{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T21:48:24Z","timestamp":1788385704059,"version":"build-2803163510"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T00:00:00Z","timestamp":1414454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Although noninvasive ventilation (NIV) is increasingly used in general wards, limited information exists about its ability to provide effective ventilation in this setting. We aim to evaluate NIV delivered in the ward by assessing (1) overall time of application and occurrence of adverse events and (2) differences between daytime and nighttime NIV application.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>We studied subjects with hypercapnic acute hypercapnic respiratory failure not fulfilling strict criteria for ICU admission, and excluded those who interrupted NIV prior to 48 h. Time spent on NIV, presence and extent of air leaks, and occurrence of desaturations were assessed for the overall study period, and compared between daytime and nighttime.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      We enrolled 42 subjects, 25 of whom received NIV for at least 48 h and were included in the data analysis. NIV was successful for 20 subjects, who did not reach criteria for ICU admission. Both P\n                      <jats:sub>\n                        aCO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      and pH significantly improved on average after 2 h and at the end of the study period. NIV was applied for 64.5% of the overall study period and had absent or compensated air leaks for 62.3% of the overall 48-h period. NIV was applied for 55.8% of daytime and for 79.3% of nighttime (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .01). Effective NIV application was significantly longer overnight (76.9%) than during daytime (53.2%) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>In selected subjects with hypercapnic acute respiratory failure not fulfilling criteria for ICU admission, the application of NIV in the ward is feasible; in addition, NIV can be safely administered overnight.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.03294","type":"journal-article","created":{"date-parts":[[2014,10,29]],"date-time":"2014-10-29T00:29:25Z","timestamp":1414542565000},"page":"6-11","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Does Noninvasive Ventilation Delivery in the Ward Provide Early Effective Ventilation?"],"prefix":"10.1177","volume":"60","author":[{"given":"Carlo","family":"Olivieri","sequence":"first","affiliation":[{"name":"Anesthesia and Intensive Care, Maggiore della Carit\u00e0 University Hospital, Novara"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Carenzo","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine, Universit\u00e0 del Piemonte Orientale Amedeo Avogadro, Novara"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Luca","family":"Vignazia","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care, Maggiore della Carit\u00e0 University Hospital, Novara"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Campanini","sequence":"additional","affiliation":[{"name":"Internal Medicine, Maggiore della Carit\u00e0 University Hospital, Novara"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Pirisi","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine, Universit\u00e0 del Piemonte Orientale Amedeo Avogadro, Novara"},{"name":"Internal Medicine, Maggiore della Carit\u00e0 University Hospital, Novara"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Della Corte","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care, Maggiore della Carit\u00e0 University Hospital, Novara"},{"name":"Department of Translational Medicine, Universit\u00e0 del Piemonte Orientale Amedeo Avogadro, Novara"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Navalesi","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine, Universit\u00e0 del Piemonte Orientale Amedeo Avogadro, Novara"},{"name":"Anesthesia and Intensive Care, Sant'Andrea Hospital, Vercelli; and with CRRF Mons. L. Novarese, Moncrivello, Vercelli, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,10,28]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60496-7"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7382.185"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02323-0"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-0050-0"},{"issue":"24","key":"e_1_3_2_6_2","first-page":"2034","article-title":"Early use of non-invasive positive pressure ventilation for acute exacerbations of chronic obstructive pulmonary disease: a multicentre randomized controlled trial","volume":"118","author":"Collaborative Research Group of Noninvasive Mechanical Ventilation for Chronic Obstructive Pulmonary Disease","year":"2005","unstructured":"Collaborative Research Group of Noninvasive Mechanical Ventilation for Chronic Obstructive Pulmonary Disease. Early use of non-invasive positive pressure ventilation for acute exacerbations of chronic obstructive pulmonary disease: a multicentre randomized controlled trial. Chin Med J (Engl), 2005; 118(24):2034\u20132040.","journal-title":"Chin Med J (Engl)"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-008-1350-y"},{"issue":"7","key":"e_1_3_2_8_2","first-page":"459","article-title":"Non-invasive ventilation outside the intensive care unit for acute respiratory failure","volume":"75","author":"Chiumello D","year":"2009","unstructured":"Chiumello D, , Conti G, , Foti G, , Giacomini MM, , Braschi A, , Iapichino G. Non-invasive ventilation outside the intensive care unit for acute respiratory failure. Minerva Anestesiol, 2009; 75(7-8):459\u2013466.","journal-title":"Minerva Anestesiol"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.03355"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.4.2006027"},{"key":"e_1_3_2_11_2","unstructured":"Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis management and prevention of COPD Updated 2013. Available from: http:\/\/www.goldcopd.org\/Guidelines\/guidelines-resources.html. Accessed September 24 2014."},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00170508"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-006-0229-z"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa012247"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(79)91166-5"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60102-6"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000206116.10417.D9"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.02.00297202"},{"issue":"3","key":"e_1_3_2_19_2","first-page":"313","article-title":"Non-invasive ventilation outside of the intensive care unit: an Italian survey","volume":"77","author":"Cabrini L","year":"2011","unstructured":"Cabrini L, , Antonelli M, , Savoia G, , Landriscina M. Non-invasive ventilation outside of the intensive care unit: an Italian survey. Minerva Anestesiol, 2011; 77(3):313\u2013322.","journal-title":"Minerva Anestesiol"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2320-7"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-002-1574-1"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201102-0282IM"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181bc8243"}],"container-title":["Respiratory Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.4187\/respcare.03294","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.03294","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.03294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:11:48Z","timestamp":1777615908000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4187\/respcare.03294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,28]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.4187\/respcare.03294"],"URL":"https:\/\/doi.org\/10.4187\/respcare.03294","relation":{},"ISSN":["0020-1324"],"issn-type":[{"value":"0020-1324","type":"print"}],"subject":[],"published":{"date-parts":[[2014,10,28]]}}}