{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:48:57Z","timestamp":1777891737672,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2014,11]]},"abstract":"\n BACKGROUND:<\/jats:title>\n We sought to compare the accuracy of a newly developed childhood asthma score (CAS) with routine clinical assessment of respiratory status in children with acute asthma in predicting requirements for bronchodilator nebulization.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n In this prospective observational study in children 2\u201318 y old with acute asthma, we evaluated the association between the CAS and routine clinical assessment as well as inter-rater agreement.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n \n The need for bronchodilator nebulization was assessed during 134 episodes of acute asthma in 47 children. Overall, bronchodilators were administered after routine clinical assessment in 74 episodes (55.2%). The median CAS was 2.5 (interquartile range of 2.0\u20133.0) for subjects who did not receive nebulization and 6.0 (interquartile range of 4.0\u20137.0) for subjects who did receive nebulization (\n P<\/jats:italic>\n < .001). A CAS cutoff score of 4 yielded a sensitivity of 0.91 (95% CI 0.84\u20130.97) and a specificity of 0.77 (95% CI 0.66\u20130.87), with a positive predictive value of 0.83 (95% CI 0.75\u20130.91) and a negative predictive value of 0.87 (95% CI 0.78\u20130.96). In 79 episodes, the CAS was assessed by 2 independent raters. With a weighted kappa of 0.77, a good inter-rater agreement was obtained.\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n Using a cutoff value of 4, the newly developed CAS accurately predicts the requirement for bronchodilator nebulization in children with acute asthma without use of auscultative findings.<\/jats:p>\n <\/jats:sec>","DOI":"10.4187\/respcare.02991","type":"journal-article","created":{"date-parts":[[2014,8,27]],"date-time":"2014-08-27T02:41:00Z","timestamp":1409107260000},"page":"1710-1715","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["An Innovative Childhood Asthma Score Predicts the Need for Bronchodilator Nebulization in Children With Acute Asthma Independent of Auscultative Findings"],"prefix":"10.1177","volume":"59","author":[{"given":"Arvid WA","family":"Kamps","sequence":"first","affiliation":[{"name":"Department of Paediatrics"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nic JGM","family":"Veeger","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, MCL Academy, Medical Centre Leeuwarden, Leeuwarden, The Netherlands."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigrid M","family":"Heijsman","sequence":"additional","affiliation":[{"name":"Department of Paediatrics"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,11,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(96)00027-3"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2000.110121"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10425"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1197\/aemj.9.2.99"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1197\/j.aem.2003.07.015"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.08.034"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e31818c268f"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)62514-8"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.09.033"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(94)70347-7"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.06.072"},{"key":"e_1_3_3_13_2","volume-title":"Psychometric theory","author":"Nunnally JC","year":"1994","unstructured":"Nunnally JC, , Bernstein IH. Psychometric theory. New York: McGraw-Hill; 1994."},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.106.5.1006"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2011.03.011"}],"container-title":["Respiratory Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.4187\/respcare.02991","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.02991","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.02991","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:10:08Z","timestamp":1777615808000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4187\/respcare.02991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.4187\/respcare.02991"],"URL":"https:\/\/doi.org\/10.4187\/respcare.02991","relation":{},"ISSN":["0020-1324"],"issn-type":[{"value":"0020-1324","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]}}}