{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:51:17Z","timestamp":1788871877180,"version":"build-2803163510"},"reference-count":36,"publisher":"XMLink","issue":"6","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2011-0026915"],"award-info":[{"award-number":["2011-0026915"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Allergy Asthma Immunol Res"],"published-print":{"date-parts":[[2014]]},"DOI":"10.4168\/aair.2014.6.6.558","type":"journal-article","created":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T04:10:19Z","timestamp":1414642219000},"page":"558","update-policy":"https:\/\/doi.org\/10.4168\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Serine Protease Inhibitor, 4-(2-aminoethyl) Benzene Sulfonyl Fluoride Hydrochloride, Reduces Allergic Inflammation in a House Dust Mite Allergic Rhinitis Mouse Model"],"prefix":"10.4168","volume":"6","author":[{"given":"Boo-Young","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyang Rim","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Hyeon","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Hee","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Jin","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo Whan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"issue":"Suppl 86","key":"10.4168\/aair.2014.6.6.558_ref1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1398-9995.2007.01620.x","volume":"63","author":"Bousquet","year":"2008","journal-title":"Allergy"},{"key":"10.4168\/aair.2014.6.6.558_ref2","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/ng1256","volume":"35","author":"Allen","year":"2003","journal-title":"Nat Genet"},{"key":"10.4168\/aair.2014.6.6.558_ref3","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0140-6736(95)10244-2","volume":"348","author":"Mao","year":"1996","journal-title":"Lancet"},{"key":"10.4168\/aair.2014.6.6.558_ref4","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1111\/j.1398-9995.2006.01233.x","volume":"61","author":"Smith","year":"2006","journal-title":"Allergy"},{"key":"10.4168\/aair.2014.6.6.558_ref5","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1159\/000151508","volume":"148","author":"Izakovicova Holla","year":"2009","journal-title":"Int Arch Allergy Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref6","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1254\/jphs.08162FP","volume":"108","author":"Ishizaki","year":"2008","journal-title":"J Pharmacol Sci"},{"key":"10.4168\/aair.2014.6.6.558_ref7","doi-asserted-by":"crossref","first-page":"e41107","DOI":"10.1371\/journal.pone.0041107","volume":"7","author":"Saw","year":"2012","journal-title":"PLoS One"},{"key":"10.4168\/aair.2014.6.6.558_ref8","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ejphar.2011.12.020","volume":"677","author":"Nabe","year":"2012","journal-title":"Eur J Pharmacol"},{"key":"10.4168\/aair.2014.6.6.558_ref9","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1631\/jzus.B0730029","volume":"9","author":"Zhou","year":"2008","journal-title":"J Zhejiang Univ Sci B"},{"key":"10.4168\/aair.2014.6.6.558_ref10","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1177\/0194599810396133","volume":"144","author":"Wang","year":"2011","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.4168\/aair.2014.6.6.558_ref11","doi-asserted-by":"crossref","first-page":"e35114","DOI":"10.1371\/journal.pone.0035114","volume":"7","author":"Cho","year":"2012","journal-title":"PLoS One"},{"key":"10.4168\/aair.2014.6.6.558_ref12","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.intimp.2009.02.011","volume":"9","author":"Takahashi","year":"2009","journal-title":"Int Immunopharmacol"},{"key":"10.4168\/aair.2014.6.6.558_ref13","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/362248a0","volume":"362","author":"Minty","year":"1993","journal-title":"Nature"},{"key":"10.4168\/aair.2014.6.6.558_ref14","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0092-8674(00)80702-3","volume":"100","author":"Szabo","year":"2000","journal-title":"Cell"},{"key":"10.4168\/aair.2014.6.6.558_ref15","doi-asserted-by":"crossref","first-page":"26983","DOI":"10.1074\/jbc.M403688200","volume":"279","author":"Yamashita","year":"2004","journal-title":"J Biol Chem"},{"key":"10.4168\/aair.2014.6.6.558_ref16","doi-asserted-by":"crossref","first-page":"4255","DOI":"10.4049\/jimmunol.175.7.4255","volume":"175","author":"Fields","year":"2005","journal-title":"J Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref17","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1084\/jem.20050940","volume":"202","author":"Ko","year":"2005","journal-title":"J Exp Med"},{"key":"10.4168\/aair.2014.6.6.558_ref18","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.4049\/jimmunol.1001539","volume":"186","author":"Marino","year":"2011","journal-title":"J Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref19","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1164\/ajrccm\/137.5.1002","volume":"137","author":"Wenzel","year":"1988","journal-title":"Am Rev Respir Dis"},{"key":"10.4168\/aair.2014.6.6.558_ref20","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1164\/rccm.200503-369OC","volume":"172","author":"Simpson","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2014.6.6.558_ref21","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1378\/chest.128.2.1069","volume":"128","author":"Inoue","year":"2005","journal-title":"Chest"},{"key":"10.4168\/aair.2014.6.6.558_ref22","doi-asserted-by":"crossref","first-page":"e41107","DOI":"10.1371\/journal.pone.0041107","volume":"7","author":"Saw","year":"2012","journal-title":"PLoS One"},{"key":"10.4168\/aair.2014.6.6.558_ref23","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.4049\/jimmunol.168.4.1992","volume":"168","author":"Oh","year":"2002","journal-title":"J Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref24","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1038\/sj.bjp.0701905","volume":"124","author":"Winton","year":"1998","journal-title":"Br J Pharmacol"},{"issue":"Suppl 1","key":"10.4168\/aair.2014.6.6.558_ref25","doi-asserted-by":"crossref","first-page":"S116","DOI":"10.1002\/eji.200737593","volume":"37","author":"Sakaguchi","year":"2007","journal-title":"Eur J Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref26","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/j.1600-065X.2011.01018.x","volume":"241","author":"Rudensky","year":"2011","journal-title":"Immunol Rev"},{"issue":"Suppl 1","key":"10.4168\/aair.2014.6.6.558_ref27","doi-asserted-by":"crossref","first-page":"S116","DOI":"10.1002\/eji.200737593","volume":"37","author":"Sakaguchi","year":"2007","journal-title":"Eur J Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref28","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/ncprheum0624","volume":"3","author":"Valencia","year":"2007","journal-title":"Nat Clin Pract Rheumatol"},{"key":"10.4168\/aair.2014.6.6.558_ref29","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/S0140-6736(04)15592-X","volume":"363","author":"Ling","year":"2004","journal-title":"Lancet"},{"key":"10.4168\/aair.2014.6.6.558_ref30","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.smim.2006.01.010","volume":"18","author":"Waldmann","year":"2006","journal-title":"Semin Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref31","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0952-7915(03)00098-0","volume":"15","author":"Graca","year":"2003","journal-title":"Curr Opin Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref32","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nri3227","volume":"12","author":"Wood","year":"2012","journal-title":"Nat Rev Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref33","doi-asserted-by":"crossref","first-page":"4848","DOI":"10.4049\/jimmunol.165.9.4848","volume":"165","author":"Cottrez","year":"2000","journal-title":"J Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref34","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/mi.2010.51","volume":"4","author":"Navarro","year":"2011","journal-title":"Mucosal Immunol"},{"key":"10.4168\/aair.2014.6.6.558_ref35","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/83713","volume":"27","author":"Bennett","year":"2001","journal-title":"Nat Genet"},{"key":"10.4168\/aair.2014.6.6.558_ref36","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.immuni.2009.04.010","volume":"30","author":"Shevach","year":"2009","journal-title":"Immunity"}],"container-title":["Allergy, Asthma & Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2014.6.6.558","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.4168\/aair.2014.6.6.558","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2014.6.6.558","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T23:58:33Z","timestamp":1589500713000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2014.6.6.558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.4168\/aair.2014.6.6.558","relation":{},"ISSN":["2092-7355","2092-7363"],"issn-type":[{"value":"2092-7355","type":"print"},{"value":"2092-7363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2014.6.6.558","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2014.6.6.558","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2014.6.6.558","URL":"http:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2014.6.6.558","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2013-09-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-10","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-06","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-09-24","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2014 The Korean Academy of Asthma, Allergy and Clinical Immunology \u2022 The Korean Academy of Pediatric Allergy and Respiratory Disease","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}