{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T03:04:20Z","timestamp":1779937460715,"version":"3.53.1"},"reference-count":33,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2014,6,24]],"date-time":"2014-06-24T00:00:00Z","timestamp":1403568000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>\n                      This study prospectively evaluated the effect of early bronchoalveolar lavage (BAL) on refractory\n                      <jats:italic toggle=\"yes\">Mycoplasma pneumoniae<\/jats:italic>\n                      pneumonia with radiologically proven large pulmonary lesions in children.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      A total of 35 children diagnosed as having refractory\n                      <jats:italic toggle=\"yes\">M. pneumoniae<\/jats:italic>\n                      pneumonia with radiologically proven large pulmonary lesions completed the study. According to the time point of BAL, they were divided into 2 groups. In the early BAL group, BAL was performed within 3 d after admission (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 22); in the late BAL group, BAL was performed 3 d later after admission (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 13). Clinical effects were compared between these 2 groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      After BAL therapy, improvement in clinical symptoms and laboratory findings as well as resolution of pulmonary lesions on radiography were obtained in all subjects. The median fever duration after admission was 4 (2\u20137) d and 5 (2\u201310) d (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05), and the median hospitalization duration was 7 (5\u201310) d and 10 (5\u201314) d (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05), respectively, in the early BAL group and the late BAL group. Approximately 7 d after admission, 67% of subjects in the early BAL group showed resolution of atelectasis on x-ray image versus a corresponding rate of 14% in the late BAL group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05). Furthermore, laboratory indices recovered quicker in the early BAL group than in the late BAL group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>\n                      BAL appeared to be efficacious and well-tolerated treatment for refractory\n                      <jats:italic toggle=\"yes\">M. pneumoniae<\/jats:italic>\n                      pneumonia with radiologically proven large pulmonary lesions, and early application of BAL may be more beneficial.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.03032","type":"journal-article","created":{"date-parts":[[2014,6,24]],"date-time":"2014-06-24T23:34:24Z","timestamp":1403652864000},"page":"1433-1439","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":36,"title":["Effects of Bronchoalveolar Lavage on Refractory\n                    <i>Mycoplasma pneumoniae<\/i>\n                    Pneumonia"],"prefix":"10.1177","volume":"59","author":[{"given":"Yuanyuan","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhimin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunlian","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanjian","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingshuo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,6,24]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.4.701"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2008.06.022"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-0240"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2008.02622.x"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e328341579c"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1413-86702009000100018"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000130074.56368.4b"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/317498"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.40.345"},{"issue":"10","key":"e_1_3_3_11_2","first-page":"745","article-title":"Guidelines for management of community acquired pneumonia in children (the revised edition of 2013) (I)","volume":"51","author":"The Subspecialty Group of Respiratory Disease, The Society of Pediatrics, Chinese Medical Association, The Editorial Board, Chinese Journal of Pediatrics","year":"2013","unstructured":"The Subspecialty Group of Respiratory Disease, The Society of Pediatrics, Chinese Medical Association, The Editorial Board, Chinese Journal of Pediatrics. 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