{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T20:53:48Z","timestamp":1789678428634,"version":"4.0.1"},"reference-count":46,"publisher":"XMLink","issue":"5","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003562","name":"Ministry of Environment","doi-asserted-by":"publisher","award":["2017001360006"],"award-info":[{"award-number":["2017001360006"]}],"id":[{"id":"10.13039\/501100003562","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["e-aair.org"],"crossmark-restriction":false},"short-container-title":["Allergy Asthma Immunol Res"],"DOI":"10.4168\/aair.2022.14.5.549","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T04:43:23Z","timestamp":1664340203000},"page":"549","update-policy":"https:\/\/doi.org\/10.4168\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["<i>Bifidobacterium longum<\/i> and Galactooligosaccharide Improve Skin Barrier Dysfunction and Atopic Dermatitis-like Skin"],"prefix":"10.4168","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3204-1398","authenticated-orcid":false,"given":"Sukyung","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Hallym University Dongtan Sacred Heart Hospital, Hallym University School of Medicine, Hwaseong, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8274-5433","authenticated-orcid":false,"given":"Song-Yi","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4571-2506","authenticated-orcid":false,"given":"Jinyoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9255-4144","authenticated-orcid":false,"given":"Na-Rae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7718-1159","authenticated-orcid":false,"given":"Bo Ra","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3323-9347","authenticated-orcid":false,"given":"Hyunmi","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5740-7157","authenticated-orcid":false,"given":"Mijeoung","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7751-9829","authenticated-orcid":false,"given":"Kangmo","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1181-4099","authenticated-orcid":false,"given":"Youngbae","family":"Noh","sequence":"additional","affiliation":[{"name":"Dairyteam, Lotte R&D Center, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0281-3577","authenticated-orcid":false,"given":"Sang Jong","family":"Kim","sequence":"additional","affiliation":[{"name":"Dairyteam, Lotte R&D Center, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6700-2084","authenticated-orcid":false,"given":"Phyrim","family":"Lee","sequence":"additional","affiliation":[{"name":"Dairyteam, Lotte R&D Center, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5379-5853","authenticated-orcid":false,"given":"Dongki","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Translational Research and Cellular Therapeutics, Beckman Research Institute of City of Hope, Duarte, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4923-1814","authenticated-orcid":false,"given":"Byung Eui","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."},{"name":"Department of Pediatrics, National Jewish Health, Denver, CO, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8493-2881","authenticated-orcid":false,"given":"Jihyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2022]]},"reference":[{"key":"10.4168\/aair.2022.14.5.549_ref1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.coi.2020.02.007","volume":"66","author":"Ahn","year":"2020","journal-title":"Curr Opin Immunol"},{"key":"10.4168\/aair.2022.14.5.549_ref2","doi-asserted-by":"crossref","first-page":"84","DOI":"10.2500\/aap.2019.40.4202","volume":"40","author":"Kim","year":"2019","journal-title":"Allergy Asthma Proc"},{"key":"10.4168\/aair.2022.14.5.549_ref3","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.alit.2019.08.013","volume":"69","author":"Sugita","year":"2020","journal-title":"Allergol Int"},{"key":"10.4168\/aair.2022.14.5.549_ref4","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.3390\/ijms17071147","volume":"17","author":"Chan","year":"2016","journal-title":"Int J Mol Sci"},{"key":"10.4168\/aair.2022.14.5.549_ref5","doi-asserted-by":"crossref","first-page":"755","DOI":"10.3920\/BM2017.0034","volume":"8","author":"Kim","year":"2017","journal-title":"Benef Microbes"},{"key":"10.4168\/aair.2022.14.5.549_ref6","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/pai.12010","volume":"23","author":"Han","year":"2012","journal-title":"Pediatr Allergy Immunol"},{"key":"10.4168\/aair.2022.14.5.549_ref7","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3390\/foods8030092","volume":"8","author":"Davani-Davari","year":"2019","journal-title":"Foods"},{"key":"10.4168\/aair.2022.14.5.549_ref8","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1172\/JCI124608","volume":"129","author":"Goleva","year":"2019","journal-title":"J Clin Invest"},{"key":"10.4168\/aair.2022.14.5.549_ref9","doi-asserted-by":"crossref","first-page":"e145185","DOI":"10.1172\/jci.insight.145185","volume":"6","author":"Kim","year":"2018","journal-title":"JCI Insight"},{"key":"10.4168\/aair.2022.14.5.549_ref10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.alit.2017.10.002","volume":"67","author":"Egawa","year":"2018","journal-title":"Allergol Int"},{"key":"10.4168\/aair.2022.14.5.549_ref11","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2332\/allergolint.13-RAI-0564","volume":"62","author":"Leung","year":"2013","journal-title":"Allergol Int"},{"key":"10.4168\/aair.2022.14.5.549_ref12","doi-asserted-by":"crossref","first-page":"3306","DOI":"10.3390\/ijms20133306","volume":"20","author":"Yang","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.4168\/aair.2022.14.5.549_ref13","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.4014\/jmb.1812.12002","volume":"29","author":"Choi","year":"2019","journal-title":"J Microbiol Biotechnol"},{"key":"10.4168\/aair.2022.14.5.549_ref14","doi-asserted-by":"crossref","first-page":"444","DOI":"10.3390\/jcm8040444","volume":"8","author":"Kim","year":"2019","journal-title":"J Clin Med"},{"key":"10.4168\/aair.2022.14.5.549_ref15","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.alit.2017.06.008","volume":"66","author":"Hirata","year":"2017","journal-title":"Allergol Int"},{"key":"10.4168\/aair.2022.14.5.549_ref16","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.4014\/jmb.2005.05017","volume":"30","author":"Kim","year":"2020","journal-title":"J Microbiol Biotechnol"},{"key":"10.4168\/aair.2022.14.5.549_ref17","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1001\/jamapediatrics.2015.3943","volume":"170","author":"Chang","year":"2016","journal-title":"JAMA Pediatr"},{"key":"10.4168\/aair.2022.14.5.549_ref18","doi-asserted-by":"crossref","first-page":"430","DOI":"10.5009\/gnl18316","volume":"13","author":"Zhou","year":"2019","journal-title":"Gut Liver"},{"key":"10.4168\/aair.2022.14.5.549_ref19","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.jaci.2015.08.016","volume":"137","author":"Kim","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2022.14.5.549_ref20","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.4049\/jimmunol.171.6.3262","volume":"171","author":"Nomura","year":"2003","journal-title":"J Immunol"},{"key":"10.4168\/aair.2022.14.5.549_ref21","doi-asserted-by":"crossref","first-page":"e0217194","DOI":"10.1371\/journal.pone.0217194","volume":"14","author":"Choi","year":"2019","journal-title":"PLoS One"},{"key":"10.4168\/aair.2022.14.5.549_ref22","doi-asserted-by":"crossref","first-page":"e2584","DOI":"10.7717\/peerj.2584","volume":"4","author":"Rognes","year":"2016","journal-title":"PeerJ"},{"key":"10.4168\/aair.2022.14.5.549_ref23","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1093\/bioinformatics\/btr381","volume":"27","author":"Edgar","year":"2011","journal-title":"Bioinformatics"},{"key":"10.4168\/aair.2022.14.5.549_ref24","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.jid.2019.07.703","volume":"140","author":"Su","year":"2020","journal-title":"J Invest Dermatol"},{"key":"10.4168\/aair.2022.14.5.549_ref25","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3390\/nu12010249","volume":"12","author":"Kim","year":"2020","journal-title":"Nutrients"},{"key":"10.4168\/aair.2022.14.5.549_ref26","doi-asserted-by":"crossref","first-page":"173020","DOI":"10.1016\/j.ejphar.2020.173020","volume":"874","author":"Bai","year":"2020","journal-title":"Eur J Pharmacol"},{"key":"10.4168\/aair.2022.14.5.549_ref27","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1089\/jmf.2021.K.0032","volume":"24","author":"Kim","year":"2021","journal-title":"J Med Food"},{"key":"10.4168\/aair.2022.14.5.549_ref28","doi-asserted-by":"crossref","first-page":"207","DOI":"10.4168\/aair.2018.10.3.207","volume":"10","author":"Kim","year":"2018","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2022.14.5.549_ref29","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/exd.13130","volume":"26","author":"Sz\u00f6ll\u0151si","year":"2017","journal-title":"Exp Dermatol"},{"key":"10.4168\/aair.2022.14.5.549_ref30","doi-asserted-by":"crossref","first-page":"4887","DOI":"10.1128\/AEM.00982-13","volume":"79","author":"Sultana","year":"2013","journal-title":"Appl Environ Microbiol"},{"key":"10.4168\/aair.2022.14.5.549_ref31","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.3389\/fimmu.2018.01364","volume":"9","author":"Komai","year":"2018","journal-title":"Front Immunol"},{"key":"10.4168\/aair.2022.14.5.549_ref32","doi-asserted-by":"crossref","first-page":"3665","DOI":"10.4049\/jimmunol.1402898","volume":"195","author":"Hsu","year":"2015","journal-title":"J Immunol"},{"key":"10.4168\/aair.2022.14.5.549_ref33","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.clnu.2019.04.004","volume":"39","author":"Kazemi","year":"2020","journal-title":"Clin Nutr"},{"key":"10.4168\/aair.2022.14.5.549_ref34","doi-asserted-by":"crossref","first-page":"3972","DOI":"10.1038\/s41598-021-83252-7","volume":"11","author":"Hofeld","year":"2021","journal-title":"Sci Rep"},{"key":"10.4168\/aair.2022.14.5.549_ref35","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1111\/j.1365-2249.2007.03434.x","volume":"149","author":"Lorea Baroja","year":"2007","journal-title":"Clin Exp Immunol"},{"key":"10.4168\/aair.2022.14.5.549_ref36","doi-asserted-by":"crossref","first-page":"833","DOI":"10.3920\/BM2017.0011","volume":"8","author":"Prakoeswa","year":"2017","journal-title":"Benef Microbes"},{"key":"10.4168\/aair.2022.14.5.549_ref37","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/imm.12791","volume":"152","author":"Ali","year":"2017","journal-title":"Immunology"},{"key":"10.4168\/aair.2022.14.5.549_ref38","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.3389\/fimmu.2017.01628","volume":"8","author":"Bieber","year":"2017","journal-title":"Front Immunol"},{"key":"10.4168\/aair.2022.14.5.549_ref39","doi-asserted-by":"crossref","first-page":"836","DOI":"10.3390\/microorganisms9040836","volume":"9","author":"Marras","year":"2021","journal-title":"Microorganisms"},{"key":"10.4168\/aair.2022.14.5.549_ref40","doi-asserted-by":"crossref","first-page":"516","DOI":"10.4168\/aair.2018.10.5.516","volume":"10","author":"Kim","year":"2018","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2022.14.5.549_ref41","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1002\/smll.201401803","volume":"11","author":"Jang","year":"2015","journal-title":"Small"},{"key":"10.4168\/aair.2022.14.5.549_ref42","doi-asserted-by":"crossref","first-page":"8899","DOI":"10.3390\/ijms21238899","volume":"21","author":"Haas-Neill","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.4168\/aair.2022.14.5.549_ref43","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1038\/s41422-020-0332-7","volume":"30","author":"Zheng","year":"2020","journal-title":"Cell Res"},{"key":"10.4168\/aair.2022.14.5.549_ref44","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.immuni.2018.07.016","volume":"49","author":"Price","year":"2018","journal-title":"Immunity"},{"key":"10.4168\/aair.2022.14.5.549_ref45","first-page":"57","volume":"21","author":"Ahmadi Badi","year":"2019","journal-title":"Cell J"},{"key":"10.4168\/aair.2022.14.5.549_ref46","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.3390\/nu11051038","volume":"11","author":"Molina-Tijeras","year":"2019","journal-title":"Nutrients"}],"container-title":["Allergy, Asthma &amp; Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/e-aair.org\/pdf\/10.4168\/aair.2022.14.5.549","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2022.14.5.549","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2022.14.5.549","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T04:50:01Z","timestamp":1664340601000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2022.14.5.549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":46,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4168\/aair.2022.14.5.549","relation":{},"ISSN":["2092-7355","2092-7363"],"issn-type":[{"value":"2092-7355","type":"print"},{"value":"2092-7363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"2022-04-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-30","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-05","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-16","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2022 The Korean Academy of Asthma, Allergy and Clinical Immunology \u2022 The Korean Academy of Pediatric Allergy and Respiratory Disease","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}