{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:02:30Z","timestamp":1780318950069,"version":"3.54.1"},"reference-count":42,"publisher":"XMLink","issue":"4","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003052","name":"Ministry of Trade, Industry and Energy","doi-asserted-by":"publisher","award":["R0005131"],"award-info":[{"award-number":["R0005131"]}],"id":[{"id":"10.13039\/501100003052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003661","name":"Korea Institute for Advancement of Technology","doi-asserted-by":"publisher","award":["R0005131"],"award-info":[{"award-number":["R0005131"]}],"id":[{"id":"10.13039\/501100003661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002632","name":"Hallym University","doi-asserted-by":"publisher","award":["B0008864"],"award-info":[{"award-number":["B0008864"]}],"id":[{"id":"10.13039\/501100002632","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Nutr Res Pract"],"published-print":{"date-parts":[[2018]]},"DOI":"10.4162\/nrp.2018.12.4.275","type":"journal-article","created":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T08:03:36Z","timestamp":1533197016000},"page":"275","update-policy":"https:\/\/doi.org\/10.4162\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Effect of isoflavone-enriched whole soy milk powder supplementation on bone metabolism in ovariectomized mice"],"prefix":"10.4162","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0174-3485","authenticated-orcid":false,"given":"So Mi","family":"Kim","sequence":"first","affiliation":[{"name":"Center for Efficacy Assessment and Development of Functional Foods and Drugs, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon 24252, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8642-1978","authenticated-orcid":false,"given":"Hyun Sook","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Food Science & Nutrition, Dongseo University, Busan 47011, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4475-1434","authenticated-orcid":false,"given":"Jae In","family":"Jung","sequence":"additional","affiliation":[{"name":"Center for Efficacy Assessment and Development of Functional Foods and Drugs, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon 24252, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3345-8128","authenticated-orcid":false,"given":"Su-Min","family":"Lim","sequence":"additional","affiliation":[{"name":"Center for Efficacy Assessment and Development of Functional Foods and Drugs, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon 24252, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4147-8329","authenticated-orcid":false,"given":"Ji Hoon","family":"Lim","sequence":"additional","affiliation":[{"name":"Institute of Food Processing Technology, Uwell Bio Co. Ltd., Gangwon 25451, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3941-9744","authenticated-orcid":false,"given":"Wang-Hyun","family":"Ha","sequence":"additional","affiliation":[{"name":"Institute of Food Processing Technology, Uwell Bio Co. Ltd., Gangwon 25451, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6682-362X","authenticated-orcid":false,"given":"Chang Lae","family":"Jeon","sequence":"additional","affiliation":[{"name":"Institute of Food Processing Technology, Uwell Bio Co. Ltd., Gangwon 25451, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9820-1235","authenticated-orcid":false,"given":"Jae-Yong","family":"Lee","sequence":"additional","affiliation":[{"name":"Center for Efficacy Assessment and Development of Functional Foods and Drugs, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon 24252, Korea."},{"name":"Department of Biochemistry, College of Medicine, Hallym University, Gangwon 24252, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9305-4769","authenticated-orcid":false,"given":"Eun Ji","family":"Kim","sequence":"additional","affiliation":[{"name":"Center for Efficacy Assessment and Development of Functional Foods and Drugs, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon 24252, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.4162\/nrp.2018.12.4.275_ref1","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1517\/14656566.2011.618123","volume":"12","author":"Lecart","year":"2011","journal-title":"Expert Opin Pharmacother"},{"key":"10.4162\/nrp.2018.12.4.275_ref2","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s40520-016-0599-1","volume":"29","author":"Seckin","year":"2017","journal-title":"Aging Clin Exp Res"},{"key":"10.4162\/nrp.2018.12.4.275_ref3","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/jama.288.3.321","volume":"288","author":"Rossouw","year":"2002","journal-title":"JAMA"},{"key":"10.4162\/nrp.2018.12.4.275_ref4","first-page":"213","volume":"13","author":"Gambacciani","year":"2014","journal-title":"Prz Menopauzalny"},{"key":"10.4162\/nrp.2018.12.4.275_ref5","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s12011-016-0882-1","volume":"177","author":"Qi","year":"2017","journal-title":"Biol Trace Elem Res"},{"key":"10.4162\/nrp.2018.12.4.275_ref6","doi-asserted-by":"crossref","first-page":"651","DOI":"10.33549\/physiolres.931902","volume":"59","author":"Pil\u0161\u00e1kov\u00e1","year":"2010","journal-title":"Physiol Res"},{"key":"10.4162\/nrp.2018.12.4.275_ref7","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s13318-012-0112-y","volume":"38","author":"Vitale","year":"2013","journal-title":"Eur J Drug Metab Pharmacokinet"},{"key":"10.4162\/nrp.2018.12.4.275_ref8","first-page":"173","volume":"6","author":"Moutsatsou","year":"2007","journal-title":"Hormones (Athens)"},{"key":"10.4162\/nrp.2018.12.4.275_ref9","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1055\/s-2003-41122","volume":"69","author":"Cos","year":"2003","journal-title":"Planta Med"},{"key":"10.4162\/nrp.2018.12.4.275_ref10","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.jnutbio.2006.01.003","volume":"17","author":"Huang","year":"2006","journal-title":"J Nutr Biochem"},{"key":"10.4162\/nrp.2018.12.4.275_ref11","doi-asserted-by":"crossref","first-page":"5217","DOI":"10.1210\/jcem.86.11.8040","volume":"86","author":"Mei","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4162\/nrp.2018.12.4.275_ref12","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1001\/archinte.165.16.1890","volume":"165","author":"Zhang","year":"2005","journal-title":"Arch Intern Med"},{"key":"10.4162\/nrp.2018.12.4.275_ref13","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1089\/jmf.2005.8.439","volume":"8","author":"Kim","year":"2005","journal-title":"J Med Food"},{"key":"10.4162\/nrp.2018.12.4.275_ref14","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1038\/bjp.2008.305","volume":"155","author":"Bitto","year":"2008","journal-title":"Br J Pharmacol"},{"key":"10.4162\/nrp.2018.12.4.275_ref15","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1001\/jama.295.17.2057","volume":"295","author":"Nelson","year":"2006","journal-title":"JAMA"},{"key":"10.4162\/nrp.2018.12.4.275_ref16","doi-asserted-by":"crossref","first-page":"3318","DOI":"10.1172\/JCI27071","volume":"115","author":"Raisz","year":"2005","journal-title":"J Clin Invest"},{"key":"10.4162\/nrp.2018.12.4.275_ref17","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1210\/en.2003-0319","volume":"145","author":"Bergh","year":"2004","journal-title":"Endocrinology"},{"key":"10.4162\/nrp.2018.12.4.275_ref18","first-page":"671","volume":"29","author":"Klepzig","year":"2009","journal-title":"Anticancer Res"},{"key":"10.4162\/nrp.2018.12.4.275_ref19","doi-asserted-by":"crossref","first-page":"28370","DOI":"10.1074\/jbc.M502469200","volume":"280","author":"Ljusberg","year":"2005","journal-title":"J Biol Chem"},{"key":"10.4162\/nrp.2018.12.4.275_ref20","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1097\/00075197-200111000-00009","volume":"4","author":"Campbell","year":"2001","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.4162\/nrp.2018.12.4.275_ref21","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.maturitas.2004.08.013","volume":"51","author":"Misso","year":"2005","journal-title":"Maturitas"},{"key":"10.4162\/nrp.2018.12.4.275_ref22","doi-asserted-by":"crossref","first-page":"375102","DOI":"10.1088\/0957-4484\/20\/37\/375102","volume":"20","author":"Huang","year":"2009","journal-title":"Nanotechnology"},{"key":"10.4162\/nrp.2018.12.4.275_ref23","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jsbmb.2010.03.029","volume":"122","author":"Zoth","year":"2010","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.4162\/nrp.2018.12.4.275_ref24","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jsbmb.2017.11.002","volume":"178","author":"Zheng","year":"2018","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.4162\/nrp.2018.12.4.275_ref25","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.metabol.2004.01.019","volume":"53","author":"Wu","year":"2004","journal-title":"Metabolism"},{"key":"10.4162\/nrp.2018.12.4.275_ref26","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/j.bone.2007.02.006","volume":"40","author":"Hertrampf","year":"2007","journal-title":"Bone"},{"key":"10.4162\/nrp.2018.12.4.275_ref27","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/archinternmed.2011.330","volume":"171","author":"Levis","year":"2011","journal-title":"Arch Intern Med"},{"key":"10.4162\/nrp.2018.12.4.275_ref28","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1021\/jf00044a016","volume":"42","author":"Wang","year":"1994","journal-title":"J Agric Food Chem"},{"key":"10.4162\/nrp.2018.12.4.275_ref29","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00223001100","volume":"67","author":"Davey","year":"2000","journal-title":"Calcif Tissue Int"},{"key":"10.4162\/nrp.2018.12.4.275_ref30","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00774-004-0547-6","volume":"23","author":"Nishizawa","year":"2005","journal-title":"J Bone Miner Metab"},{"key":"10.4162\/nrp.2018.12.4.275_ref31","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.bone.2010.05.001","volume":"47","author":"Taku","year":"2010","journal-title":"Bone"},{"key":"10.4162\/nrp.2018.12.4.275_ref32","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.nutres.2014.05.003","volume":"34","author":"Fu","year":"2014","journal-title":"Nutr Res"},{"key":"10.4162\/nrp.2018.12.4.275_ref33","first-page":"97","volume":"26","author":"Seibel","year":"2005","journal-title":"Clin Biochem Rev"},{"key":"10.4162\/nrp.2018.12.4.275_ref34","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1080\/10408360801949442","volume":"45","author":"Vasikaran","year":"2008","journal-title":"Crit Rev Clin Lab Sci"},{"key":"10.4162\/nrp.2018.12.4.275_ref35","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1185\/030079905X41390","volume":"21","author":"Miller","year":"2005","journal-title":"Curr Med Res Opin"},{"key":"10.4162\/nrp.2018.12.4.275_ref36","doi-asserted-by":"crossref","first-page":"5050","DOI":"10.1210\/endo.142.12.8536","volume":"142","author":"Khosla","year":"2001","journal-title":"Endocrinology"},{"key":"10.4162\/nrp.2018.12.4.275_ref37","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/S1359-6446(02)02260-2","volume":"7","author":"Bateman","year":"2002","journal-title":"Drug Discov Today"},{"key":"10.4162\/nrp.2018.12.4.275_ref38","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1093\/ajcn\/87.3.761","volume":"87","author":"Brink","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"10.4162\/nrp.2018.12.4.275_ref39","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s00394-004-0497-8","volume":"43","author":"Lydeking-Olsen","year":"2004","journal-title":"Eur J Nutr"},{"key":"10.4162\/nrp.2018.12.4.275_ref40","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1210\/jc.2003-031166","volume":"89","author":"Nikander","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.4162\/nrp.2018.12.4.275_ref41","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1359\/jbmr.2000.15.7.1337","volume":"15","author":"Halleen","year":"2000","journal-title":"J Bone Miner Res"},{"key":"10.4162\/nrp.2018.12.4.275_ref42","first-page":"1027","volume":"23","author":"Halleen","year":"2003","journal-title":"Anticancer Res"}],"container-title":["Nutrition Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.4162\/nrp.2018.12.4.275","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4162\/nrp.2018.12.4.275","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-nrp.org\/DOIx.php?id=10.4162\/nrp.2018.12.4.275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T17:07:36Z","timestamp":1661706456000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-nrp.org\/DOIx.php?id=10.4162\/nrp.2018.12.4.275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.4162\/nrp.2018.12.4.275","relation":{},"ISSN":["1976-1457","2005-6168"],"issn-type":[{"value":"1976-1457","type":"print"},{"value":"2005-6168","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4162\/nrp.2018.12.4.275","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4162\/nrp.2018.12.4.275","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"https:\/\/e-nrp.org\/DOIx.php?id=10.4162\/nrp.2018.12.4.275","URL":"https:\/\/e-nrp.org\/DOIx.php?id=10.4162\/nrp.2018.12.4.275","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2018-02-14","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-03","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-15","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a92018 The Korean Nutrition Society and the Korean Society of Community Nutrition","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}