{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T15:59:04Z","timestamp":1785599944707,"version":"3.56.0"},"reference-count":32,"publisher":"XMLink","issue":"5","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control & Prevention","doi-asserted-by":"publisher","award":["2015-ER6601-00"],"award-info":[{"award-number":["2015-ER6601-00"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Korea Institute of Child Care and Education"}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Allergy Asthma Immunol Res"],"published-print":{"date-parts":[[2018]]},"DOI":"10.4168\/aair.2018.10.5.466","type":"journal-article","created":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T08:58:01Z","timestamp":1533632281000},"page":"466","update-policy":"https:\/\/doi.org\/10.4168\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prevalence, Risk Factors and Cutoff Values for Bronchial Hyperresponsiveness to Provocholine in 7-Year-Old Children"],"prefix":"10.4168","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0559-4982","authenticated-orcid":false,"given":"Sungsu","family":"Jung","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Childhood Asthma Atopy Center, Environmental Health Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7817-8728","authenticated-orcid":false,"given":"Dong In","family":"Suh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Seoul National University Hospital, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2499-0702","authenticated-orcid":false,"given":"So-Yeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Childhood Asthma Atopy Center, Environmental Health Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4904-9118","authenticated-orcid":false,"given":"Jisun","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Childhood Asthma Atopy Center, Environmental Health Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4282-4000","authenticated-orcid":false,"given":"Hyun-Ju","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, International St. Mary's Hospital, Catholic Kwandong University Hospital, Incheon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7120-8130","authenticated-orcid":false,"given":"Young-Ho","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Childhood Asthma Atopy Center, Environmental Health Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9648-4585","authenticated-orcid":false,"given":"Song-I","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Hallym University Sacred Heart Hospital, Anyang, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5129-928X","authenticated-orcid":false,"given":"Ji-Won","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwang Cheon","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, National Health Insurance Service Ilsan Hospital, Goyang, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1527-6782","authenticated-orcid":false,"given":"Yong Han","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1896-6279","authenticated-orcid":false,"given":"Sung-Il","family":"Woo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, College of Medicine, Chungbuk National University, Cheongju, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You-Sook","family":"Youn","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The Catholic University of Korea College of Medicine, Daejeon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3983-9770","authenticated-orcid":false,"given":"Kang Seo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Presbyterian Medical Center, Jeonju, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2458-8529","authenticated-orcid":false,"given":"Hwa Jin","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung-Hee","family":"Kook","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Gwangju Veterans Hospital, Gwangju, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hye Ryoung","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Gwangju Veterans Hospital, Gwangju, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5364-5318","authenticated-orcid":false,"given":"Hai Lee","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Catholic University of Daegu School of Medicine, Daegu, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0691-1924","authenticated-orcid":false,"given":"Ja Hyeong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Ulsan University Hospital, Ulsan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8591-1783","authenticated-orcid":false,"given":"Hyung Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pusan National University Yangsan Hospital, Yangsan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin A","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Dong-A University College of Medicine, Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8849-9341","authenticated-orcid":false,"given":"Hyang-Ok","family":"Woo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Health Science Institute, Gyeongsang National University College of Medicine, Jinju, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1409-2113","authenticated-orcid":false,"given":"Soo-Jong","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Childhood Asthma Atopy Center, Environmental Health Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.4168\/aair.2018.10.5.466_ref1","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.jaip.2016.11.030","volume":"5","author":"Nair","year":"2017","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.4168\/aair.2018.10.5.466_ref2","doi-asserted-by":"crossref","first-page":"e63","DOI":"10.2500\/ajra.2013.27.3877","volume":"27","author":"Kim","year":"2013","journal-title":"Am J Rhinol Allergy"},{"key":"10.4168\/aair.2018.10.5.466_ref3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s12890-017-0387-5","volume":"17","author":"Lee","year":"2017","journal-title":"BMC Pulm Med"},{"key":"10.4168\/aair.2018.10.5.466_ref4","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1002\/ppul.23433","volume":"51","author":"Kim","year":"2016","journal-title":"Pediatr Pulmonol"},{"key":"10.4168\/aair.2018.10.5.466_ref5","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.jaci.2014.12.1927","volume":"136","author":"Thomas","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2018.10.5.466_ref6","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.rmed.2014.01.009","volume":"108","author":"Harmsen","year":"2014","journal-title":"Respir Med"},{"key":"10.4168\/aair.2018.10.5.466_ref7","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/1465-9921-6-131","volume":"6","author":"Jayet","year":"2005","journal-title":"Respir Res"},{"key":"10.4168\/aair.2018.10.5.466_ref8","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1164\/rccm.200304-556OC","volume":"169","author":"Joseph-Bowen","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2018.10.5.466_ref9","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1164\/ajrccm.156.5.9701060","volume":"156","author":"Leynaert","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2018.10.5.466_ref10","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1056\/NEJM199110103251504","volume":"325","author":"Sears","year":"1991","journal-title":"N Engl J Med"},{"key":"10.4168\/aair.2018.10.5.466_ref11","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1136\/thx.2005.052241","volume":"61","author":"Brutsche","year":"2006","journal-title":"Thorax"},{"key":"10.4168\/aair.2018.10.5.466_ref12","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1002\/ppul.21312","volume":"45","author":"Kim","year":"2010","journal-title":"Pediatr Pulmonol"},{"key":"10.4168\/aair.2018.10.5.466_ref13","doi-asserted-by":"crossref","first-page":"E181","DOI":"10.1503\/cmaj.080612","volume":"181","author":"Subbarao","year":"2009","journal-title":"CMAJ"},{"key":"10.4168\/aair.2018.10.5.466_ref14","first-page":"28","volume":"20","author":"Homer","year":"2005","journal-title":"Physiology (Bethesda)"},{"key":"10.4168\/aair.2018.10.5.466_ref15","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1067\/mai.2003.162","volume":"111","author":"Taussig","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2018.10.5.466_ref16","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s12884-015-0505-4","volume":"15","author":"Bahk","year":"2015","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.4168\/aair.2018.10.5.466_ref17","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1164\/ajrccm.161.1.ats11-99","volume":"161","author":"Crapo","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2018.10.5.466_ref18","doi-asserted-by":"crossref","first-page":"61","DOI":"10.4168\/aair.2010.2.2.61","volume":"2","author":"Lee","year":"2010","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2018.10.5.466_ref19","doi-asserted-by":"crossref","first-page":"769","DOI":"10.5124\/jkma.2011.54.7.769","volume":"54","author":"Ahn","year":"2011","journal-title":"J Korean Med Assoc"},{"key":"10.4168\/aair.2018.10.5.466_ref20","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4168\/aair.2011.3.1.27","volume":"3","author":"Kwon","year":"2011","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2018.10.5.466_ref21","doi-asserted-by":"crossref","first-page":"343","DOI":"10.3345\/kjp.2008.51.4.343","volume":"51","author":"Hong","year":"2008","journal-title":"Korean J Pediatr"},{"key":"10.4168\/aair.2018.10.5.466_ref22","doi-asserted-by":"crossref","first-page":"391","DOI":"10.4168\/aair.2016.8.5.391","volume":"8","author":"D'Amato","year":"2016","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2018.10.5.466_ref23","doi-asserted-by":"crossref","first-page":"171","DOI":"10.4168\/aard.2014.2.3.171","volume":"2","author":"Kim","year":"2014","journal-title":"Allergy Asthma Respir Dis"},{"key":"10.4168\/aair.2018.10.5.466_ref24","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1378\/chest.127.2.502","volume":"127","author":"Arshad","year":"2005","journal-title":"Chest"},{"key":"10.4168\/aair.2018.10.5.466_ref25","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1378\/chest.122.3.812","volume":"122","author":"Schwartz","year":"2002","journal-title":"Chest"},{"key":"10.4168\/aair.2018.10.5.466_ref26","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/ppul.20228","volume":"40","author":"Futrakul","year":"2005","journal-title":"Pediatr Pulmonol"},{"key":"10.4168\/aair.2018.10.5.466_ref27","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1183\/09031936.02.00962002","volume":"20","author":"Ernst","year":"2002","journal-title":"Eur Respir J"},{"key":"10.4168\/aair.2018.10.5.466_ref28","first-page":"625","volume":"120","author":"Polgar","year":"1979","journal-title":"Am Rev Respir Dis"},{"key":"10.4168\/aair.2018.10.5.466_ref29","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1378\/chest.93.5.1076","volume":"93","author":"Busse","year":"1988","journal-title":"Chest"},{"key":"10.4168\/aair.2018.10.5.466_ref30","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1378\/chest.102.4.1104","volume":"102","author":"Zhong","year":"1992","journal-title":"Chest"},{"key":"10.4168\/aair.2018.10.5.466_ref31","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s12519-017-0026-5","volume":"13","author":"Lee","year":"2017","journal-title":"World J Pediatr"},{"key":"10.4168\/aair.2018.10.5.466_ref32","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1136\/thoraxjnl-2011-200901","volume":"67","author":"Mitchell","year":"2012","journal-title":"Thorax"}],"container-title":["Allergy, Asthma & Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.4168\/aair.2018.10.5.466","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2018.10.5.466","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2018.10.5.466","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T04:00:53Z","timestamp":1589515253000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2018.10.5.466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.4168\/aair.2018.10.5.466","relation":{},"ISSN":["2092-7355","2092-7363"],"issn-type":[{"value":"2092-7355","type":"print"},{"value":"2092-7363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2018.10.5.466","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4168\/aair.2018.10.5.466","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2018.10.5.466","URL":"http:\/\/e-aair.org\/DOIxphp?id=10.4168\/aair.2018.10.5.466","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2017-12-07","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-30","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-25","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2018 The Korean Academy of Asthma, Allergy and Clinical Immunology \u2022 The Korean Academy of Pediatric Allergy and Respiratory Disease","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}