{"value":"1530-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Seven Familial Dysalbuminemic Hyperthyroxinemia Cases in Three Unrelated Japanese Families and High-Performance Liquid Chromatography Analysis of the Thyroxine Binding Profile","name":"articletitle","label":"Article Title"},{"value":"Endocrine Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.4158\/EP171964.OR","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}