{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:09:16Z","timestamp":1791425356306,"version":"4.3.3"},"reference-count":38,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epigenetics"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.4161\/epi.20237","type":"journal-article","created":{"date-parts":[[2012,6,22]],"date-time":"2012-06-22T21:27:04Z","timestamp":1340400424000},"page":"567-578","source":"Crossref","is-referenced-by-count":91,"title":["Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia"],"prefix":"10.1080","volume":"7","author":[{"given":"Lirong","family":"Pei","sequence":"first","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"},{"name":"Department of Biochemistry and Molecular Biology; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Hyeon","family":"Choi","sequence":"additional","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"},{"name":"Department of Biostatistics; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimei","family":"Liu","sequence":"additional","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"},{"name":"Department of Biochemistry and Molecular Biology; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Joon","family":"Lee","sequence":"additional","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"},{"name":"Department of Biochemistry and Molecular Biology; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"McCarthy","sequence":"additional","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M.","family":"Wilson","sequence":"additional","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"},{"name":"Department of Biochemistry and Molecular Biology; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ethan","family":"Speir","sequence":"additional","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"},{"name":"Department of Biochemistry and Molecular Biology; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farrukh","family":"Awan","sequence":"additional","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongseok","family":"Tae","sequence":"additional","affiliation":[{"name":"The Center for Genomics and Bioinformatics; Indiana University; Bloomington, IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Arthur","sequence":"additional","affiliation":[{"name":"Department of Pathology and Anatomical Sciences; University of Missouri; Columbia, MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L.","family":"Schnabel","sequence":"additional","affiliation":[{"name":"Department of Pathology and Anatomical Sciences; University of Missouri; Columbia, MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen H.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Pathology and Anatomical Sciences; University of Missouri; Columbia, MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinguo","family":"Wang","sequence":"additional","affiliation":[{"name":"David H. Murdock Research Institute; Kannapolis, NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Computer Science; Christopher S. Bond Life Sciences Center and Informatics Institute; University of Missouri; Columbia, MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Fei","family":"Ding","sequence":"additional","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H.","family":"Munn","sequence":"additional","affiliation":[{"name":"Immunotherapy Center; Georgia Health Sciences University; Augusta, GA USA"},{"name":"Department of Pediatrics; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Caldwell","sequence":"additional","affiliation":[{"name":"Department of Pathology and Anatomical Sciences; University of Missouri; Columbia, MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huidong","family":"Shi","sequence":"additional","affiliation":[{"name":"GHSU Cancer Center; Georgia Health Sciences University; Augusta, GA USA"},{"name":"Department of Biochemistry and Molecular Biology; Georgia Health Sciences University; Augusta, GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2012,6]]},"reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2009.1.421"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-08-207126"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2010.03.004"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.15.4393"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-07-155663"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra072067"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.03.043"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-3712"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-05-284638"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1080\/10428190902756594"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2009.10.018"},{"key":"R12","first-page":"1078","volume":"90","author":"Corcoran M","year":"2005","journal-title":"Haematologica"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.02.196"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0906455106"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-03-2870"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-07-232868"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.2217\/epi.09.10"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.4161\/epi.5.6.12179"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404254"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1038\/nature07107"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000533"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.4161\/epi.9137"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0006986"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2008.060152"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-06-357996"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0308648100"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-02-269878"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M808048200"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-12-257485"},{"key":"R30","doi-asserted-by":"publisher","DOI":"10.1038\/nature08750"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-09-242438"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-12-257378"},{"key":"R33","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-03-1167"},{"key":"R34","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20100945"},{"key":"R35","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-09-111344"},{"key":"R36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05313.x"},{"key":"R37","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1414"},{"key":"R38","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","volume":"57","author":"Benjamini Y","year":"1995","journal-title":"J Roy Stat Soc B Met"}],"container-title":["Epigenetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.4161\/epi.20237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:39:05Z","timestamp":1714091945000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.4161\/epi.20237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":38,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2012,6]]},"published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.4161\/epi.20237"],"URL":"https:\/\/doi.org\/10.4161\/epi.20237","relation":{},"ISSN":["1559-2294","1559-2308"],"issn-type":[{"value":"1559-2294","type":"print"},{"value":"1559-2308","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}