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Chest x-ray revealed areas of parenchymal consolidation and high-resolution computed tomography demonstrated a pulmonary nodular pattern with no lymph node enlargement. All laboratory and pulmonary function tests were normal. Bronchoscopy with bronchoalveolar lavage showed no sign of infection or specific inflammation. The diagnosis of NSG was made by histopathological examination of a surgical lung biopsy and by excluding other causes of granulomatous disease. In paucisymptomatic\/asymptomatic patients, as in our case, therapy is not necessary, with a good prognosis and complete recovery. NSG is a rare systemic disease similar to sarcoidosis and Wegener's granulomatosis with a benign clinical course and should always be considered for patients with nodular pulmonary lesions even with subclinical or uncommon features.<\/jats:p>","DOI":"10.4187\/respcare.02842","type":"journal-article","created":{"date-parts":[[2013,12,10]],"date-time":"2013-12-10T23:05:19Z","timestamp":1386716719000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Necrotizing Sarcoid Granulomatosis With an Uncommon Manifestation: Clinicopathological Features and Review of Literature"],"prefix":"10.1177","volume":"59","author":[{"given":"Chiara","family":"Giraudo","sequence":"first","affiliation":[{"name":"Department of Radiology, Venetian Oncology Institute, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazarena","family":"Nannini","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Balestro","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"Meneghin","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hospital of Montebelluna, Treviso, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Lunardi","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Polverosi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Venetian Oncology Institute, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiorella","family":"Calabrese","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,12,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00024205"},{"issue":"1","key":"e_1_3_3_3_2","first-page":"1","article-title":"The J. 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