{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:47:28Z","timestamp":1790142448861,"version":"4.0.1"},"reference-count":36,"publisher":"XMLink","issue":"6","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPF1B0132-3"],"award-info":[{"award-number":["CMRPF1B0132-3"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG381552"],"award-info":[{"award-number":["CMRPG381552"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council Taiwan","doi-asserted-by":"publisher","award":["102-2313-B-225-003"],"award-info":[{"award-number":["102-2313-B-225-003"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Allergy Asthma Immunol Res"],"published-print":{"date-parts":[[2014]]},"DOI":"10.4168\/aair.2014.6.6.548","type":"journal-article","created":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T08:10:12Z","timestamp":1414656612000},"page":"548","update-policy":"https:\/\/doi.org\/10.4168\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Oral Lovastatin Attenuates Airway Inflammation and Mucus Secretion in Ovalbumin-Induced Murine Model of Asthma"],"prefix":"10.4168","volume":"6","author":[{"given":"Chian-Jiun","family":"Liou","sequence":"first","affiliation":[{"name":"Department of Nursing, Chang Gung University of Science and Technology, Tao-Yuan, Taiwan."},{"name":"Research Center for Industry of Human Ecology, Chang Gung University of Science and Technology, Kwei-Shan, Tao-Yuan, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Yun","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Chung","family":"Huang","sequence":"additional","affiliation":[{"name":"Research Center for Industry of Human Ecology, Chang Gung University of Science and Technology, Kwei-Shan, Tao-Yuan, Taiwan."},{"name":"Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, Kwei-Shan, Tao-Yuan, Taiwan."},{"name":"Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Kwei-Shan, Tao-Yuan, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Chi","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Chun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Ling","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiann-Jong","family":"Shen","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan."},{"name":"Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital at Lin-Kuo, Tao-Yuan, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.4168\/aair.2014.6.6.548_ref1","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/j.1365-2222.2012.03983.x","volume":"42","author":"Poon","year":"2012","journal-title":"Clin Exp Allergy"},{"key":"10.4168\/aair.2014.6.6.548_ref2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s11882-009-0081-7","volume":"10","author":"Agrawal","year":"2010","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.4168\/aair.2014.6.6.548_ref3","doi-asserted-by":"crossref","first-page":"189","DOI":"10.4168\/aair.2013.5.4.189","volume":"5","author":"Kim","year":"2013","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2014.6.6.548_ref4","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1146\/annurev.physiol.70.113006.100441","volume":"70","author":"Thai","year":"2008","journal-title":"Annu Rev Physiol"},{"key":"10.4168\/aair.2014.6.6.548_ref5","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1146\/annurev.physiol.70.113006.100638","volume":"70","author":"Davis","year":"2008","journal-title":"Annu Rev Physiol"},{"key":"10.4168\/aair.2014.6.6.548_ref6","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.pupt.2011.12.003","volume":"25","author":"Kim","year":"2012","journal-title":"Pulm Pharmacol Ther"},{"key":"10.4168\/aair.2014.6.6.548_ref7","doi-asserted-by":"crossref","first-page":"181","DOI":"10.4168\/aair.2013.5.4.181","volume":"5","author":"Suh","year":"2013","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2014.6.6.548_ref8","doi-asserted-by":"crossref","first-page":"e650","DOI":"10.1542\/peds.2012-0162","volume":"130","author":"Castro-Rodriguez","year":"2012","journal-title":"Pediatrics"},{"key":"10.4168\/aair.2014.6.6.548_ref9","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.ejphar.2005.12.052","volume":"533","author":"Barnes","year":"2006","journal-title":"Eur J Pharmacol"},{"key":"10.4168\/aair.2014.6.6.548_ref10","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1111\/j.1365-2222.2008.03119.x","volume":"38","author":"Afshar","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"10.4168\/aair.2014.6.6.548_ref11","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1183\/09031936.05.00006005","volume":"26","author":"Georas","year":"2005","journal-title":"Eur Respir J"},{"key":"10.4168\/aair.2014.6.6.548_ref12","doi-asserted-by":"crossref","first-page":"6284","DOI":"10.2174\/138161212803832335","volume":"18","author":"Koch","year":"2012","journal-title":"Curr Pharm Des"},{"key":"10.4168\/aair.2014.6.6.548_ref13","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1111\/j.2042-7158.2011.01273.x","volume":"63","author":"Tiwari","year":"2011","journal-title":"J Pharm Pharmacol"},{"key":"10.4168\/aair.2014.6.6.548_ref14","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.2174\/138161212799504803","volume":"18","author":"Antonopoulos","year":"2012","journal-title":"Curr Pharm Des"},{"key":"10.4168\/aair.2014.6.6.548_ref15","doi-asserted-by":"crossref","first-page":"885","DOI":"10.3109\/02770903.2012.721433","volume":"49","author":"Silva","year":"2012","journal-title":"J Asthma"},{"key":"10.4168\/aair.2014.6.6.548_ref16","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1165\/rcmb.2010-0041OC","volume":"44","author":"Ahmad","year":"2011","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.4168\/aair.2014.6.6.548_ref17","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1007\/s10875-011-9529-3","volume":"31","author":"Liou","year":"2011","journal-title":"J Clin Immunol"},{"key":"10.4168\/aair.2014.6.6.548_ref18","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.jep.2011.03.065","volume":"135","author":"Shen","year":"2011","journal-title":"J Ethnopharmacol"},{"key":"10.4168\/aair.2014.6.6.548_ref19","first-page":"910520","volume":"2012","author":"Huang","year":"2012","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.4168\/aair.2014.6.6.548_ref20","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1016\/j.fct.2010.06.020","volume":"48","author":"Liou","year":"2010","journal-title":"Food Chem Toxicol"},{"key":"10.4168\/aair.2014.6.6.548_ref21","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.anai.2011.08.006","volume":"107","author":"Lin","year":"2011","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.4168\/aair.2014.6.6.548_ref22","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1002\/eji.200323446","volume":"33","author":"Chuang","year":"2003","journal-title":"Eur J Immunol"},{"key":"10.4168\/aair.2014.6.6.548_ref23","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1111\/j.1365-2222.2008.02971.x","volume":"38","author":"Holgate","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"10.4168\/aair.2014.6.6.548_ref24","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1600-065X.2011.01033.x","volume":"242","author":"Proud","year":"2011","journal-title":"Immunol Rev"},{"key":"10.4168\/aair.2014.6.6.548_ref25","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.pupt.2012.04.005","volume":"25","author":"Poynter","year":"2012","journal-title":"Pulm Pharmacol Ther"},{"key":"10.4168\/aair.2014.6.6.548_ref26","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1146\/annurev.immunol.24.021605.090720","volume":"24","author":"Rothenberg","year":"2006","journal-title":"Annu Rev Immunol"},{"key":"10.4168\/aair.2014.6.6.548_ref27","doi-asserted-by":"crossref","first-page":"L705","DOI":"10.1152\/ajplung.00531.2007","volume":"294","author":"Chiba","year":"2008","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.4168\/aair.2014.6.6.548_ref28","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.4049\/jimmunol.172.4.2059","volume":"172","author":"Chen","year":"2004","journal-title":"J Immunol"},{"key":"10.4168\/aair.2014.6.6.548_ref29","doi-asserted-by":"crossref","first-page":"24s","DOI":"10.1183\/09031936.01.00229601","volume":"34","author":"Kips","year":"2001","journal-title":"Eur Respir J Suppl"},{"key":"10.4168\/aair.2014.6.6.548_ref30","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1165\/rcmb.2003-0305OC","volume":"31","author":"Tanaka","year":"2004","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.4168\/aair.2014.6.6.548_ref31","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1164\/rccm.200311-1488OC","volume":"170","author":"Leigh","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2014.6.6.548_ref32","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1111\/j.1365-2222.2011.03852.x","volume":"41","author":"Kanoh","year":"2011","journal-title":"Clin Exp Allergy"},{"key":"10.4168\/aair.2014.6.6.548_ref33","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.intimp.2012.01.012","volume":"12","author":"Xu","year":"2012","journal-title":"Int Immunopharmacol"},{"key":"10.4168\/aair.2014.6.6.548_ref34","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s00011-009-0043-5","volume":"58","author":"Chiba","year":"2009","journal-title":"Inflamm Res"},{"key":"10.4168\/aair.2014.6.6.548_ref35","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.pupt.2013.06.005","volume":"27","author":"Capra","year":"2014","journal-title":"Pulm Pharmacol Ther"},{"key":"10.4168\/aair.2014.6.6.548_ref36","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1136\/thx.2007.094540","volume":"64","author":"Imamura","year":"2009","journal-title":"Thorax"}],"container-title":["Allergy, Asthma &amp; Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2014.6.6.548","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.4168\/aair.2014.6.6.548","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2014.6.6.548","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T03:58:32Z","timestamp":1589515112000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2014.6.6.548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.4168\/aair.2014.6.6.548","relation":{},"ISSN":["2092-7355","2092-7363"],"issn-type":[{"value":"2092-7355","type":"print"},{"value":"2092-7363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2014.6.6.548","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2014.6.6.548","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2014.6.6.548","URL":"http:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2014.6.6.548","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2013-09-09","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-12-12","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-02-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-08-19","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2014 The Korean Academy of Asthma, Allergy and Clinical Immunology \u2022 The Korean Academy of Pediatric Allergy and Respiratory Disease","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}