{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:45:26Z","timestamp":1788777926826,"version":"build-2803163510"},"reference-count":53,"publisher":"XMLink","issue":"5","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Korean Academy of Pediatric Allergy and Respiratory Disease","award":["HR22C1605030022"],"award-info":[{"award-number":["HR22C1605030022"]}]},{"name":"Chonnam National University Hospital Biomedical Research Institute","award":["BCRI-24082"],"award-info":[{"award-number":["BCRI-24082"]}]}],"content-domain":{"domain":["e-aair.org"],"crossmark-restriction":false},"short-container-title":["Allergy Asthma Immunol Res"],"DOI":"10.4168\/aair.2024.16.5.490","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T06:50:45Z","timestamp":1727679045000},"page":"490","update-policy":"https:\/\/doi.org\/10.4168\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of Wheezing Requiring Hospitalization Before 2 Years of Age With Autoimmune Diseases During Childhood: A 15-Year Follow-up Study From Birth"],"prefix":"10.4168","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7462-0144","authenticated-orcid":false,"given":"Eun","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4945-0753","authenticated-orcid":false,"given":"Ju Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8863-5729","authenticated-orcid":false,"given":"Eun Kyo","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5179-4013","authenticated-orcid":false,"given":"Jeewon","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Ilsan CHA Medical Center, CHA University School of Medicine, Goyang, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1065-390X","authenticated-orcid":false,"given":"Bo Eun","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Bundang CHA Medical Center, CHA University School of Medicine, Seongnam, Korea."},{"name":"Multi-omics Research Center, CHA Future Medicine Research Institute, Seongnam, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0297-9446","authenticated-orcid":false,"given":"Hey Sung","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9077-5779","authenticated-orcid":false,"given":"Man Yong","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Bundang CHA Medical Center, CHA University School of Medicine, Seongnam, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2024]]},"reference":[{"key":"10.4168\/aair.2024.16.5.490_ref1","doi-asserted-by":"crossref","first-page":"1028525","DOI":"10.3389\/fpubh.2022.1028525","volume":"10","author":"Safiri","year":"2023","journal-title":"Front Public Health"},{"key":"10.4168\/aair.2024.16.5.490_ref2","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S0140-6736(22)01016-9","volume":"400","author":"Dalziel","year":"2022","journal-title":"Lancet"},{"key":"10.4168\/aair.2024.16.5.490_ref3","doi-asserted-by":"crossref","first-page":"218","DOI":"10.3389\/fped.2020.00218","volume":"8","author":"Douros","year":"2020","journal-title":"Front Pediatr"},{"key":"10.4168\/aair.2024.16.5.490_ref4","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/apa.16099","volume":"111","author":"Ruotsalainen","year":"2022","journal-title":"Acta Paediatr"},{"key":"10.4168\/aair.2024.16.5.490_ref5","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3345\/cep.2021.01746","volume":"65","author":"Chung","year":"2022","journal-title":"Clin Exp Pediatr"},{"key":"10.4168\/aair.2024.16.5.490_ref6","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/j.jaci.2021.08.035","volume":"149","author":"Dumas","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2024.16.5.490_ref7","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1093\/infdis\/jiad093","volume":"228","author":"Mu\u00f1oz-Quiles","year":"2023","journal-title":"J Infect Dis"},{"issue":"Suppl 2","key":"10.4168\/aair.2024.16.5.490_ref8","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1186\/ar1703","volume":"7","author":"Skapenko","year":"2005","journal-title":"Arthritis Res Ther"},{"key":"10.4168\/aair.2024.16.5.490_ref9","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3345\/cep.2023.00605","volume":"66","author":"Kim","year":"2023","journal-title":"Clin Exp Pediatr"},{"key":"10.4168\/aair.2024.16.5.490_ref10","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1586\/1744666X.4.6.767","volume":"4","author":"Tedeschi","year":"2008","journal-title":"Expert Rev Clin Immunol"},{"key":"10.4168\/aair.2024.16.5.490_ref11","doi-asserted-by":"crossref","first-page":"e200834","DOI":"10.1001\/jamanetworkopen.2020.0834","volume":"3","author":"Smew","year":"2020","journal-title":"JAMA Netw Open"},{"key":"10.4168\/aair.2024.16.5.490_ref12","doi-asserted-by":"crossref","first-page":"428","DOI":"10.4168\/aair.2018.10.5.428","volume":"10","author":"Mukherjee","year":"2018","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.4168\/aair.2024.16.5.490_ref13","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1164\/rccm.202211-2074ED","volume":"207","author":"Murphy","year":"2023","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2024.16.5.490_ref14","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/s12020-021-02973-x","volume":"75","author":"Zeng","year":"2022","journal-title":"Endocrine"},{"key":"10.4168\/aair.2024.16.5.490_ref15","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.mayocp.2012.05.020","volume":"87","author":"Yun","year":"2012","journal-title":"Mayo Clin Proc"},{"key":"10.4168\/aair.2024.16.5.490_ref16","doi-asserted-by":"crossref","first-page":"21728","DOI":"10.1038\/s41598-022-26067-4","volume":"12","author":"Liljendahl","year":"2022","journal-title":"Sci Rep"},{"key":"10.4168\/aair.2024.16.5.490_ref17","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1002\/pds.2233","volume":"21","author":"Karlstad","year":"2012","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.4168\/aair.2024.16.5.490_ref18","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.anai.2023.05.035","volume":"131","author":"Lee","year":"2023","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.4168\/aair.2024.16.5.490_ref19","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1164\/rccm.200410-1404OC","volume":"171","author":"Saglani","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2024.16.5.490_ref20","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/all.13624","volume":"74","author":"Jartti","year":"2019","journal-title":"Allergy"},{"key":"10.4168\/aair.2024.16.5.490_ref21","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1111\/all.14154","volume":"75","author":"Manti","year":"2020","journal-title":"Allergy"},{"key":"10.4168\/aair.2024.16.5.490_ref22","doi-asserted-by":"crossref","first-page":"e2026","DOI":"10.1002\/rmv.2026","volume":"29","author":"Tahamtan","year":"2019","journal-title":"Rev Med Virol"},{"issue":"Suppl 22","key":"10.4168\/aair.2024.16.5.490_ref23","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/pedi.12341","volume":"17","author":"Virtanen","year":"2016","journal-title":"Pediatr Diabetes"},{"key":"10.4168\/aair.2024.16.5.490_ref24","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/gene.2008.100","volume":"10","author":"Bj\u00f8rnvold","year":"2009","journal-title":"Genes Immun"},{"key":"10.4168\/aair.2024.16.5.490_ref25","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1056\/NEJMoa0906312","volume":"363","author":"Moffatt","year":"2010","journal-title":"N Engl J Med"},{"key":"10.4168\/aair.2024.16.5.490_ref26","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/ng.381","volume":"41","author":"Barrett","year":"2009","journal-title":"Nat Genet"},{"key":"10.4168\/aair.2024.16.5.490_ref27","doi-asserted-by":"crossref","first-page":"e002055","DOI":"10.1136\/rmdopen-2021-002055","volume":"8","author":"Adami","year":"2022","journal-title":"RMD Open"},{"key":"10.4168\/aair.2024.16.5.490_ref28","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1398-9995.2007.01586.x","volume":"63","author":"Bacharier","year":"2008","journal-title":"Allergy"},{"key":"10.4168\/aair.2024.16.5.490_ref29","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1136\/thoraxjnl-2020-216109","volume":"76","author":"Wang","year":"2021","journal-title":"Thorax"},{"key":"10.4168\/aair.2024.16.5.490_ref30","doi-asserted-by":"crossref","first-page":"638470","DOI":"10.1155\/2015\/638470","volume":"2015","author":"Li","year":"2015","journal-title":"Mediators Inflamm"},{"key":"10.4168\/aair.2024.16.5.490_ref31","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.cyto.2006.04.015","volume":"34","author":"Kainonen","year":"2006","journal-title":"Cytokine"},{"key":"10.4168\/aair.2024.16.5.490_ref32","doi-asserted-by":"crossref","first-page":"2035117","DOI":"10.1080\/21645515.2022.2035117","volume":"18","author":"Goswami","year":"2022","journal-title":"Hum Vaccin Immunother"},{"key":"10.4168\/aair.2024.16.5.490_ref33","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1172\/JCI200423595","volume":"114","author":"Robinson","year":"2004","journal-title":"J Clin Invest"},{"key":"10.4168\/aair.2024.16.5.490_ref34","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/s41577-021-00538-7","volume":"21","author":"Akdis","year":"2021","journal-title":"Nat Rev Immunol"},{"key":"10.4168\/aair.2024.16.5.490_ref35","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/s41577-022-00727-y","volume":"23","author":"Miyauchi","year":"2023","journal-title":"Nat Rev Immunol"},{"key":"10.4168\/aair.2024.16.5.490_ref36","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1164\/rccm.202003-0634ED","volume":"202","author":"Wark","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"10.4168\/aair.2024.16.5.490_ref37","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1159\/000486899","volume":"96","author":"Nasser","year":"2018","journal-title":"Respiration"},{"key":"10.4168\/aair.2024.16.5.490_ref38","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1038\/labinvest.2015.72","volume":"95","author":"Guest","year":"2015","journal-title":"Lab Invest"},{"key":"10.4168\/aair.2024.16.5.490_ref39","doi-asserted-by":"crossref","first-page":"e2147363","DOI":"10.1001\/jamanetworkopen.2021.47363","volume":"5","author":"Kang","year":"2022","journal-title":"JAMA Netw Open"},{"key":"10.4168\/aair.2024.16.5.490_ref40","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/s41584-020-0426-0","volume":"16","author":"Noval Rivas","year":"2020","journal-title":"Nat Rev Rheumatol"},{"key":"10.4168\/aair.2024.16.5.490_ref41","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.coi.2017.08.008","volume":"48","author":"Guttman-Yassky","year":"2017","journal-title":"Curr Opin Immunol"},{"key":"10.4168\/aair.2024.16.5.490_ref42","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.alit.2023.12.005","volume":"73","author":"Ahn","year":"2024","journal-title":"Allergol Int"},{"key":"10.4168\/aair.2024.16.5.490_ref43","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1111\/bjd.13518","volume":"172","author":"Fang","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.4168\/aair.2024.16.5.490_ref44","doi-asserted-by":"crossref","first-page":"e116077","DOI":"10.1371\/journal.pone.0116077","volume":"9","author":"Kao","year":"2014","journal-title":"PLoS One"},{"key":"10.4168\/aair.2024.16.5.490_ref45","doi-asserted-by":"crossref","first-page":"3140682","DOI":"10.1155\/2018\/3140682","volume":"2018","author":"Santus","year":"2018","journal-title":"BioMed Res Int"},{"key":"10.4168\/aair.2024.16.5.490_ref46","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.jaci.2022.03.030","volume":"150","author":"de Lusignan","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2024.16.5.490_ref47","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/all.15917","volume":"79","author":"Kim","year":"2024","journal-title":"Allergy"},{"key":"10.4168\/aair.2024.16.5.490_ref48","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1038\/ng.2642","volume":"45","author":"Ellinghaus","year":"2013","journal-title":"Nat Genet"},{"key":"10.4168\/aair.2024.16.5.490_ref49","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.jaci.2004.06.038","volume":"114","author":"Heinzmann","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.4168\/aair.2024.16.5.490_ref50","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s12969-016-0074-8","volume":"14","author":"Lin","year":"2016","journal-title":"Pediatr Rheumatol Online J"},{"key":"10.4168\/aair.2024.16.5.490_ref51","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1093\/ije\/dyac193","volume":"52","author":"Lewis","year":"2023","journal-title":"Int J Epidemiol"},{"key":"10.4168\/aair.2024.16.5.490_ref52","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1136\/thx.2009.121582","volume":"65","author":"Sigurs","year":"2010","journal-title":"Thorax"},{"key":"10.4168\/aair.2024.16.5.490_ref53","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/s41581-023-00720-1","volume":"19","author":"Pisetsky","year":"2023","journal-title":"Nat Rev Nephrol"}],"container-title":["Allergy, Asthma & Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/e-aair.org\/pdf\/10.4168\/aair.2024.16.5.490","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2024.16.5.490","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2024.16.5.490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T06:55:16Z","timestamp":1727679316000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-aair.org\/DOIx.php?id=10.4168\/aair.2024.16.5.490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":53,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4168\/aair.2024.16.5.490","relation":{},"ISSN":["2092-7355","2092-7363"],"issn-type":[{"value":"2092-7355","type":"print"},{"value":"2092-7363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"2023-12-13","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-22","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-17","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-27","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2024 The Korean Academy of Asthma, Allergy and Clinical Immunology \u2022 The Korean Academy of Pediatric Allergy and Respiratory Disease","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}