{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:39:44Z","timestamp":1789540784177,"version":"build-2803163510"},"reference-count":137,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Communicative & Integrative Biology"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.4161\/cib.17602","type":"journal-article","created":{"date-parts":[[2014,7,17]],"date-time":"2014-07-17T18:26:23Z","timestamp":1405621583000},"page":"640-654","source":"Crossref","is-referenced-by-count":15,"title":["A new theoretical approach to the functional meaning of sleep and dreaming in humans based on the maintenance of \u2018predictive psychic homeostasis\u2019"],"prefix":"10.1080","volume":"4","author":[{"given":"Luigi F.","family":"Agnati","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W.","family":"Barlow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franti\u0161ek","family":"Balu\u0161ka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Tonin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Guescini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppina","family":"Leo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjell","family":"Fuxe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2014,10,28]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1038\/nrn2521","article-title":"Sleep as a fundamental property of neuronal assemblies","volume":"9","author":"Krueger","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"R2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0079-6123(00)25003-6","article-title":"Volume transmission as a key feature of information handling in the central nervous system possible new interpretative value of the Turing's B-type machine","volume":"125","author":"Agnati","year":"2000","journal-title":"Prog Brain Res"},{"key":"R3","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.pneurobio.2009.10.012","article-title":"The discovery of central monoamine neurons gave volume transmission to the wired brain","volume":"90","author":"Fuxe","year":"2010","journal-title":"Prog Neurobiol"},{"key":"R4","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1126\/science.1195027","article-title":"Circadian Integration of Metabolism and Energetics","volume":"330","author":"Bass","year":"2010","journal-title":"Science"},{"key":"R5","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/BF00711551","article-title":"Pontogeniculooccipital waves: spontaneous visual system activity during rapid eye movement sleep","volume":"7","author":"Callaway","year":"1987","journal-title":"Cell Mol Neurobiol"},{"key":"R6","unstructured":"Rechtschaffen A, Kales A. A manual of standardized terminology, techniques and scoring system of sleep stages in human subjects editors. In: Rechtschaffen A, Kales ed, Los Angeles: Brain Information Service\/Brain Research Institute, University of California, 1968."},{"key":"R7","first-page":"1","article-title":"Coalescence of sleep rhythms and their chronology in corticothalamic networks","volume":"1","author":"Steriade","year":"1998","journal-title":"Sleep Res Online"},{"key":"R8","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1073\/pnas.90.5.2078","article-title":"Coherent 40-Hz oscillation characterizes dream state in humans","volume":"90","author":"Llin\u00e1s","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"R9","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1523\/JNEUROSCI.16-01-00392.1996","article-title":"Synchronization of fast (30-40 Hz) spontaneous cortical rhythms during brain activation","volume":"16","author":"Steriade","year":"1996","journal-title":"J Neurosci"},{"key":"R10","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1126\/science.1094539","article-title":"Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups","volume":"189","author":"Hobson","year":"1975","journal-title":"Science"},{"key":"R11","unstructured":"Lydic R, Baghdoyan HA. Handbook of behavioural state control: Cellular and molecular mechanisms. Buca Raton, FL: CRC Press, 1988."},{"key":"R12","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0024-3205(90)90300-G","article-title":"Alterations in acetylcholine release in the rat hippocampus during sleep-wakefulness detected by intracerebral dialysis","volume":"47","author":"Kametani","year":"1990","journal-title":"Life Sci"},{"key":"R13","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0006-8993(94)01399-3","article-title":"Microdialysis measurement of cortical and hippocampal acetylcholine release during sleep-wake cycle in freely moving cats","volume":"671","author":"Marrosu","year":"1995","journal-title":"Brain Res"},{"key":"R14","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.physbeh.2007.05.034","article-title":"Adenosine receptor-dopamine receptor interactions in the basal ganglia and their relevance for brain function","volume":"92","author":"Fuxe","year":"2007","journal-title":"Physiol Behav"},{"key":"R15","first-page":"166","article-title":"The role of monoamines and acetylcholine-containing neurons in the regulation of the sleep-waking cycle","volume":"64","author":"Jouvet","year":"1972","journal-title":"Ergeb Physiol"},{"key":"R16","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0006-8993(77)90521-2","article-title":"The effects of 5,7-dihydroxytryptamine-induced lesions of the ascending 5-hydroxytryptamine pathways on the sleep wakefulness cycle","volume":"131","author":"Kiianmaa","year":"1977","journal-title":"Brain Res"},{"key":"R17","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0304-3940(78)90097-6","article-title":"5-Hydroxytryptamine neurons and the sleep-wakefulness cycle. Effects of methergoline and zimelidine","volume":"8","author":"Fuxe","year":"1978","journal-title":"Neurosci Lett"},{"key":"R18","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1523\/JNEUROSCI.01-08-00876.1981","article-title":"Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle","volume":"1","author":"Aston-Jones","year":"1981","journal-title":"J Neurosci"},{"key":"R19","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0006-8993(86)91522-2","article-title":"Firing properties of two types of nucleus raphe dorsalis neurons during the sleep-waking cycle and their responses to sensory stimuli","volume":"399","author":"Shima","year":"1986","journal-title":"Brain Res"},{"key":"R20","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/nrn915","article-title":"The cognitive neuroscience of sleep: neuronal systems, consciousness and learning","volume":"3","author":"Hobson","year":"2002","journal-title":"Nat Rev Neurosci"},{"key":"R21","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.smrv.2004.07.003","article-title":"Neuroimaging and sleep medicine","volume":"9","author":"Nofzinger","year":"2005","journal-title":"Sleep Med Rev"},{"key":"R22","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1037\/a0016570","article-title":"Overnight therapy? The role of sleep in emotional brain processing","volume":"135","author":"Walker","year":"2009","journal-title":"Psychol Bull"},{"key":"R23","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0074-7742(10)92004-7","article-title":"REM and NREM sleep mentation","volume":"92","author":"McNamara","year":"2010","journal-title":"Int Rev Neurobiol"},{"key":"R24","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1111\/j.1558-5646.2008.00392.x","article-title":"Phylogenetic analysis of the ecology and evolution of mammalian sleep","volume":"62","author":"Capellini","year":"2008","journal-title":"Evolution"},{"key":"R25","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/nrn2697","article-title":"Sleep viewed as a state of adaptive inactivity","volume":"10","author":"Siegel","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"R26","first-page":"R737","article-title":"Physiology of the circadian timing system: predictive versus reactive homeostasis","volume":"250","author":"Moore-Ede","year":"1986","journal-title":"Am J Physiol"},{"key":"R27","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/sleep\/33.1.113","article-title":"Changes in cardiac variability after REM sleep deprivation in recurrent nightmares","volume":"33","author":"Nielsen","year":"2010","journal-title":"Sleep"},{"key":"R28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.janxdis.2009.08.002","article-title":"Temporal relations between sleep problems and both traumatic event exposure and PTSD: a critical review of the empirical literature","volume":"24","author":"Babson","year":"2010","journal-title":"J Anxiety Disord"},{"key":"R29","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.smrv.2007.08.008","article-title":"Disturbed sleep in post-traumatic stress disorder: secondary symptom or core feature?","volume":"12","author":"Spoormaker","year":"2008","journal-title":"Sleep Med Rev"},{"key":"R30","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s12160-009-9101-z","article-title":"Heart rate variability, prefrontal neural function, and cognitive performance: the neurovisceral integration perspective on self-regulation, adaptation, and health","volume":"37","author":"Thayer","year":"2009","journal-title":"Ann Behav Med"},{"key":"R31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.autneu.2005.06.007","article-title":"Power spectrum analysis and cardiovascular morbidity in anxiety disorders","volume":"128","author":"Cohen","year":"2006","journal-title":"Auton Neurosci"},{"key":"R32","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1101\/lm.77104","article-title":"Sleep, dreams, and memory consolidation: The role of the stress hormone cortisol","volume":"11","author":"Payne","year":"2004","journal-title":"Learn Mem"},{"key":"R33","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1196\/annals.1364.015","article-title":"Neuroendocrine regulation of sleep disturbances in PTSD","volume":"1071","author":"Neylan","year":"2006","journal-title":"Ann N Y Acad Sci"},{"key":"R34","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000096362","article-title":"Dreaming in posttraumatic stress disorder: A critical review of phenomenology, psychophysiology and treatment","volume":"76","author":"Wittmann","year":"2007","journal-title":"Psychother Psychosom"},{"key":"R35","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/S0272-7358(03)00032-1","article-title":"Sleep and posttraumatic stress disorder: a review","volume":"23","author":"Harvey","year":"2003","journal-title":"Clin Psychol Rev"},{"key":"R36","unstructured":"Smith H. From the Fish to the Philosopher. Little Brown, Boston, 1953."},{"key":"R37","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1159\/000216184","article-title":"Regulation of the hypothalamic-pituitary-adrenal axis","volume":"16","author":"Papadimitriou","year":"2009","journal-title":"Neuroimmunomodulation"},{"key":"R38","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1037\/a0017773","article-title":"Allostasis and the human brain: Integrating models of stress from the social and life sciences","volume":"117","author":"Ganzel","year":"2010","journal-title":"Psychol Rev"},{"key":"R39","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/304111a0","article-title":"The function of dream sleep","volume":"304","author":"Crick","year":"1983","journal-title":"Nature"},{"key":"R40","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1126\/science.860134","article-title":"Evolution and tinkering","volume":"196","author":"Jacob","year":"1977","journal-title":"Science"},{"key":"R41","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.brainresrev.2007.11.002","article-title":"Understanding neuronal molecular networks builds on neuronal cellular network architecture","volume":"58","author":"Agnati","year":"2008","journal-title":"Brain Res Brain Res Rev"},{"key":"R42","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1017\/S0094837300004310","article-title":"Exaptation\u2013a missing term in the science of form","volume":"8","author":"Gould","year":"1982","journal-title":"Paleobiology"},{"key":"R43","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0079-6123(06)53020-1","article-title":"Organization of circadian functions: interaction with the body","volume":"153","author":"Buijs","year":"2006","journal-title":"Prog Brain Res"},{"key":"R44","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/nrn2647","article-title":"Neural regulation of endocrine and autonomic stress responses","volume":"10","author":"Ulrich-Lai","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"R45","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1007\/s00424-008-0498-1","article-title":"Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption","volume":"456","author":"Boone","year":"2008","journal-title":"Pflugers Arch"},{"key":"R46","first-page":"27","article-title":"Growth hormone-releasing peptides and the cardiovascular system","volume":"61","author":"Muccioli","year":"2000","journal-title":"Ann Endocrinol (Paris)"},{"key":"R47","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/00003677-200110000-00006","article-title":"Muscle afferent-pituitary axis: a novel pathway for modulating the secretion of a pituitary growth factor","volume":"29","author":"McCall","year":"2001","journal-title":"Exerc Sport Sci Rev"},{"key":"R48","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.ecl.2005.01.003","article-title":"Hypothalamic-pituitary-adrenocortical axis regulation","volume":"34","author":"Jacobson","year":"2005","journal-title":"Endocrinol Metab Clin North Am"},{"key":"R49","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1055\/s-0029-1211243","article-title":"Entrainment of nocturnal pituitary-adrenocortical activity to sleep processes in man\u2013a hypothesis","volume":"101","author":"Fehm","year":"1993","journal-title":"Exp Clin Endocrinol"},{"key":"R50","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1053\/smrv.2001.0159","article-title":"Sleep and the hypothalamo\u2013pituitary\u2013adrenocortical system","volume":"6","author":"Steiger","year":"2002","journal-title":"Sleep Med Rev"},{"key":"R51","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1471-244X-3-15","article-title":"The renin-angiotensin-aldosterone system in patients with depression compared to controls\u2013a sleep endocrine study","volume":"3","author":"Murck","year":"2003","journal-title":"BMC Psychiatry"},{"key":"R52","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1159\/000279301","article-title":"Sleep and active renin levels\u2013interaction with age, gender, growth hormone and cortisol","volume":"61","author":"Sch\u00fcssler","year":"2010","journal-title":"Neuropsychobiology"},{"key":"R53","first-page":"E43","article-title":"Aldosterone release during the sleep-wake cycle in humans","volume":"276","author":"Charloux","year":"1999","journal-title":"Am J Physiol"},{"key":"R54","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/mp.2009.46","article-title":"Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep","volume":"15","author":"Kimura","year":"2010","journal-title":"Mol Psychiatry"},{"key":"R55","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0079-6123(00)26011-1","article-title":"The integration of stress by the hypothalamus, amygdala and prefrontal cortex: balance between the autonomic nervous system and the neuroendocrine system","volume":"126","author":"Buijs","year":"2000","journal-title":"Prog Brain Res"},{"key":"R56","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/01.PSY.0000106884.58744.09","article-title":"Acute stress affects heart rate variability during sleep","volume":"66","author":"Hall","year":"2004","journal-title":"Psychosom Med"},{"key":"R57","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1046\/j.1440-1819.2003.01080.x","article-title":"Correlation between electroencephalography and heart rate variability during sleep","volume":"57","author":"Ako","year":"2003","journal-title":"Psychiatry Clin Neurosci"},{"key":"R58","first-page":"H151","article-title":"Assessment of autonomic function in humans by heart rate spectral analysis","volume":"248","author":"Pomeranz","year":"1985","journal-title":"Am J Physiol"},{"key":"R59","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1161\/01.CIR.91.7.1918","article-title":"Ba-Lin, Pinna GD, Lazzara R, Orr WC. Heart rate variability during specific sleep stages. A comparison of healthy subjects with patients after myocardial infarction","volume":"91","author":"Vanoli","year":"1995","journal-title":"Circulation"},{"key":"R60","first-page":"29","article-title":"The utility of spectral analytic techniques in the study of the autonomic regulation of beat-to-beat heart rate variability","volume":"4","author":"Mezzacappa","year":"1994","journal-title":"Int J Met Psych Res"},{"key":"R61","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1161\/01.RES.59.2.178","article-title":"Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog","volume":"59","author":"Pagani","year":"1986","journal-title":"Circ Res"},{"key":"R62","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1093\/sleep\/22.8.1067","article-title":"Heart rate variability during waking and sleep in healthy males and females","volume":"22","author":"Elsenbruch","year":"1999","journal-title":"Sleep"},{"key":"R63","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1097\/01.psy.0000146793.90058.c3","article-title":"Autonomic nervous system assessment throughout the wake-sleep cycle and stress","volume":"66","author":"Lechin","year":"2004","journal-title":"Psychosom Med"},{"key":"R64","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1037\/1089-2680.10.3.229","article-title":"Heart Rate Variability as an Index of Regulated Emotional Responding","volume":"10","author":"Appelhans","year":"2006","journal-title":"Rev Gen Psychol"},{"key":"R65","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.neubiorev.2008.08.004","article-title":"Claude Bernard and the heart\u2013brain connection: Further elaboration of a model of neurovisceral integration","volume":"33","author":"Thayer","year":"2009","journal-title":"Neurosci Biobehav Rev"},{"key":"R66","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1586\/14737175.7.1.63","article-title":"Vagus nerve stimulation for the treatment of depression and other neuropsychiatric disorders","volume":"7","author":"George","year":"2007","journal-title":"Expert Rev Neurother"},{"key":"R67","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1038\/sj.npp.1301082","article-title":"VNS therapy in treatment-resistant depression: clinical evidence and putative neurobiological mechanisms","volume":"31","author":"Nemeroff","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"R68","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.neuroimage.2008.07.056","article-title":"Neural correlates of heart rate variability during emotion","volume":"44","author":"Lane","year":"2009","journal-title":"Neuroimage"},{"key":"R69","doi-asserted-by":"crossref","first-page":"586","DOI":"10.3109\/15622970903397714","article-title":"Altered cardiovascular adaptability in depressed patients without heart disease","volume":"11","author":"Ehrenthal","year":"2010","journal-title":"World J Biol Psychiatry"},{"key":"R70","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1176\/appi.psy.45.2.129","article-title":"Heart rate variability in patients with major depression","volume":"45","author":"Nahshoni","year":"2004","journal-title":"Psychosomatics"},{"key":"R71","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0031-9384(03)00156-2","article-title":"The Polyvagal Theory: phylogenetic contributions to social behavior","volume":"79","author":"Porges","year":"2003","journal-title":"Physiol Behav"},{"key":"R72","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.biopsycho.2006.06.009","article-title":"The polyvagal perspective","volume":"74","author":"Porges","year":"2007","journal-title":"Biol Psychol"},{"key":"R73","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.neuroimage.2009.05.010","article-title":"Visceral brain\u2013body information transfer","volume":"47","author":"Cameron","year":"2009","journal-title":"Neuroimage"},{"key":"R74","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1109\/MEMB.2002.1032635","article-title":"Neurovisceral integration in cardiac and emotional regulation","volume":"21","author":"Thayer","year":"2002","journal-title":"IEEE Eng Med Biol Mag"},{"key":"R75","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.biopsych.2009.12.012","article-title":"Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis","volume":"67","author":"Kemp","year":"2010","journal-title":"Biol Psychiatry"},{"key":"R76","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.smrv.2005.06.001","article-title":"Nightmares: from anxiety symptom to sleep disorder","volume":"10","author":"Spoormaker","year":"2006","journal-title":"Sleep Med Rev"},{"key":"R77","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1176\/appi.ajp.159.5.855","article-title":"Sleep complaints as early predictors of posttraumatic stress disorder: a 1-year prospective study of injured survivors of motor vehicle accidents","volume":"159","author":"Koren","year":"2002","journal-title":"Am J Psychiatry"},{"key":"R78","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1176\/appi.ajp.159.10.1696","article-title":"REM sleep and the early development of posttraumatic stress disorder","volume":"159","author":"Mellman","year":"2002","journal-title":"Am J Psychiatry"},{"key":"R79","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1017\/S1092852900013663","article-title":"Sleep disturbances in the aftermath of trauma and posttraumatic stress disorder","volume":"11","author":"Mellman","year":"2006","journal-title":"CNS Spectr"},{"key":"R80","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1023\/A:1025750209553","article-title":"Acute psychophysiological arousal and posttraumatic stress disorder: a two-year prospective study","volume":"16","author":"Bryant","year":"2003","journal-title":"J Trauma Stress"},{"key":"R81","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/01.PSY.0000106884.58744.09","article-title":"Acute stress affects heart rate variability during sleep","volume":"66","author":"Hall","year":"2004","journal-title":"Psychosom Med"},{"key":"R82","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jpsychires.2005.08.002","article-title":"Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review","volume":"40","author":"de Kloet","year":"2006","journal-title":"J Psychiatr Res"},{"key":"R83","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1192\/bjp.bp.106.024877","article-title":"Cortisol and post-traumatic stress disorder in adults: systematic review and meta-analysis","volume":"191","author":"Meewisse","year":"2007","journal-title":"Br J Psychiatry"},{"key":"R84","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1002\/jclp.20730","article-title":"Treatment of nightmares in the context of posttraumatic stress disorder","volume":"66","author":"Gehrman","year":"2010","journal-title":"J Clin Psychol"},{"key":"R85","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1038\/ki.1996.220","article-title":"Evolutionary aspects of renal function","volume":"49","author":"Natochin","year":"1996","journal-title":"Kidney Int"},{"key":"R86","unstructured":"Felig P, Baxter JD, Brodaus AB, Frohman LA. Endocrinology and Metabolism, in McGraw ed, Hill NY, 1987."},{"key":"R87","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/S1357-2725(03)00139-0","article-title":"The syndrome of inappropriate antidiuretic hormone secretion","volume":"35","author":"Baylis","year":"2003","journal-title":"Int J Biochem Cell Biol"},{"key":"R88","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/nn.2503","article-title":"Central clock excites vasopressin neurons by waking osmosensory afferents during late sleep","volume":"13","author":"Trudel","year":"2010","journal-title":"Nat Neurosci"},{"key":"R89","doi-asserted-by":"crossref","first-page":"16523","DOI":"10.1073\/pnas.0904890106","article-title":"Molecular clock is involved in predictive circadian adjustment of renal function","volume":"106","author":"Zuber","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"R90","doi-asserted-by":"crossref","first-page":"F404","DOI":"10.1152\/ajprenal.00126.2010","article-title":"Excess diuresis and natriuresis during acute sleep deprivation in healthy adults","volume":"299","author":"Kamperis","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"key":"R91","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2174\/138920306775474086","article-title":"On the existence of a global molecular network enmeshing the whole central nervous system: physiological and pathological implications","volume":"7","author":"Agnati","year":"2006","journal-title":"Curr Protein Pept Sci"},{"key":"R92","first-page":"T114","article-title":"Brain Plasticity, Signal Transduction and Epigenesis: a Missing Link Revealed","volume":"11","author":"B\u00e1ez-Saldana","year":"2009","journal-title":"Ann Rev Biomed Scie"},{"key":"R93","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1748-1716.2006.01579.x","article-title":"Volume transmission and wiring transmission from cellular to molecular networks: history and perspectives","volume":"187","author":"Agnati","year":"2006","journal-title":"Acta Physiol (Oxf)"},{"key":"R94","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.brainresrev.2007.03.004","article-title":"One century of progress in neuroscience founded on Golgi and Cajal's outstanding experimental and theoretical contributions","volume":"55","author":"Agnati","year":"2007","journal-title":"Brain Res Brain Res Rev"},{"key":"R95","unstructured":"Jacob F. La logique du vivant. Une histoire de l'h\u00e9r\u00e9dit\u00e9. In: Gallimard Ed, Paris, 1970."},{"key":"R96","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF01120304","article-title":"New concepts on the structure of the neuronal networks: the miniaturization and hierarchical organization of the central nervous system. (Hypothesis)","volume":"4","author":"Agnati","year":"1984","journal-title":"Biosci Rep"},{"key":"R97","unstructured":"Agnati LF. Neuroscienze e filosofia: antiche e nuove \u201cmitologie\u201d. Hermeneutica 2008; 269-299."},{"key":"R98","first-page":"183","article-title":"New vistas on synaptic plasticity: mosaic hypothesis on the engram","volume":"60","author":"Agnati","year":"1982","journal-title":"Med Biol"},{"key":"R99","unstructured":"Agnati LF, Benfenati F, Ferri M, Morpurgo A, Apolloni B, Fuxe K. Molecular basis of learning and memory: modeling based on receptor mosaics. In: Apolloni B, Kurfess F eds. From synapses to rules: discovering symbolic rules from neural processed data. Kluwer Academic\/Plenum Press Publisher, New York, 1988: 165-196."},{"key":"R100","first-page":"195","article-title":"Possible role of intramembrane receptor-receptor interactions in memory and learning via formation of long-lived heteromeric complexes: focus on motor learning in the basal ganglia","volume":"65","author":"Agnati","year":"2003","journal-title":"J Neural Transm"},{"key":"R101","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.brainresrev.2007.02.004","article-title":"On the role of receptor-receptor interactions and volume transmission in learning and memory","volume":"55","author":"Guidolin","year":"2007","journal-title":"Brain Res Brain Res Rev"},{"key":"R102","first-page":"T114","article-title":"Brain Plasticity, Signal Transduction and Epigenesis: a Missing Link Revealed","volume":"11","author":"B\u00e1ez-Saldana","year":"2009","journal-title":"Ann Rev Biomed Sci"},{"key":"R103","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1038\/nn0804-791","article-title":"Mothering style and methylation","volume":"7","author":"Sapolsky","year":"2004","journal-title":"Nat Neurosci"},{"key":"R104","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/nature05913","article-title":"Perceptions of epigenetics","volume":"447","author":"Bird","year":"2007","journal-title":"Nature"},{"key":"R105","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.neubiorev.2007.10.009","article-title":"Epigenetic mechanisms mediating the long-term effects of maternal care on development","volume":"33","author":"Champagne","year":"2009","journal-title":"Neurosci Biobehav Rev"},{"key":"R106","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.biopsych.2008.11.028","article-title":"Lasting epigenetic influence of early-life adversity on the BDNF gene","volume":"65","author":"Roth","year":"2009","journal-title":"Biol Psychiatry"},{"key":"R107","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/sleep\/30.2.129","article-title":"Exploratory behaviour, cortical BDNF expression, and sleep homeostasis","volume":"30","author":"Huber","year":"2007","journal-title":"Sleep"},{"key":"R108","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.tics.2007.09.001","article-title":"The contribution of sleep to hippocampus-dependent memory consolidation","volume":"11","author":"Marshall","year":"2007","journal-title":"Trends Cogn Sci"},{"key":"R109","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1371\/journal.pbio.0020024","article-title":"Long lasting novelty-induced neuronal reverberation during slow-wave sleep in multiple forebrain areas","volume":"2","author":"Ribeiro","year":"2004","journal-title":"PLoS Biol"},{"key":"R110","doi-asserted-by":"crossref","first-page":"6731","DOI":"10.1523\/JNEUROSCI.1227-08.2008","article-title":"Theta and gamma coordination of hippocampal networks during waking and rapid eye movement sleep","volume":"28","author":"Montgomery","year":"2008","journal-title":"J Neurosci"},{"key":"R111","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/cercor\/6.2.81","article-title":"The hippocampo-neocortical dialogue","volume":"6","author":"Buzs\u00e1ki","year":"1996","journal-title":"Cereb Cortex"},{"key":"R112","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1046\/j.1365-2869.7.s1.3.x","article-title":"Memory consolidation during sleep: a neurophysiological perspective","volume":"7","author":"Buzs\u00e1ki","year":"1998","journal-title":"J Sleep Res"},{"key":"R113","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1073\/pnas.0400237101","article-title":"Slow-wave sleep, acetylcholine, and memory consolidation","volume":"101","author":"Power","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"R114","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2174\/1874467211003010012","article-title":"Brain-derived neurotrophic factor: a dynamic gatekeeper of neural plasticity","volume":"3","author":"Cowansage","year":"2010","journal-title":"Curr Mol Pharmacol"},{"key":"R115","doi-asserted-by":"crossref","first-page":"4796","DOI":"10.1523\/JNEUROSCI.5654-03.2004","article-title":"Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning","volume":"24","author":"Rattiner","year":"2004","journal-title":"J Neurosci"},{"key":"R116","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1038\/nn1718","article-title":"Amygdala BDNF signaling is required for consolidation but not encoding of extinction","volume":"9","author":"Chhatwal","year":"2006","journal-title":"Nat Neurosci"},{"key":"R117","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/sj.npp.1300830","article-title":"Regulation of amygdala-dependent learning by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol-3-kinase","volume":"31","author":"Ou","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"R118","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nature01138","article-title":"Neurons in medial prefrontal cortex signal memory for fear extinction","volume":"420","author":"Milad","year":"2002","journal-title":"Nature"},{"key":"R119","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1037\/0735-7044.118.2.389","article-title":"Electrical stimulation of medial prefrontal cortex reduces conditioned fear in a temporally specific manner","volume":"118","author":"Milad","year":"2004","journal-title":"Behav Neurosci"},{"key":"R120","doi-asserted-by":"crossref","first-page":"5704","DOI":"10.1523\/JNEUROSCI.0786-04.2004","article-title":"Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex","volume":"24","author":"Santini","year":"2004","journal-title":"J Neurosci"},{"key":"R121","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.1073\/pnas.0909359107","article-title":"Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear","volume":"107","author":"Choi","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"R122","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1017\/S0140525X00003976","article-title":"Dreaming and the brain: toward a cognitive neuroscience of conscious states","volume":"23","author":"Hobson","year":"2000","journal-title":"Behav Brain Sci"},{"key":"R123","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.smrv.2007.03.004","article-title":"Nightmares: a new neurocognitive model","volume":"11","author":"Nielsen","year":"2007","journal-title":"Sleep Med Rev"},{"key":"R124","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.smrv.2005.06.001","article-title":"Nightmares: from anxiety symptom to sleep disorder","volume":"10","author":"Spoormaker","year":"2006","journal-title":"Sleep Med Rev"},{"key":"R125","doi-asserted-by":"crossref","unstructured":"Bernard C. Le\u00e7ons sur les ph\u00e9nom\u00e8nes de la vie communs aux animaux et aux v\u00e9g\u00e9taux. In: Albert Dastre, eds. Bailli\u00e8re et fils, Paris, 1878-1879.","DOI":"10.5962\/bhl.title.103133"},{"key":"R126","unstructured":"Cannon WE. A discussion of the regulation of body fluids, hunger, thirst, temperature, oxygen supply, water, sugar, and proteins of the body, and the role of the asympathetic-adrenal mechanism. In: Cannon eds. The wisdom of the body. Norton & Co, New York, 1932."},{"key":"R127","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0026-0495(03)00295-6","article-title":"Interacting mediators of allostasis and allostatic load: towards an understanding of resilience in aging","volume":"52","author":"McEwen","year":"2003","journal-title":"Metabolism"},{"key":"R128","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.parkreldis.2004.03.005","article-title":"Striatal plasticity and motor learning-importance of circadian rhythms, sleep stages and dreaming","volume":"10","author":"Horowski","year":"2004","journal-title":"Parkinsonism Relat Disord"},{"key":"R129","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0074-7742(10)92002-3","article-title":"Dreaming as inspiration evidence from religion, philosophy, literature, and film","volume":"92","author":"Bulkeley","year":"2010","journal-title":"Int Rev Neurobiol"},{"key":"R130","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1037\/h0025238","article-title":"Essentials of implosive therapy: A learning-theory-based psychodynamic behavioral therapy","volume":"72","author":"Stampfl","year":"1967","journal-title":"J Abnorm Psychol"},{"key":"R131","doi-asserted-by":"crossref","first-page":"487","DOI":"10.5664\/jcsm.27940","article-title":"Nightmare reduction in a Vietnam veteran using imagery rehearsal therapy","volume":"6","author":"Berlin","year":"2010","journal-title":"J Clin Sleep Med"},{"key":"R132","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1017\/S0140525X00004015","article-title":"The reinterpretation of dreams: an evolutionary hypothesis of the function of dreaming","volume":"23","author":"Revonsuo","year":"2000","journal-title":"Behav Brain Sci"},{"key":"R133","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1037\/1053-0797.17.2.113","article-title":"Representation of the Self in REM and NREM Dreams","volume":"17","author":"McNamara","year":"2007","journal-title":"Dreaming"},{"key":"R134","doi-asserted-by":"crossref","first-page":"604","DOI":"10.2741\/3636","article-title":"The interrelationship between sleep regulation and thermoregulation","volume":"15","author":"Krauchi","year":"2010","journal-title":"Front Biosci"},{"key":"R135","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1093\/sleep\/10.5.426","article-title":"Interaction between sleep and thermoregulation: an aspect of the control of behavioral states","volume":"10","author":"Parmeggiani","year":"1987","journal-title":"Sleep"},{"key":"R136","doi-asserted-by":"crossref","DOI":"10.1016\/j.conb.2011.06.008","article-title":"When brain clocks lose track of time: cause or consequence of neuropsychiatric disorders","author":"Menet","year":"2011","journal-title":"Curr Opin Neurobiol"},{"key":"R137","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1152\/jn.1998.80.3.1480","article-title":"Spike-wave complexes and fast components of cortically generated seizures. III. Synchronizing mechanisms","volume":"80","author":"Neckelmann","year":"1998","journal-title":"J Neurophysiol"}],"container-title":["Communicative & Integrative Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.4161\/cib.17602","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,22]],"date-time":"2020-08-22T10:37:58Z","timestamp":1598092678000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/abs\/10.4161\/cib.17602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":137,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2014,10,28]]},"published-print":{"date-parts":[[2011,11]]}},"alternative-id":["10.4161\/cib.17602"],"URL":"https:\/\/doi.org\/10.4161\/cib.17602","relation":{},"ISSN":["1942-0889"],"issn-type":[{"value":"1942-0889","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11]]}}}