{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T12:42:50Z","timestamp":1748608970515,"version":"3.37.3"},"reference-count":58,"publisher":"XMLink","issue":"5","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100002457","name":"Chosun University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002457","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Allergy Asthma Immunol Res"],"published-print":{"date-parts":[[2016]]},"DOI":"10.4168\/aair.2016.8.5.445","type":"journal-article","created":{"date-parts":[[2016,6,17]],"date-time":"2016-06-17T06:27:13Z","timestamp":1466144833000},"page":"445","update-policy":"https:\/\/doi.org\/10.4168\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Synergistic Effect of<i>Dermatophagoides farinae<\/i>and Lipopolysaccharides in Human Middle ear Epithelial Cells"],"prefix":"10.4168","volume":"8","author":[{"given":"Ji-Eun","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Chosun University College of Medicine, Gwangju, Korea."},{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Graduate school of Medicine, Seoul National University, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeon Hoo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Chosun University College of Medicine, Gwangju, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chae-Seo","family":"Rhee","sequence":"additional","affiliation":[{"name":"Sensory Organ Research Center, Seoul National University Biomedical Research Institute, Seoul, Korea."},{"name":"Institute of Allergy and Clinical Immunology, Seoul National University Biomedical Research Institute, Seoul, Korea."},{"name":"Graduate School of Immunology, Seoul National University, Seoul, Korea."},{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","reference":[{"key":"10.4168\/aair.2016.8.5.445_ref1","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1136\/adc.52.8.613","volume":"52","author":"Blair","year":"1977","journal-title":"Arch Dis Child"},{"key":"10.4168\/aair.2016.8.5.445_ref2","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1398-9995.1983.tb00852.x","volume":"38","author":"Pedersen","year":"1983","journal-title":"Allergy"},{"key":"10.4168\/aair.2016.8.5.445_ref3","doi-asserted-by":"crossref","first-page":"e63","DOI":"10.2500\/ajra.2013.27.3877","volume":"27","author":"Kim","year":"2013","journal-title":"Am J Rhinol Allergy"},{"key":"10.4168\/aair.2016.8.5.445_ref4","first-page":"154","volume":"14","author":"D\u00f6ner","year":"2004","journal-title":"J Investig Allergol Clin Immunol"},{"key":"10.4168\/aair.2016.8.5.445_ref5","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1177\/019459988509300508","volume":"93","author":"Bernstein","year":"1985","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.4168\/aair.2016.8.5.445_ref6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1067\/mai.2002.125697","volume":"110","author":"Sobol","year":"2002","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2016.8.5.445_ref7","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1067\/mhn.2000.109472","volume":"123","author":"Wright","year":"2000","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.4168\/aair.2016.8.5.445_ref8","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1034\/j.1398-9995.2000.00289.x","volume":"55","author":"Hurst","year":"2000","journal-title":"Allergy"},{"key":"10.4168\/aair.2016.8.5.445_ref9","doi-asserted-by":"crossref","first-page":"13766","DOI":"10.1073\/pnas.250476497","volume":"97","author":"Ozinsky","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.4168\/aair.2016.8.5.445_ref10","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/90609","volume":"2","author":"Akira","year":"2001","journal-title":"Nat Immunol"},{"key":"10.4168\/aair.2016.8.5.445_ref11","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1248\/bpb.b13-00595","volume":"37","author":"Kitajima","year":"2014","journal-title":"Biol Pharm Bull"},{"key":"10.4168\/aair.2016.8.5.445_ref12","doi-asserted-by":"crossref","first-page":"10689","DOI":"10.1074\/jbc.274.16.10689","volume":"274","author":"Chow","year":"1999","journal-title":"J Biol Chem"},{"key":"10.4168\/aair.2016.8.5.445_ref13","first-page":"E17","volume":"88","author":"Vlastos","year":"2009","journal-title":"Ear Nose Throat J"},{"key":"10.4168\/aair.2016.8.5.445_ref14","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1398-9995.2007.01341.x","volume":"62","author":"Papadopoulos","year":"2007","journal-title":"Allergy"},{"key":"10.4168\/aair.2016.8.5.445_ref15","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1111\/j.1398-9995.2010.02505.x","volume":"66","author":"Papadopoulos","year":"2011","journal-title":"Allergy"},{"key":"10.4168\/aair.2016.8.5.445_ref16","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1164\/rccm.200312-1647OC","volume":"170","author":"Copenhaver","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2016.8.5.445_ref17","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1042\/CS20130174","volume":"126","author":"Rochlitzer","year":"2014","journal-title":"Clin Sci (Lond)"},{"key":"10.4168\/aair.2016.8.5.445_ref18","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1399-3038.1997.tb00164.x","volume":"8","author":"Rizzo","year":"1997","journal-title":"Pediatr Allergy Immunol"},{"key":"10.4168\/aair.2016.8.5.445_ref19","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1164\/ajrccm.154.6.8970348","volume":"154","author":"Michel","year":"1996","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2016.8.5.445_ref20","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.ijporl.2011.12.003","volume":"76","author":"Song","year":"2012","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.4168\/aair.2016.8.5.445_ref21","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1002\/lary.21014","volume":"120","author":"Preciado","year":"2010","journal-title":"Laryngoscope"},{"key":"10.4168\/aair.2016.8.5.445_ref22","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.ijporl.2012.04.017","volume":"76","author":"Jun","year":"2012","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.4168\/aair.2016.8.5.445_ref23","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0008-8749(03)00059-5","volume":"221","author":"Smirnova","year":"2003","journal-title":"Cell Immunol"},{"key":"10.4168\/aair.2016.8.5.445_ref24","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1165\/rcmb.2006-0035SF","volume":"34","author":"Voynow","year":"2006","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.4168\/aair.2016.8.5.445_ref25","first-page":"L413","volume":"263","author":"Rose","year":"1992","journal-title":"Am J Physiol"},{"key":"10.4168\/aair.2016.8.5.445_ref26","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1152\/physrev.00010.2005","volume":"86","author":"Rose","year":"2006","journal-title":"Physiol Rev"},{"key":"10.4168\/aair.2016.8.5.445_ref27","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1097\/MLG.0b013e31806db531","volume":"117","author":"Kerschner","year":"2007","journal-title":"Laryngoscope"},{"key":"10.4168\/aair.2016.8.5.445_ref28","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1001\/archotol.1982.00790570029007","volume":"108","author":"Giebink","year":"1982","journal-title":"Arch Otolaryngol"},{"key":"10.4168\/aair.2016.8.5.445_ref29","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1146\/annurev.physiol.70.113006.100441","volume":"70","author":"Thai","year":"2008","journal-title":"Annu Rev Physiol"},{"key":"10.4168\/aair.2016.8.5.445_ref30","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1475-097X.2011.01039.x","volume":"31","author":"Alenmyr","year":"2011","journal-title":"Clin Physiol Funct Imaging"},{"key":"10.4168\/aair.2016.8.5.445_ref31","doi-asserted-by":"crossref","first-page":"6676","DOI":"10.1074\/jbc.M412722200","volume":"280","author":"Cho","year":"2005","journal-title":"J Biol Chem"},{"key":"10.4168\/aair.2016.8.5.445_ref32","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1177\/000348940411300812","volume":"113","author":"Lee","year":"2004","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.4168\/aair.2016.8.5.445_ref33","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1152\/physrev.00048.2006","volume":"87","author":"Yoshida","year":"2007","journal-title":"Physiol Rev"},{"key":"10.4168\/aair.2016.8.5.445_ref34","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1289\/ehp.02110665","volume":"110","author":"Spannhake","year":"2002","journal-title":"Environ Health Perspect"},{"key":"10.4168\/aair.2016.8.5.445_ref35","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1046\/j.1365-2567.2003.01539.x","volume":"108","author":"Foster","year":"2003","journal-title":"Immunology"},{"key":"10.4168\/aair.2016.8.5.445_ref36","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.4049\/jimmunol.171.2.1001","volume":"171","author":"Rodr\u00edguez","year":"2003","journal-title":"J Immunol"},{"key":"10.4168\/aair.2016.8.5.445_ref37","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1084\/jem.20021340","volume":"196","author":"Eisenbarth","year":"2002","journal-title":"J Exp Med"},{"key":"10.4168\/aair.2016.8.5.445_ref38","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1165\/rcmb.2012-0331OC","volume":"48","author":"Daan de Boer","year":"2013","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.4168\/aair.2016.8.5.445_ref39","doi-asserted-by":"crossref","first-page":"6718","DOI":"10.4049\/jimmunol.163.12.6718","volume":"163","author":"O'Neil","year":"1999","journal-title":"J Immunol"},{"key":"10.4168\/aair.2016.8.5.445_ref40","doi-asserted-by":"crossref","first-page":"4186","DOI":"10.1073\/pnas.0306906101","volume":"101","author":"Gioannini","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.4168\/aair.2016.8.5.445_ref41","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/icb.2008.75","volume":"87","author":"Zhang","year":"2009","journal-title":"Immunol Cell Biol"},{"key":"10.4168\/aair.2016.8.5.445_ref42","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1084\/jem.189.11.1777","volume":"189","author":"Shimazu","year":"1999","journal-title":"J Exp Med"},{"key":"10.4168\/aair.2016.8.5.445_ref43","doi-asserted-by":"crossref","first-page":"497","DOI":"10.4168\/aair.2015.7.5.497","volume":"7","author":"Liao","year":"2015","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2016.8.5.445_ref44","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1126\/science.1139111","volume":"316","author":"Ohto","year":"2007","journal-title":"Science"},{"key":"10.4168\/aair.2016.8.5.445_ref45","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0022-2836(02)00027-X","volume":"318","author":"Derewenda","year":"2002","journal-title":"J Mol Biol"},{"key":"10.4168\/aair.2016.8.5.445_ref46","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.cell.2007.08.002","volume":"130","author":"Kim","year":"2007","journal-title":"Cell"},{"key":"10.4168\/aair.2016.8.5.445_ref47","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/nature07548","volume":"457","author":"Trompette","year":"2009","journal-title":"Nature"},{"key":"10.4168\/aair.2016.8.5.445_ref48","doi-asserted-by":"crossref","first-page":"393","DOI":"10.4168\/aair.2015.7.4.393","volume":"7","author":"Yin","year":"2015","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2016.8.5.445_ref49","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jaci.2012.07.050","volume":"131","author":"Ryu","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2016.8.5.445_ref50","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1146\/annurev-physiol-012110-142250","volume":"73","author":"Lee","year":"2011","journal-title":"Annu Rev Physiol"},{"key":"10.4168\/aair.2016.8.5.445_ref51","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature05746","volume":"447","author":"Reese","year":"2007","journal-title":"Nature"},{"key":"10.4168\/aair.2016.8.5.445_ref52","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000065179","volume":"129","author":"Thomas","year":"2002","journal-title":"Int Arch Allergy Immunol"},{"key":"10.4168\/aair.2016.8.5.445_ref53","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.molmed.2010.04.008","volume":"16","author":"Thomas","year":"2010","journal-title":"Trends Mol Med"},{"key":"10.4168\/aair.2016.8.5.445_ref54","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1111\/j.1365-2443.2009.01334.x","volume":"14","author":"Ichikawa","year":"2009","journal-title":"Genes Cells"},{"key":"10.4168\/aair.2016.8.5.445_ref55","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1056\/NEJMoa020057","volume":"347","author":"Braun-Fahrl\u00e4nder","year":"2002","journal-title":"N Engl J Med"},{"key":"10.4168\/aair.2016.8.5.445_ref56","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1164\/rccm.200203-256OC","volume":"166","author":"Gehring","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2016.8.5.445_ref57","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/S0140-6736(01)06252-3","volume":"358","author":"Riedler","year":"2001","journal-title":"Lancet"},{"key":"10.4168\/aair.2016.8.5.445_ref58","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/35095579","volume":"1","author":"Wills-Karp","year":"2001","journal-title":"Nat Rev Immunol"}],"container-title":["Allergy, Asthma &amp; Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/synapse.koreamed.org\/pdf\/10.4168\/aair.2016.8.5.445","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2016.8.5.445","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2016.8.5.445","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T22:49:19Z","timestamp":1692398959000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2016.8.5.445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":58,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.4168\/aair.2016.8.5.445","relation":{},"ISSN":["2092-7355","2092-7363"],"issn-type":[{"type":"print","value":"2092-7355"},{"type":"electronic","value":"2092-7363"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2016.8.5.445","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2016.8.5.445","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2016.8.5.445","URL":"http:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2016.8.5.445","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2015-12-07","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-01-03","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-01-06","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-03-29","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2016 The Korean Academy of Asthma, Allergy and Clinical Immunology \u2022 The Korean Academy of Pediatric Allergy and Respiratory Disease","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}