{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:27:11Z","timestamp":1792160831188,"version":"4.4.0"},"reference-count":30,"publisher":"Asian Spine Journal (ASJ)","issue":"2","license":[{"start":{"date-parts":[[2017,4,12]],"date-time":"2017-04-12T00:00:00Z","timestamp":1491955200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["asianspinejournal.org"],"crossmark-restriction":true},"short-container-title":["Asian Spine J"],"published-print":{"date-parts":[[2017,4,30]]},"abstract":"<sec><title>Study Design<\/title><p>Retrospective review of prospective registry data.<\/p><\/sec><sec><title>Purpose<\/title><p>To determine 5-year clinical and radiological outcomes of single-level instrumented minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in patients with neurogenic symptoms secondary to spondylolisthesis.<\/p><\/sec><sec><title>Overview of Literature<\/title><p>MIS-TLIF and open approaches have been shown to yield comparable outcomes. This is the first study to assess MIS-TLIF outcomes using the minimal clinically important difference (MCID) criterion.<\/p><\/sec><sec><title>Methods<\/title><p>The outcomes of 56 patients treated by a single surgeon, including the Oswestry disability index (ODI), neurogenic symptom score, short-form 36 questionnaire (SF-36), and visual analog scale (VAS) scores for back pain (BP), and leg pain (LP), were collected prospectively for up to 5 years postoperatively. Radiological outcomes included adjacent segment degeneration, fusion, cage subsidence, and screw loosening rates.<\/p><\/sec><sec><title>Results<\/title><p>Our patients were predominantly female (71.4%) and had a mean age of 53.7\u00b111.3 years and mean body mass index of 25.7\u00b13.7 kg\/m<sup>2<\/sup>. The mean operative time, blood loss, time to ambulation, and hospitalization were 167\u00b149 minutes, 126\u00b1107 mL, 1.2\u00b10.4 days, and 2.8\u00b11.1 days, respectively. The mean fluoroscopic time was 58.4\u00b133 seconds, and the mean postoperative intravenous morphine dose was 8\u00b12 mg. Regarding outcomes, postoperative scores improved relative to preoperative scores, and this was sustained across various time points for up to 5 years (<italic>p<\/italic>&lt;0.001). Improvements in ODI, SF-36, VAS-BP, and VAS-LP all met the MCID criterion. Notably, 5.4% of our patients developed clinically significant adjacent segment disease during follow-up, and 7 minor complications were reported.<\/p><\/sec><sec><title>Conclusions<\/title><p>Single-level instrumented MIS-TLIF is suitable for patients with neurogenic symptoms secondary to lumbar spondylolisthesis and is associated with an acceptable complication rate. Both clinical and radiological outcomes were sustained up to 5 years postoperatively, with many patients achieving an MCID.<\/p><\/sec><\/jats:p>","DOI":"10.4184\/asj.2017.11.2.204","type":"journal-article","created":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T08:03:46Z","timestamp":1492761826000},"page":"204-212","update-policy":"https:\/\/doi.org\/10.31616\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Single-Level Minimally Invasive Transforaminal Lumbar Interbody Fusion Provides Sustained Improvements in Clinical and Radiological Outcomes up to 5 Years Postoperatively in Patients with Neurogenic Symptoms Secondary to Spondylolisthesis"],"prefix":"10.31616","volume":"11","author":[{"given":"Hamid Rahmatullah","family":"Bin Abd 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