{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T22:12:47Z","timestamp":1784326367596,"version":"3.55.0"},"reference-count":28,"publisher":"XMLink","issue":"3","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Taipei City Hospital","award":["10801-4-001"],"award-info":[{"award-number":["10801-4-001"]}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V111B-043"],"award-info":[{"award-number":["V111B-043"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["e-aair.org"],"crossmark-restriction":false},"short-container-title":["Allergy Asthma Immunol Res"],"DOI":"10.4168\/aair.2022.14.3.314","type":"journal-article","created":{"date-parts":[[2022,5,13]],"date-time":"2022-05-13T06:55:53Z","timestamp":1652424953000},"page":"314","update-policy":"https:\/\/doi.org\/10.4168\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cardiovascular Medication Use and Risk of Acute Exacerbation in Patients With Asthma-COPD Overlap (CVACO Study)"],"prefix":"10.4168","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9304-2856","authenticated-orcid":false,"given":"Vincent Yi-Fong","family":"Su","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Taipei City Hospital, Taipei, Taiwan."},{"name":"Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan."},{"name":"Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4355-202X","authenticated-orcid":false,"given":"Szu-Wen","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Taipei Veterans General Hospital, Taipei, Taiwan."},{"name":"Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9795-1747","authenticated-orcid":false,"given":"Yuh-Lih","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Taipei Veterans General Hospital, Taipei, Taiwan."},{"name":"Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan."},{"name":"Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7191-0974","authenticated-orcid":false,"given":"Yueh-Ching","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Taipei Veterans General Hospital, Taipei, Taiwan."},{"name":"Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan."},{"name":"Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan."},{"name":"School of Pharmacy, Taipei Medical University, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7455-9593","authenticated-orcid":false,"given":"Hsin-Chen","family":"Lee","sequence":"additional","affiliation":[{"name":"Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2803-980X","authenticated-orcid":false,"given":"Kuang-Yao","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan."},{"name":"Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan."},{"name":"Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan."},{"name":"Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4822-5474","authenticated-orcid":false,"given":"Kun-Ta","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan."},{"name":"Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan."},{"name":"Center of Sleep Medicine, Taipei Veterans General Hospital, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5218-716X","authenticated-orcid":false,"given":"Chia-Chen","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Taipei Veterans General Hospital, Taipei, Taiwan."},{"name":"Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2022]]},"reference":[{"key":"10.4168\/aair.2022.14.3.314_ref1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/resp.14036","volume":"26","author":"Leong","year":"2021","journal-title":"Respirology"},{"key":"10.4168\/aair.2022.14.3.314_ref2","doi-asserted-by":"crossref","first-page":"180057","DOI":"10.1183\/16000617.0057-2018","volume":"27","author":"Rabe","year":"2018","journal-title":"Eur Respir Rev"},{"key":"10.4168\/aair.2022.14.3.314_ref3","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.chest.2021.01.039","volume":"159","author":"Tan","year":"2021","journal-title":"Chest"},{"key":"10.4168\/aair.2022.14.3.314_ref4","doi-asserted-by":"crossref","first-page":"4415","DOI":"10.1093\/eurheartj\/ehaa793","volume":"41","author":"Yang","year":"2020","journal-title":"Eur Heart J"},{"key":"10.4168\/aair.2022.14.3.314_ref5","first-page":"CD003566","volume":"2005","author":"Salpeter","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"10.4168\/aair.2022.14.3.314_ref6","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1136\/heartjnl-2016-309458","volume":"102","author":"Lipworth","year":"2016","journal-title":"Heart"},{"key":"10.4168\/aair.2022.14.3.314_ref7","unstructured":"Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (2021 report) [Internet]. place unknown. Global Initiative for Chronic Obstructive Lung Disease. 2021. cited 2022 Feb 25. Available from: https:\/\/goldcopd.org\/2021-gold-reports\/"},{"key":"10.4168\/aair.2022.14.3.314_ref8","volume-title":"Global strategy for asthma management and prevention","author":"Global Initiative for Asthma","year":"2021"},{"key":"10.4168\/aair.2022.14.3.314_ref9","doi-asserted-by":"crossref","first-page":"715","DOI":"10.7326\/0003-4819-137-9-200211050-00035","volume":"137","author":"Salpeter","year":"2002","journal-title":"Ann Intern Med"},{"key":"10.4168\/aair.2022.14.3.314_ref10","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1378\/chest.95.3.544","volume":"95","author":"Kaufman","year":"1989","journal-title":"Chest"},{"key":"10.4168\/aair.2022.14.3.314_ref11","doi-asserted-by":"crossref","first-page":"32877","DOI":"10.1074\/jbc.R110.215491","volume":"286","author":"Valverde","year":"2011","journal-title":"J Biol Chem"},{"key":"10.4168\/aair.2022.14.3.314_ref12","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1186\/s12931-019-1198-4","volume":"20","author":"Hosseini","year":"2019","journal-title":"Respir Res"},{"key":"10.4168\/aair.2022.14.3.314_ref13","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1016\/j.jaip.2018.01.035","volume":"6","author":"Su","year":"2018","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.4168\/aair.2022.14.3.314_ref14","doi-asserted-by":"crossref","first-page":"e000470","DOI":"10.1136\/bmjresp-2019-000470","volume":"7","author":"Ingebrigtsen","year":"2020","journal-title":"BMJ Open Respir Res"},{"key":"10.4168\/aair.2022.14.3.314_ref15","doi-asserted-by":"crossref","first-page":"3650","DOI":"10.18632\/aging.102004","volume":"11","author":"Su","year":"2019","journal-title":"Aging (Albany NY)"},{"key":"10.4168\/aair.2022.14.3.314_ref16","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1503\/cmaj.131547","volume":"186","author":"Su","year":"2014","journal-title":"CMAJ"},{"key":"10.4168\/aair.2022.14.3.314_ref17","doi-asserted-by":"crossref","first-page":"e2352","DOI":"10.1097\/MD.0000000000002352","volume":"95","author":"Su","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"10.4168\/aair.2022.14.3.314_ref18","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.chest.2017.04.170","volume":"152","author":"Su","year":"2017","journal-title":"Chest"},{"key":"10.4168\/aair.2022.14.3.314_ref19","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1183\/13993003.00436-2016","volume":"48","author":"Sin","year":"2016","journal-title":"Eur Respir J"},{"key":"10.4168\/aair.2022.14.3.314_ref20","doi-asserted-by":"crossref","first-page":"1700068","DOI":"10.1183\/13993003.00068-2017","volume":"49","author":"Miravitlles","year":"2017","journal-title":"Eur Respir J"},{"key":"10.4168\/aair.2022.14.3.314_ref21","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0895-4356(92)90133-8","volume":"45","author":"Deyo","year":"1992","journal-title":"J Clin Epidemiol"},{"key":"10.4168\/aair.2022.14.3.314_ref22","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1177\/030006051204000602","volume":"40","author":"Ni","year":"2012","journal-title":"J Int Med Res"},{"key":"10.4168\/aair.2022.14.3.314_ref23","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1513\/pats.2306025","volume":"1","author":"Grootendorst","year":"2004","journal-title":"Proc Am Thorac Soc"},{"key":"10.4168\/aair.2022.14.3.314_ref24","first-page":"141","volume":"40","author":"Woo","year":"1995","journal-title":"Br J Clin Pharmacol"},{"key":"10.4168\/aair.2022.14.3.314_ref25","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1365-2125.1995.tb04447.x","volume":"39","author":"Wood","year":"1995","journal-title":"Br J Clin Pharmacol"},{"key":"10.4168\/aair.2022.14.3.314_ref26","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1097\/00000542-200104000-00024","volume":"94","author":"Yamakage","year":"2001","journal-title":"Anesthesiology"},{"key":"10.4168\/aair.2022.14.3.314_ref27","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1159\/000138024","volume":"29","author":"Chapman","year":"1984","journal-title":"Pharmacology"},{"key":"10.4168\/aair.2022.14.3.314_ref28","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/bja\/aeg118","volume":"90","author":"Hirota","year":"2003","journal-title":"Br J Anaesth"}],"container-title":["Allergy, Asthma &amp; Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/e-aair.org\/pdf\/10.4168\/aair.2022.14.3.314","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2022.14.3.314","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2022.14.3.314","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,13]],"date-time":"2022-05-13T07:04:54Z","timestamp":1652425494000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2022.14.3.314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":28,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4168\/aair.2022.14.3.314","relation":{},"ISSN":["2092-7355","2092-7363"],"issn-type":[{"value":"2092-7355","type":"print"},{"value":"2092-7363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"2021-12-12","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-04","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-14","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-06","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2022 The Korean Academy of Asthma, Allergy and Clinical Immunology \u2022 The Korean Academy of Pediatric Allergy and Respiratory Disease","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}