{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T04:49:47Z","timestamp":1780375787154,"version":"3.54.1"},"reference-count":41,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2014,6,3]],"date-time":"2014-06-03T00:00:00Z","timestamp":1401753600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Noninvasive ventilation (NIV) has been recognized as an effective strategy in preventing endotracheal intubation in subjects with acute respiratory failure (ARF). Some interface-related complications have also been recognized, such as skin breakdown (SB). The aim of this study was to determine the frequency of SB and identify potential treatment-related risk factors for its development in adults with ARF undergoing NIV or CPAP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>A cross-sectional study was conducted in a general hospital. Subjects were retrospectively enrolled in this study if they were &gt; 18 y old and developed ARF caused by any condition in which NIV or CPAP was indicated for at least one application for a period longer than 2 h. The outcomes were the prevalence of SB and the evaluation of related risk factors. Data were extracted from the electronic medical records. A stepwise forward logistic regression model was used to identify independent risk factors for SB development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      A total of 375 subjects (160 males) met the inclusion criteria and were enrolled in the study. Fifty-four subjects (14.4%) developed SB. The mean number of applications of NIV or CPAP carried out for &gt; 2 h was higher in subjects with SB (7.1 \u00b1 13.3 h) than in those without SB (4.4 \u00b1 13.3 h) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .03). Subjects with SB also presented a higher total duration of NIV use (44.6 \u00b1 118.5 h) compared with subjects without SB (21.8 \u00b1 45.5 h) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .01). Subjects who developed SB presented a higher use of oronasal mask (92.6%) compared with the group that did not (21.5%) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>In patients with ARF undergoing NIV or CPAP, oronasal mask use for &gt; 26 h was independently associated with development of SB.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.02942","type":"journal-article","created":{"date-parts":[[2014,6,3]],"date-time":"2014-06-03T23:39:00Z","timestamp":1401838740000},"page":"1530-1536","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":52,"title":["Treatment-Related Risk Factors for Development of Skin Breakdown in Subjects With Acute Respiratory Failure Undergoing Noninvasive Ventilation or CPAP"],"prefix":"10.1177","volume":"59","author":[{"given":"Wellington P","family":"Yamaguti","sequence":"first","affiliation":[{"name":"Rehabilitation Service, Physiotherapy Department, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliana V","family":"Moderno","sequence":"additional","affiliation":[{"name":"Rehabilitation Service, Physiotherapy Department, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra Y","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Rehabilitation Service, Physiotherapy Department, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thelma GMC","family":"Gomes","sequence":"additional","affiliation":[{"name":"Rehabilitation Service, Physiotherapy Department, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana L\u00edgia V","family":"Maida","sequence":"additional","affiliation":[{"name":"Rehabilitation Service, Physiotherapy Department, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia S","family":"Kondo","sequence":"additional","affiliation":[{"name":"Rehabilitation Service, Physiotherapy Department, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel CD","family":"de Salles","sequence":"additional","affiliation":[{"name":"Rehabilitation Service, Physiotherapy Department, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina MM","family":"de Brito","sequence":"additional","affiliation":[{"name":"Rehabilitation Service, Physiotherapy Department, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,6,3]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.18.2361"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02323-0"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.7.2101089"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.05500924"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2008.08.001"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199509283331301"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000196361"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000076676"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707992"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000076675"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2012.08.007"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1159\/000088897"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200505-718OC"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-128-9-199805010-00004"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.09540246"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e3181a1f708"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200006000-00015"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-006-0391-3"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.1.ats1000"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1159\/000105163"},{"issue":"7","key":"e_1_3_2_22_2","first-page":"842","article-title":"Sedation during non-invasive ventilation","volume":"78","author":"Hilbert G","year":"2012","unstructured":"Hilbert G, , Clouzeau B, , Nam Bui H, , Vargas F. Sedation during non-invasive ventilation. Minerva Anestesiol, 2012; 78(7):842\u2013846.","journal-title":"Minerva Anestesiol"},{"issue":"10","key":"e_1_3_2_23_2","first-page":"1154","article-title":"Interfaces for noninvasive mechanical ventilation: technical aspects and efficiency","volume":"78","author":"Pisani L","year":"2012","unstructured":"Pisani L, , Carlucci A, , Nava S. Interfaces for noninvasive mechanical ventilation: technical aspects and efficiency. Minerva Anestesiol, 2012; 78(10):1154\u20131161.","journal-title":"Minerva Anestesiol"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-2669-2"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-002-1208-7"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1159\/000324259"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1114\/1.1624602"},{"key":"e_1_3_2_28_2","unstructured":"European Pressure Ulcer Advisory Panel National Pressure Ulcer Advisory Panel. Prevention and treatment of pressure ulcers: quick reference guide. 2009. http:\/\/www.epuap.org\/guidelines\/Final_Quick_Prevention.pdf. Accessed May 14 2014."},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200401000-00007"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-002-1478-0"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2320-7"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.151.6.7767523"},{"issue":"10","key":"e_1_3_2_33_2","first-page":"1146","article-title":"Recent advances in interfaces for non-invasive ventilation: from bench studies to practical issues","volume":"78","author":"Sferrazza Papa GF","year":"2012","unstructured":"Sferrazza Papa GF, , Di Marco F, , Akoumianaki E, , Brochard L. Recent advances in interfaces for non-invasive ventilation: from bench studies to practical issues. Minerva Anestesiol, 2012; 78(10):1146\u20131153.","journal-title":"Minerva Anestesiol"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1159\/000324441"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132009000200010"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.106.4.1109"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.09540071"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31819b575f"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0b013e3182514c50"},{"issue":"2","key":"e_1_3_2_40_2","first-page":"109","article-title":"Noninvasive positive pressure ventilation in trauma subjects with acute respiratory failure","volume":"54","author":"Beltrame F","year":"1999","unstructured":"Beltrame F, , Lucangelo U, , Gregori D, , Gregoretti C. Noninvasive positive pressure ventilation in trauma subjects with acute respiratory failure. Monaldi Arch Chest Dis, 1999; 54(2):109\u2013114.","journal-title":"Monaldi Arch Chest Dis"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.109.1.179"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.07521463"}],"container-title":["Respiratory Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.4187\/respcare.02942","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.02942","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.02942","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:10:02Z","timestamp":1777615802000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4187\/respcare.02942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,3]]},"references-count":41,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.4187\/respcare.02942"],"URL":"https:\/\/doi.org\/10.4187\/respcare.02942","relation":{},"ISSN":["0020-1324"],"issn-type":[{"value":"0020-1324","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6,3]]}}}