{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:07:28Z","timestamp":1793138848966,"version":"4.5.0"},"reference-count":84,"publisher":"The Korean Society of Gastroenterology","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Korean J Gastroenterol"],"published-print":{"date-parts":[[2017]]},"DOI":"10.4166\/kjg.2017.70.1.4","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T04:42:07Z","timestamp":1502426527000},"page":"4","source":"Crossref","is-referenced-by-count":31,"title":["The Effect of H<sub>2<\/sub>Receptor Antagonist in Acid Inhibition and Its Clinical Efficacy"],"prefix":"10.4166","volume":"70","author":[{"given":"Young Kwang","family":"Shim","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayoung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Korea."},{"name":"Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2668","reference":[{"key":"10.4166\/kjg.2017.70.1.4_ref1","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0950-3528(88)80007-1","volume":"2","author":"Pounder","year":"1988","journal-title":"Baillieres Clin Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref2","doi-asserted-by":"crossref","first-page":"300","DOI":"10.4166\/kjg.2016.67.6.300","volume":"67","author":"Shim","year":"2016","journal-title":"Korean J Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref3","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1159\/000199610","volume":"39","author":"Brunner","year":"1988","journal-title":"Digestion"},{"key":"10.4166\/kjg.2017.70.1.4_ref4","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1136\/gut.31.6.653","volume":"31","year":"1990","journal-title":"Gut"},{"issue":"3A","key":"10.4166\/kjg.2017.70.1.4_ref5","doi-asserted-by":"crossref","first-page":"56S","DOI":"10.1016\/S0002-9343(97)00213-1","volume":"104","author":"Yeomans","year":"1998","journal-title":"Am J Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref6","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1056\/NEJM199903183401101","volume":"340","author":"Lagergren","year":"1999","journal-title":"N Engl J Med"},{"issue":"Suppl 2","key":"10.4166\/kjg.2017.70.1.4_ref7","first-page":"S6","volume":"13","author":"Katz","year":"1991","journal-title":"J Clin Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref8","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1001\/archinte.159.18.2161","volume":"159","author":"Fass","year":"1999","journal-title":"Arch Intern Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref9","first-page":"1881","volume":"58","author":"Habu","year":"2000","journal-title":"Nihon Rinsho"},{"key":"10.4166\/kjg.2017.70.1.4_ref10","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/BF01296445","volume":"31","author":"Delchier","year":"1986","journal-title":"Dig Dis Sci"},{"key":"10.4166\/kjg.2017.70.1.4_ref11","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1056\/NEJM198403223101205","volume":"310","author":"Lamers","year":"1984","journal-title":"N Engl J Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref12","first-page":"717","volume":"89","author":"Ducrott\u00e9","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref13","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1136\/gut.31.9.968","volume":"31","author":"Bate","year":"1990","journal-title":"Gut"},{"key":"10.4166\/kjg.2017.70.1.4_ref14","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1002\/hep.28737","volume":"64","author":"Dam","year":"2016","journal-title":"Hepatology"},{"key":"10.4166\/kjg.2017.70.1.4_ref15","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1053\/j.gastro.2017.01.031","volume":"152","author":"Freedberg","year":"2017","journal-title":"Gastroenterology"},{"key":"10.4166\/kjg.2017.70.1.4_ref16","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1517\/13543776.2013.741121","volume":"23","author":"Li","year":"2013","journal-title":"Expert Opin Ther Pat"},{"key":"10.4166\/kjg.2017.70.1.4_ref17","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.pharmthera.2005.05.005","volume":"108","author":"Andersson","year":"2005","journal-title":"Pharmacol Ther"},{"key":"10.4166\/kjg.2017.70.1.4_ref18","first-page":"1255","volume":"103","author":"Hallenbeck","year":"1970","journal-title":"Can Med Assoc J"},{"key":"10.4166\/kjg.2017.70.1.4_ref19","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1136\/bmj.1.3607.348","volume":"1","author":"Luff","year":"1930","journal-title":"Br Med J"},{"key":"10.4166\/kjg.2017.70.1.4_ref20","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1136\/gut.8.2.151","volume":"8","author":"Kemp","year":"1967","journal-title":"Gut"},{"key":"10.4166\/kjg.2017.70.1.4_ref21","first-page":"1018","volume":"125","author":"Whittaker","year":"1967","journal-title":"Surg Gynecol Obstet"},{"key":"10.4166\/kjg.2017.70.1.4_ref22","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3109\/00365521.2011.639083","volume":"47","author":"Kang","year":"2012","journal-title":"Scand J Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref23","doi-asserted-by":"crossref","first-page":"7690","DOI":"10.1016\/S0021-9258(17)32907-1","volume":"251","author":"Sachs","year":"1976","journal-title":"J Biol Chem"},{"key":"10.4166\/kjg.2017.70.1.4_ref24","doi-asserted-by":"crossref","first-page":"25","DOI":"10.5056\/jnm.2013.19.1.25","volume":"19","author":"Shin","year":"2013","journal-title":"J Neurogastroenterol Motil"},{"key":"10.4166\/kjg.2017.70.1.4_ref25","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/236385a0","volume":"236","author":"Black","year":"1972","journal-title":"Nature"},{"key":"10.4166\/kjg.2017.70.1.4_ref26","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/BF01078346","volume":"22","author":"Okabe","year":"1977","journal-title":"Am J Dig Dis"},{"key":"10.4166\/kjg.2017.70.1.4_ref27","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0140-6736(77)92055-4","volume":"1","author":"Macdougall","year":"1977","journal-title":"Lancet"},{"key":"10.4166\/kjg.2017.70.1.4_ref28","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1136\/bmj.1.6110.398","volume":"1","author":"Jones","year":"1978","journal-title":"Br Med J"},{"key":"10.4166\/kjg.2017.70.1.4_ref29","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1016\/0140-6736(92)92023-9","volume":"339","author":"Bossi","year":"1992","journal-title":"Lancet"},{"key":"10.4166\/kjg.2017.70.1.4_ref30","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4168\/aair.2011.3.2.128","volume":"3","author":"Song","year":"2011","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4166\/kjg.2017.70.1.4_ref31","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0163-7258(03)00015-9","volume":"98","author":"Aihara","year":"2003","journal-title":"Pharmacol Ther"},{"key":"10.4166\/kjg.2017.70.1.4_ref32","first-page":"271","volume":"7","author":"Berardi","year":"1988","journal-title":"Clin Pharm"},{"key":"10.4166\/kjg.2017.70.1.4_ref33","first-page":"595","volume":"11","author":"Frank","year":"1989","journal-title":"Clin Ther"},{"key":"10.4166\/kjg.2017.70.1.4_ref34","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1136\/bmj.296.6616.195","volume":"296","author":"Weir","year":"1988","journal-title":"Br Med J (Clin Res Ed)"},{"key":"10.4166\/kjg.2017.70.1.4_ref35","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1007\/BF01537246","volume":"35","author":"Wilder-Smith","year":"1990","journal-title":"Dig Dis Sci"},{"key":"10.4166\/kjg.2017.70.1.4_ref36","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/gut.30.4.449","volume":"30","author":"Fullarton","year":"1989","journal-title":"Gut"},{"issue":"Suppl 1","key":"10.4166\/kjg.2017.70.1.4_ref37","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1365-2036.1989.tb00188.x","volume":"4","author":"Nwokolo","year":"1989","journal-title":"Aliment Pharmacol Ther"},{"key":"10.4166\/kjg.2017.70.1.4_ref38","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1046\/j.1440-1746.2003.03041.x","volume":"18","author":"Komazawa","year":"2003","journal-title":"J Gastroenterol Hepatol"},{"key":"10.4166\/kjg.2017.70.1.4_ref39","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1046\/j.1440-1746.2001.02617.x","volume":"16","author":"Adachi","year":"2001","journal-title":"J Gastroenterol Hepatol"},{"key":"10.4166\/kjg.2017.70.1.4_ref40","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1111\/j.1572-0241.1999.989_l.x","volume":"94","author":"Festen","year":"1999","journal-title":"Am J Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref41","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1046\/j.1365-2036.2000.00799.x","volume":"14","author":"Katsube","year":"2000","journal-title":"Aliment Pharmacol Ther"},{"key":"10.4166\/kjg.2017.70.1.4_ref42","first-page":"108","volume":"92","author":"Bezwoda","year":"1978","journal-title":"J Lab Clin Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref43","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/BF01298866","volume":"36","author":"Golubov","year":"1991","journal-title":"Dig Dis Sci"},{"key":"10.4166\/kjg.2017.70.1.4_ref44","first-page":"1309","volume-title":"Goodman & Gilman's the pharmacological basis of therapeutics","author":"Wallace","year":"2011","edition":"12"},{"key":"10.4166\/kjg.2017.70.1.4_ref45","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/jhm.10","volume":"1","author":"Qadeer","year":"2006","journal-title":"J Hosp Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref46","first-page":"1527","volume":"91","author":"Leite","year":"1996","journal-title":"Am J Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref47","first-page":"1532","volume":"91","author":"Kuo","year":"1996","journal-title":"Am J Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref48","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1572-0241.1998.221_a.x","volume":"93","author":"Peghini","year":"1998","journal-title":"Am J Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref49","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1046\/j.1365-2036.1998.00419.x","volume":"12","author":"Katz","year":"1998","journal-title":"Aliment Pharmacol Ther"},{"key":"10.4166\/kjg.2017.70.1.4_ref50","doi-asserted-by":"crossref","first-page":"A15","DOI":"10.1016\/S0016-5085(00)82129-0","volume":"118","author":"Fackler","year":"2000","journal-title":"Gastroenterology"},{"key":"10.4166\/kjg.2017.70.1.4_ref51","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/S0016-5085(98)70010-1","volume":"115","author":"Peghini","year":"1998","journal-title":"Gastroenterology"},{"key":"10.4166\/kjg.2017.70.1.4_ref52","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1172\/JCI107952","volume":"55","author":"Walsh","year":"1975","journal-title":"J Clin Invest"},{"key":"10.4166\/kjg.2017.70.1.4_ref53","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1136\/gut.32.3.252","volume":"32","author":"Lancaster-Smith","year":"1991","journal-title":"Gut"},{"key":"10.4166\/kjg.2017.70.1.4_ref54","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1056\/NEJM198901123200201","volume":"320","author":"Walan","year":"1989","journal-title":"N Engl J Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref55","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1001\/jama.1996.03530320046033","volume":"275","author":"Soll","year":"1996","journal-title":"JAMA"},{"key":"10.4166\/kjg.2017.70.1.4_ref56","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1001\/archinte.1987.00370100112018","volume":"147","author":"Roth","year":"1987","journal-title":"Arch Intern Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref57","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1136\/bmj.297.6655.1017","volume":"297","author":"Ehsanullah","year":"1988","journal-title":"BMJ"},{"key":"10.4166\/kjg.2017.70.1.4_ref58","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/BF01536266","volume":"34","author":"Robinson","year":"1989","journal-title":"Dig Dis Sci"},{"key":"10.4166\/kjg.2017.70.1.4_ref59","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1136\/gut.28.9.1120","volume":"28","author":"Jones","year":"1987","journal-title":"Gut"},{"key":"10.4166\/kjg.2017.70.1.4_ref60","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1056\/NEJM199605303342204","volume":"334","author":"Taha","year":"1996","journal-title":"N Engl J Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref61","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1016\/0016-5085(91)90665-8","volume":"100","author":"Graham","year":"1991","journal-title":"Gastroenterology"},{"issue":"3 Suppl 1","key":"10.4166\/kjg.2017.70.1.4_ref62","first-page":"2S","volume":"26","year":"1997","journal-title":"Hepatology"},{"key":"10.4166\/kjg.2017.70.1.4_ref63","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1136\/gut.34.6.748","volume":"34","author":"Hudson","year":"1993","journal-title":"Gut"},{"key":"10.4166\/kjg.2017.70.1.4_ref64","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1056\/NEJM199803123381104","volume":"338","author":"Yeomans","year":"1998","journal-title":"N Engl J Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref65","doi-asserted-by":"crossref","first-page":"575","DOI":"10.5056\/jnm16138","volume":"22","author":"Kim","year":"2016","journal-title":"J Neurogastroenterol Motil"},{"issue":"3","key":"10.4166\/kjg.2017.70.1.4_ref66","first-page":"CD002095","author":"van Pinxteren","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"10.4166\/kjg.2017.70.1.4_ref67","first-page":"CD003244","author":"Khan","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"10.4166\/kjg.2017.70.1.4_ref68","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/S1542-3565(04)00288-5","volume":"2","author":"Dean","year":"2004","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.4166\/kjg.2017.70.1.4_ref69","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1111\/j.1365-2036.2005.02490.x","volume":"21","author":"Zacny","year":"2005","journal-title":"Aliment Pharmacol Ther"},{"key":"10.4166\/kjg.2017.70.1.4_ref70","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1053\/gast.2002.31876","volume":"122","author":"Fackler","year":"2002","journal-title":"Gastroenterology"},{"key":"10.4166\/kjg.2017.70.1.4_ref71","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1097\/MCG.0b013e31814a4e5c","volume":"42","author":"Mainie","year":"2008","journal-title":"J Clin Gastroenterol"},{"key":"10.4166\/kjg.2017.70.1.4_ref72","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S0016-5085(81)80072-8","volume":"81","author":"Dodds","year":"1981","journal-title":"Gastroenterology"},{"key":"10.4166\/kjg.2017.70.1.4_ref73","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3109\/07853899509031939","volume":"27","author":"Isolauri","year":"1995","journal-title":"Ann Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref74","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1056\/NEJM199510263331703","volume":"333","author":"Vigneri","year":"1995","journal-title":"N Engl J Med"},{"key":"10.4166\/kjg.2017.70.1.4_ref75","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1046\/j.1440-1746.2002.02785.x","volume":"17","author":"Kawano","year":"2002","journal-title":"J Gastroenterol Hepatol"},{"key":"10.4166\/kjg.2017.70.1.4_ref76","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0014-2999(84)90706-4","volume":"106","author":"Neya","year":"1984","journal-title":"Eur J Pharmacol"},{"key":"10.4166\/kjg.2017.70.1.4_ref77","first-page":"618","volume":"49","author":"Ueki","year":"1999","journal-title":"Arzneimittelforschung"},{"key":"10.4166\/kjg.2017.70.1.4_ref78","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1159\/000339111","volume":"86","author":"Futagami","year":"2012","journal-title":"Digestion"},{"key":"10.4166\/kjg.2017.70.1.4_ref79","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1136\/gut.34.8.1025","volume":"34","author":"Inauen","year":"1993","journal-title":"Gut"},{"key":"10.4166\/kjg.2017.70.1.4_ref80","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF02811071","volume":"26","author":"Sekiguchi","year":"1991","journal-title":"Gastroenterol Jpn"},{"key":"10.4166\/kjg.2017.70.1.4_ref81","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1046\/j.1365-2036.2002.01159.x","volume":"16","author":"Adachi","year":"2002","journal-title":"Aliment Pharmacol Ther"},{"key":"10.4166\/kjg.2017.70.1.4_ref82","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1023\/B:DDAS.0000020492.16088.28","volume":"49","author":"Adachi","year":"2004","journal-title":"Dig Dis Sci"},{"key":"10.4166\/kjg.2017.70.1.4_ref83","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/S0016-5085(82)80021-8","volume":"83","author":"Sonnenberg","year":"1982","journal-title":"Gastroenterology"},{"issue":"1 Pt 1","key":"10.4166\/kjg.2017.70.1.4_ref84","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0016-5085(82)80286-2","volume":"83","author":"Helm","year":"1982","journal-title":"Gastroenterology"}],"container-title":["The Korean Journal of Gastroenterology"],"original-title":[],"language":"ko","link":[{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.4166\/kjg.2017.70.1.4","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4166\/kjg.2017.70.1.4","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4166\/kjg.2017.70.1.4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T04:42:54Z","timestamp":1719376974000},"score":1,"resource":{"primary":{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4166\/kjg.2017.70.1.4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":84,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.4166\/kjg.2017.70.1.4","relation":{},"ISSN":["1598-9992","2233-6869"],"issn-type":[{"value":"1598-9992","type":"print"},{"value":"2233-6869","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}