{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:37:46Z","timestamp":1791315466806,"version":"4.3.1"},"reference-count":42,"publisher":"XMLink","issue":"2","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI16C0992"],"award-info":[{"award-number":["HI16C0992"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Green Cross Co"},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NFR-2017R1C1B5076565"],"award-info":[{"award-number":["NFR-2017R1C1B5076565"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["e-aair.org"],"crossmark-restriction":false},"short-container-title":["Allergy Asthma Immunol Res"],"DOI":"10.4168\/aair.2021.13.2.271","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T01:18:30Z","timestamp":1611019110000},"page":"271","update-policy":"https:\/\/doi.org\/10.4168\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Specific Antibody Deficiency in Adult Patients With IgG or IgG Subclass Deficiency"],"prefix":"10.4168","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1572-5149","authenticated-orcid":false,"given":"Joo-Hee","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4225-7117","authenticated-orcid":false,"given":"Jae-Hyuk","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7124-9434","authenticated-orcid":false,"given":"So-Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8371-3513","authenticated-orcid":false,"given":"Eun-Mi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5457-5780","authenticated-orcid":false,"given":"Seung Hun","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6878-6543","authenticated-orcid":false,"given":"Ki-Suck","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2614-0303","authenticated-orcid":false,"given":"Hae-Sim","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2021]]},"reference":[{"key":"10.4168\/aair.2021.13.2.271_ref1","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/j.jaci.2015.04.049","volume":"136","author":"Bonilla","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref2","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.jaip.2019.01.024","volume":"7","author":"Sorensen","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.4168\/aair.2021.13.2.271_ref3","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/(SICI)1099-0496(199609)22:3<167::AID-PPUL5>3.0.CO;2-M","volume":"22","author":"Sorensen","year":"1996","journal-title":"Pediatr Pulmonol"},{"key":"10.4168\/aair.2021.13.2.271_ref4","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S1081-1206(10)60035-X","volume":"76","author":"Hidalgo","year":"1996","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref5","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0022-3476(05)81598-7","volume":"116","author":"Shackelford","year":"1990","journal-title":"J Pediatr"},{"key":"10.4168\/aair.2021.13.2.271_ref6","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1365-2249.2009.04062.x","volume":"159","author":"Abrahamian","year":"2010","journal-title":"Clin Exp Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref7","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1056\/NEJM198511143132002","volume":"313","author":"Umetsu","year":"1985","journal-title":"N Engl J Med"},{"key":"10.4168\/aair.2021.13.2.271_ref8","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.it.2019.01.005","volume":"40","author":"Damelang","year":"2019","journal-title":"Trends Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref9","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ebiom.2017.01.014","volume":"16","author":"Jounai","year":"2017","journal-title":"EBioMedicine"},{"key":"10.4168\/aair.2021.13.2.271_ref10","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/ncomms1608","volume":"2","author":"Stapleton","year":"2011","journal-title":"Nat Commun"},{"key":"10.4168\/aair.2021.13.2.271_ref11","doi-asserted-by":"crossref","first-page":"e64024","DOI":"10.1371\/journal.pone.0064024","volume":"8","author":"Cao","year":"2013","journal-title":"PLoS One"},{"key":"10.4168\/aair.2021.13.2.271_ref12","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.3389\/fimmu.2018.02384","volume":"9","author":"Janssen","year":"2018","journal-title":"Front Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref13","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s12026-018-8996-5","volume":"66","author":"Modell","year":"2018","journal-title":"Immunol Res"},{"key":"10.4168\/aair.2021.13.2.271_ref14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s10875-016-0236-y","volume":"36","author":"Schatorj\u00e9","year":"2016","journal-title":"J Clin Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref15","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1128\/CDLI.10.4.514-519.2003","volume":"10","author":"Wernette","year":"2003","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref16","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.3346\/jkms.2017.32.10.1581","volume":"32","author":"Lee","year":"2017","journal-title":"J Korean Med Sci"},{"key":"10.4168\/aair.2021.13.2.271_ref17","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.iac.2015.07.003","volume":"35","author":"Wall","year":"2015","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.4168\/aair.2021.13.2.271_ref18","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s10875-017-0465-8","volume":"38","author":"Bousfiha","year":"2018","journal-title":"J Clin Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref19","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1007\/s10875-013-9919-9","volume":"33","author":"Della Libera","year":"2013","journal-title":"J Clin Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref20","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nri3466","volume":"13","author":"Durandy","year":"2013","journal-title":"Nat Rev Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref21","doi-asserted-by":"crossref","first-page":"292","DOI":"10.4168\/aair.2020.12.2.292","volume":"12","author":"Kwon","year":"2020","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2021.13.2.271_ref22","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.3389\/fimmu.2019.02593","volume":"10","author":"Edwards","year":"2019","journal-title":"Front Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref23","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1007\/s10875-020-00773-y","volume":"40","author":"Shin","year":"2020","journal-title":"J Clin Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref24","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.jaci.2019.02.017","volume":"144","author":"Blanco","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref25","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1056\/NEJM198007243030402","volume":"303","author":"Siber","year":"1980","journal-title":"N Engl J Med"},{"key":"10.4168\/aair.2021.13.2.271_ref26","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12865-019-0310-3","volume":"20","author":"Parker","year":"2019","journal-title":"BMC Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref27","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1128\/CDLI.11.6.1158-1164.2004","volume":"11","author":"Mikolajczyk","year":"2004","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref28","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1086\/600045","volume":"49","author":"Jansen","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.4168\/aair.2021.13.2.271_ref29","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S2213-2600(15)00202-7","volume":"3","author":"Verma","year":"2015","journal-title":"Lancet Respir Med"},{"key":"10.4168\/aair.2021.13.2.271_ref30","doi-asserted-by":"crossref","first-page":"180019","DOI":"10.1183\/16000617.0019-2018","volume":"27","author":"Cinetto","year":"2018","journal-title":"Eur Respir Rev"},{"key":"10.4168\/aair.2021.13.2.271_ref31","doi-asserted-by":"crossref","first-page":"604","DOI":"10.4168\/aair.2019.11.5.604","volume":"11","author":"Hur","year":"2019","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2021.13.2.271_ref32","doi-asserted-by":"crossref","first-page":"526","DOI":"10.4168\/aair.2017.9.6.526","volume":"9","author":"Kim","year":"2017","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2021.13.2.271_ref33","first-page":"449","volume":"35","author":"Lee","year":"2020","journal-title":"Korean J Intern Med (Korean Assoc Intern Med)"},{"key":"10.4168\/aair.2021.13.2.271_ref34","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.cellimm.2015.09.004","volume":"299","author":"Barton","year":"2016","journal-title":"Cell Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref35","doi-asserted-by":"crossref","first-page":"e0216940","DOI":"10.1371\/journal.pone.0216940","volume":"14","author":"Barton","year":"2019","journal-title":"PLoS One"},{"key":"10.4168\/aair.2021.13.2.271_ref36","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.3389\/fimmu.2019.01541","volume":"10","author":"Ameratunga","year":"2019","journal-title":"Front Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref37","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1007\/s10875-016-0335-9","volume":"36","author":"Dupin","year":"2016","journal-title":"J Clin Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref38","author":"Leitao Filho","year":"2020","journal-title":"Chest"},{"key":"10.4168\/aair.2021.13.2.271_ref39","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1007\/s10875-012-9814-9","volume":"33 Suppl 1","author":"Leiva","year":"2013","journal-title":"J Clin Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref40","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/s10875-019-00716-2","volume":"40","author":"Hajjar","year":"2020","journal-title":"J Clin Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref41","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1128\/CVI.00086-12","volume":"19","author":"Burton","year":"2012","journal-title":"Clin Vaccine Immunol"},{"key":"10.4168\/aair.2021.13.2.271_ref42","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/s10156-013-0601-1","volume":"19","author":"Song","year":"2013","journal-title":"J Infect Chemother"}],"container-title":["Allergy, Asthma &amp; Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/e-aair.org\/pdf\/10.4168\/aair.2021.13.2.271","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2021.13.2.271","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2021.13.2.271","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T01:24:36Z","timestamp":1611019476000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2021.13.2.271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":42,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4168\/aair.2021.13.2.271","relation":{},"ISSN":["2092-7355","2092-7363"],"issn-type":[{"value":"2092-7355","type":"print"},{"value":"2092-7363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"2020-06-17","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-24","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-31","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-12","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2021 The Korean Academy of Asthma, Allergy and Clinical Immunology \u2022 The Korean Academy of Pediatric Allergy and Respiratory Disease","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}